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Two-layer separation-type eye drop containing squalane

  • US 9,907,750 B2
  • Filed: 03/18/2014
  • Issued: 03/06/2018
  • Est. Priority Date: 03/19/2013
  • Status: Active Grant
First Claim
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1. A two-layer separation-type ophthalmic solution comprising an oil-containing layer and an aqueous layer, whereinwhen statically stored, an upper layer consisting of the oil-containing layer and a lower layer consisting of the aqueous layer are formed, the oil-containing layer contains squalane,the aqueous layer contains hyaluronic acid and/or its salt and polyvinyl alcohol, with 0.3 to 0.4 w/v % of hyaluronic acid and/or its salt and 0.025 to 0.1 w/v % of polyvinyl alcohol being present in the ophthalmic solution.

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