Digital tomosynthesis systems, methods, and computer readable media for intraoral dental tomosynthesis imaging

• US 9,907,520 B2
• Filed: 07/08/2016
• Issued: 03/06/2018
• Est. Priority Date: 06/17/2014
• Status: Active Grant

• Current Assignee: University of North Carolina At Chapel Hill (University of North Carolina System), XinVivo, Inc.
• Original Assignee: University of North Carolina At Chapel Hill (University of North Carolina System), Xintek, Inc.
• Inventors: Zhou, Otto Z., Lu, Jianping, Shan, Jing, Tucker, Andrew, Chtcheprov, Pavel, Platin, Enrique, Mol, Andr, Gaalaas, Laurence Rossman, Wu, Gongting
• Primary Examiner(s): Johnston, Phillip A
• Application Number:
  US15/205,787
• Publication Number:
  US 20160317107A1
• Time in Patent Office: 606 Days
• Field of Search: 378 22
• CPC Class Codes: A61B 6/025 Tomosynthesis
• CPC Class Codes: A61B 6/06 Diaphragms
• CPC Class Codes: A61B 6/4007 characterised by using a plurality of source units
• CPC Class Codes: A61B 6/4035 the source being combined with a filter or grating
• CPC Class Codes: A61B 6/425 using detectors specially adapted to be used in the interior of the body
• CPC Class Codes: A61B 6/4405 the apparatus being movable or portable, e.g. handheld or mounted on a trolley
• CPC Class Codes: A61B 6/461 Displaying means of special interest
• CPC Class Codes: A61B 6/512 Intraoral means
• CPC Class Codes: A61B 6/5205 involving processing of raw data to produce diagnostic data
• CPC Class Codes: A61B 6/5217 extracting a diagnostic or physiological parameter from medical diagnostic data
• CPC Class Codes: A61B 6/547 involving tracking of position of the device or parts of the device
• CPC Class Codes: A61B 6/582 Calibration
• CPC Class Codes: A61B 6/587 Alignment of source unit to detector unit

Abstract

Digital tomosynthesis systems, methods, and computer readable media for intraoral dental tomosynthesis imaging are disclosed. In some aspects, an intraoral tomosynthesis imaging system includes an x-ray source array for positioning outside a mouth of a patient, wherein the x-ray source array contains multiple x-ray focal spots that are spatially distributed on an anode, an area digital x-ray detector for positioning inside the mouth of the patient, a geometry calibration mechanism for connecting the x-ray detector to the x-ray source array, an x-ray collimator for confining x-ray beams to a region of interest, a controller for regulating x-ray radiation and synchronization of the x-ray radiation with the x-ray detector, such that multiple 2D projection images of the ROI are acquired without mechanical motion of the x-ray source array, the x-ray detector, or the mouth of the patient, and a computer program and workstation for 3D tomosynthesis image reconstruction and display.

Claims

1. An intraoral tomosynthesis imaging system comprising:

an x-ray source array for positioning outside a mouth of a patient, wherein the x-ray source array contains multiple x-ray focal spots that are spatially distributed on one or multiple anode(s);

an area digital x-ray detector for positioning inside the mouth of the patient;

an x-ray collimator for confining x-ray beams to a region of interest (ROI);

a controller for regulating x-ray radiation and synchronizing the x-ray exposure with the x-ray detector, such that multiple two-dimensional (2D) projection images of the ROI are acquired without moving the x-ray source array, the area digital x-ray detector, or the mouth of the patient; and

a computer processor for three-dimensional (3D) tomosynthesis image reconstruction and display.

2. The system of claim 1, further comprising a geometry calibration mechanism to determine the relative position of the x-ray detector placed inside the mouth of the patient with respect to the x-ray source array.

3. The system of claim 2, wherein the geometry calibration mechanism comprises a magnetic attachment attachable to the area digital x-ray detector while inside the mouth of the patient in order to connect the x-ray source array to the area digital x-ray detector.

4. The system of claim 1, wherein the x-ray source array is a field emission x-ray source array.

7. The geometry calibration mechanism of claim 2, further configured to provide motion tracking capability during the imaging procedure to dynamically determine the relative position of the x-ray detection with respect to the x-ray source when there is unintentional movement.

8. The geometry calibration device of claim 2, further comprising one or multiple light source(s) mounted on either the x-ray source or the collimator;

a screen;

a camera; and

a mechanism to determine position of the detector with respect to the x-ray source using optical images formed on the screen and captured by the camera.

5. An intraoral three-dimensional (3D) imaging system comprising:

an x-ray source array for positioning outside a mouth of a patient, wherein the x-ray source array contains 3 to 100 x-ray focal spots that are spatially distributed on an anode and spanning an angular range approximately between 3 and 25 degrees, each of the x-ray focal spots being approximately between 0.05 and 2 mm in size;

an area digital x-ray detector for positioning inside the mouth of the patient;

a geometry calibration mechanism connectable to the area digital x-ray detector;

an x-ray collimator for confining x-ray beams to a region of interest (ROI);

an electronic controller for regulating x-ray radiation and synchronization of the x-ray radiation with the area digital x-ray detector, such that multiple two-dimensional (2D) projection images of the ROI are acquired without mechanical motion of the x-ray source array, the area digital x-ray detector, or the mouth of the patient; and

a computer processor with executable programs for geometry calibration, tomosynthesis reconstruction, and image display.

6. A method for dual energy intraoral three-dimensional (3D) tomographic imaging, the method comprising:

positioning an area digital x-ray detector at a first position inside the mouth of the patient;

positioning an x-ray source array outside a mouth of a patient, wherein the x-ray source array comprises multiple x-ray focal spots that are spatially distributed on an anode;

acquiring two sets of two-dimensional (2D) projection images of a same region of interest at two different x-ray energies; and

processing the two sets of 2D projection images to obtain a reconstructed 3D tomography image with high contrast.