Sensor systems and methods of using the same
First Claim
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1. A sensor system, comprising:
- a calibration path configured for fluid communication with a first fluid;
a first valve fluidically coupled to the calibration path;
a sample path isolated from the calibration path, the sample path adapted to be placed in fluid communication with a bodily fluid of a subject and configured to accept at least a portion of the bodily fluid into the sample path,a second valve fluidically coupling the sample path and the calibration path;
a sensor apparatus comprising;
a sensor, wherein the sensor is configured to sense at least one analyte in the bodily fluid, wherein the sensor is coupled with the first valve and reversibly moveable between a first configuration wherein at least a portion of the sensor is located in the calibration path and a second configuration wherein at least a portion of the sensor is extended from the first valve through the second valve into the sample path; and
an actuator and a processing device in operative communication with the actuator, the processing device configured to implement activation of the actuator to move the sensor between its position in the calibration path and its position in the sample path.
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Abstract
Provided are sensor systems and methods for detecting analytes of bodily fluids. The systems can be used to reduce the administration volume of certain compounds and/or fluids during medical monitoring or other procedures by providing a calibration path configured to receive a first fluid, a sample path isolated from the calibration path, the sample path configured to receive a bodily fluid from a subject, and a sensor apparatus comprising at least one sensor selectively positionable between the calibration path and the sample path.
14 Citations
30 Claims
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1. A sensor system, comprising:
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a calibration path configured for fluid communication with a first fluid; a first valve fluidically coupled to the calibration path; a sample path isolated from the calibration path, the sample path adapted to be placed in fluid communication with a bodily fluid of a subject and configured to accept at least a portion of the bodily fluid into the sample path, a second valve fluidically coupling the sample path and the calibration path; a sensor apparatus comprising;
a sensor, wherein the sensor is configured to sense at least one analyte in the bodily fluid, wherein the sensor is coupled with the first valve and reversibly moveable between a first configuration wherein at least a portion of the sensor is located in the calibration path and a second configuration wherein at least a portion of the sensor is extended from the first valve through the second valve into the sample path; andan actuator and a processing device in operative communication with the actuator, the processing device configured to implement activation of the actuator to move the sensor between its position in the calibration path and its position in the sample path. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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25. A method for sensing one or more analytes in a bodily fluid of a subject, comprising:
- positioning an analyte sensor in a first configuration wherein the analyte sensor is positioned in a second valve fluidically coupled to a sample path, the sample path configured in fluid communication with the bodily fluid of the subject, the bodily fluid comprising the one or more analytes;
drawing a volume of the bodily fluid into the sample path such that the analyte sensor contacts the bodily fluid and senses the one or more analytes; positioning the analyte sensor in a second configuration, wherein the analyte sensor is received in a first valve fluidically coupled to a calibration path, the calibration path configured to receive a first fluid; wherein the analyte sensor comprises an actuator, the actuator configured to position at least a portion of the analyte sensor in the calibration path in the first configuration, and to position at least a portion of the analyte sensor in the sample path in the second configuration by reversibly extending the analyte sensor from the first valve and through the second valve; and wherein the second valve fluidically couples the sample path and the calibration path. - View Dependent Claims (26, 27, 28, 29, 30)
- positioning an analyte sensor in a first configuration wherein the analyte sensor is positioned in a second valve fluidically coupled to a sample path, the sample path configured in fluid communication with the bodily fluid of the subject, the bodily fluid comprising the one or more analytes;
Specification