Methods and compositions for treatment of a genetic condition
First Claim
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1. A fusion protein comprising a Cas protein and a functional domain in association with a single-guide RNA comprising a sequence selected from the group consisting of SEQ ID NOs:
- 149-158 and 167-215.
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Abstract
Methods and compositions comprising a fusion protein comprising a Cas protein and a functional domain in association with a single guide RNA targeted to an endogenous gene for genetic alteration of cells are provided.
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7 Claims
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1. A fusion protein comprising a Cas protein and a functional domain in association with a single-guide RNA comprising a sequence selected from the group consisting of SEQ ID NOs:
- 149-158 and 167-215.
- View Dependent Claims (2, 3, 4, 5, 6, 7)
Specification