Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte and derived biosensor parameters
First Claim
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1. A method of determining an analyte concentration from a fluid sample with a biosensor having at least two electrodes and a reagent disposed on at least one of the electrodes, the method comprising:
- starting an analyte test sequence upon deposition of a sample on the biosensor;
applying a first signal to the sample to determine a physical characteristic of the sample wherein the physical characteristic is hematocrit level;
driving a second signal to the sample to cause a chemical transformation of the sample;
measuring at least one output signal from the sample;
obtaining a biosensor parametric factor from a look-up table or matrix based on the determined hematocrit level; and
calculating an analyte concentration based on the biosensor parametric factor and the at least one output signal measured at one of a plurality of predetermined time positions from the start of the test sequence based on the relationship;
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Abstract
Various embodiments for a method that allow for a more accurate analyte concentration with a biosensor by determining at least one physical characteristic, typically hematocrit, of the sample containing the analyte and deriving from this characteristic a parameter relating to the biosensor to attain accurate glucose concentration.
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Citations
20 Claims
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1. A method of determining an analyte concentration from a fluid sample with a biosensor having at least two electrodes and a reagent disposed on at least one of the electrodes, the method comprising:
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starting an analyte test sequence upon deposition of a sample on the biosensor; applying a first signal to the sample to determine a physical characteristic of the sample wherein the physical characteristic is hematocrit level; driving a second signal to the sample to cause a chemical transformation of the sample; measuring at least one output signal from the sample; obtaining a biosensor parametric factor from a look-up table or matrix based on the determined hematocrit level; and calculating an analyte concentration based on the biosensor parametric factor and the at least one output signal measured at one of a plurality of predetermined time positions from the start of the test sequence based on the relationship; - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification