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Method of nucleic acid amplification

  • US 9,902,951 B2
  • Filed: 05/02/2013
  • Issued: 02/27/2018
  • Est. Priority Date: 04/01/1997
  • Status: Expired due to Fees
First Claim
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1. A process that can be used to identify in a nucleic acid sample the presence or absence of nucleic acid sequence differences, wherein each said difference is with respect to one or more reference sequences, the process comprising:

  • a) fragmenting nucleic acids in said sample;

    b) linking adapter sequences to the nucleic acid fragments generated in step a);

    c) binding said nucleic acid fragments to a solid support to form bound nucleic acid fragments, and amplifying said bound nucleic acid fragments; and

    d) identifying nucleic acid sequences within said amplified nucleic acid fragments.

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