Hydrogel implants with porous materials and methods

• US 9,907,663 B2
• Filed: 03/30/2016
• Issued: 03/06/2018
• Est. Priority Date: 03/31/2015
• Status: Active Grant

• Current Assignee: Cartiva, Inc. (Stryker Corporation)
• Original Assignee: Cartiva, Inc. (Stryker Corporation)
• Inventors: Patrick, Timothy J., Ramey, Carribeth B., Tudor, Letitia, Axelrod, Michael A.
• Primary Examiner(s): Prone, Christopher D
• Assistant Examiner(s): Ganesan, Suba
• Application Number:
  US15/085,840
• Publication Number:
  US 20160287392A1
• Time in Patent Office: 706 Days
• CPC Class Codes: A61B 17/86 Pins or screws or threaded wires; nuts therefor A61B17/72 take precedence
• CPC Class Codes: A61F 2/30756 Cartilage endoprostheses A61F2/3603 takes precedence
• CPC Class Codes: A61F 2/3094 Designing or manufacturing processes
• CPC Class Codes: A61F 2/30942 for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
• CPC Class Codes: A61F 2/3872 Meniscus for implantation between the natural bone surfaces
• CPC Class Codes: A61F 2/4618 of cartilage
• CPC Class Codes: A61F 2002/30011 differing in porosity
• CPC Class Codes: A61F 2002/30075 swellable, e.g. when wetted
• CPC Class Codes: A61F 2002/3021 frustoconical
• CPC Class Codes: A61F 2002/30224 cylindrical
• CPC Class Codes: A61F 2002/30273 pyramidal
• CPC Class Codes: A61F 2002/30299 umbrella-shaped or mushroom-shaped
• CPC Class Codes: A61F 2002/30327 differing in diameter
• CPC Class Codes: A61F 2002/30331 made by longitudinally pushing a protrusion into a complementarily-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2002/30462 retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2002/305 Snap connection
• CPC Class Codes: A61F 2002/30579 with mechanically expandable devices, e.g. fixation devices
• CPC Class Codes: A61F 2002/30761 Support means for artificial cartilage, e.g. cartilage defect covering membranes
• CPC Class Codes: A61F 2002/30841 Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
• CPC Class Codes: A61F 2002/3085 with a threaded, e.g. self-tapping, bone-engaging surface, e.g. external surface
• CPC Class Codes: A61F 2002/3092 : having an open-celled or open-pored structure
• CPC Class Codes: A61F 2002/30957 : using a positive or a negative model, e.g. moulds
• CPC Class Codes: A61F 2310/00017 : Iron- or Fe-based alloys, e.g. stainless steel
• CPC Class Codes: A61F 2310/00023 : Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00047 : Aluminium or Al-based alloys
• CPC Class Codes: A61F 2310/00089 : Zirconium or Zr-based alloys
• CPC Class Codes: A61F 2310/00185 : based on metal oxides

Abstract

An implant system includes a first portion, a second portion, and a third portion. The first portion includes a hydrogel. The second portion includes a porous material and the hydrogel in pores of the porous material. The third portion includes the porous material. The first portion is free of the porous material. The third portion is free of the hydrogel. Methods of making and using the implant system.

Claims

1. An implant system configured for implantation in a joint, the implant system comprising:

a first part comprising an implant comprising;

a first portion comprising a hydrogel;

a second portion comprising a porous material and the hydrogel in pores of the porous material; and

a third portion comprising the porous material,

the first portion being free of the porous material, and

the third portion being free of the hydrogel; and

a second part comprising;

sidewalls;

a bottom;

a cavity at least partially defined by the sidewalls and the bottom, the cavity configured to at least partially receive the implant; and

an anchoring element, wherein the anchoring element comprises an anchor comprising;

an insert;

a finger extending radially outwardly and towards a top of the implant system;

a wire threaded through holes in the bottom of the second part; and

a knot configured to be tightened upon pulling of ends of the wire.

2. The implant system of claim 1, wherein the porous material comprises a toroidal shape.

3. The implant system of claim 1, wherein the porous material comprises a detent extending radially inward.

4. The implant system of claim 1, wherein one of the porous material and the sidewalls of the second part comprises a detent and the other of the porous material and the sidewalls of the second part comprises a groove configured to interact with the detent when the implant is at least partially in the cavity of the second part.

5. The implant system of claim 1, wherein the ends of the wire form a loop.

6. The implant system of claim 1, wherein the first portion comprises a contoured surface, and wherein the contoured surface is customized for a particular subject based on scan data.

7. The implant system of claim 6, wherein the scan data comprises at least one of computerized tomography, computerized axial tomography, positron emission tomography, and magnetic resonance imaging.

8. The implant system of claim 1, wherein the porous material comprises at least one of aluminum, alumina, zirconia, titanium, titania, stainless steel, PEEK, and steatite.

9. The implant system of claim 1, wherein the porous material has a porosity between 45 ppi and 80 ppi.

10. The implant system of claim 1, wherein pores of the porous material have a dimension between 100 μ

m and 500 μ

m.

11. The implant system of claim 1, wherein the first portion comprises a hemispherical shape or a wedge shape.

12. An implant system configured for implantation in a joint, the implant system comprising:

a first part comprising an implant comprising;

a first portion comprising a hydrogel;

a second portion comprising a porous material and the hydrogel in pores of the porous material; and

a third portion comprising the porous material,

the first portion being free of the porous material, and

the third portion being free of the hydrogel; and

a second part comprising;

sidewalls;

a bottom;

a cavity at least partially defined by the sidewalls and the bottom, the cavity configured to at least partially receive the implant; and

an anchoring element, wherein the anchoring element comprises;

a hole in the bottom of the second part;

a screw configured to extend through the hole in the bottom of the second part;

a hole in the sidewalls of the second part; and

a second screw configured to extend through the hole in the sidewalls of the second part.

13. The implant system of claim 12, wherein one of the porous material and the sidewalls of the second part comprises a detent and the other of the porous material and the sidewalls of the second part comprises a groove configured to interact with the detent when the implant is at least partially in the cavity of the second part.

14. The implant system of claim 12, wherein the porous material comprises a toroidal shape.

15. The implant system of claim 12, wherein the porous material comprises a detent extending radially inward.

16. The implant system of claim 12, wherein the first portion comprises a contoured surface, and wherein the contoured surface is customized for a particular subject based on scan data.

17. The implant system of claim 16, wherein the scan data comprises at least one of computerized tomography, computerized axial tomography, positron emission tomography, and magnetic resonance imaging.

18. The implant system of claim 12, wherein the porous material comprises at least one of aluminum, alumina, zirconia, titanium, titania, stainless steel, PEEK, and steatite.

19. The implant system of claim 12, wherein the porous material has a porosity between 45 ppi and 80 ppi.

20. The implant system of claim 12, wherein pores of the porous material have a dimension between 100 μ

m and 500 μ

m.

21. The implant system of claim 12, wherein the first portion comprises a hemispherical shape or a wedge shape.