Catheter pump with positioning brace

• US 9,907,890 B2
• Filed: 04/15/2016
• Issued: 03/06/2018
• Est. Priority Date: 04/16/2015
• Status: Active Grant

• Current Assignee: TC1 LLC (Abbott Laboratories Incorporated)
• Original Assignee: TC1 LLC (Abbott Laboratories Incorporated)
• Inventors: Muller, Paul F.
• Primary Examiner(s): MAHMOOD, NADIA AHMAD
• Application Number:
  US15/130,170
• Publication Number:
  US 20160303299A1
• Time in Patent Office: 690 Days
• Field of Search: 600 16
• CPC Class Codes: A61M 60/13 by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/174 discharging the blood to the ventricle or arterial system via a cannula internal to the ventricle or arterial system
• CPC Class Codes: A61M 60/237 the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
• CPC Class Codes: A61M 60/414 transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
• CPC Class Codes: A61M 60/422 the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
• CPC Class Codes: A61M 60/806 Vanes or blades
• CPC Class Codes: A61M 60/824 Hydrodynamic or fluid film bearings
• CPC Class Codes: A61M 60/829 having a purge fluid supply
• CPC Class Codes: A61M 60/857 Implantable blood tubes
• CPC Class Codes: A61M 60/861 Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient's body

Abstract

A catheter pump assembly is provided that includes an elongate body assembly, a shaft, and an impeller. The assembly has a proximal end, a distal end and at least one lumen extending therebetween. The shaft is disposed at least partially within the elongate body, e.g., in the at least one lumen, and journaled for rotation. The impeller is coupled with a distal portion of the shaft. The impeller is configured to be rotated to induce flow of blood when the impeller is placed in fluid communication with a source of blood. An inflatable balloon brace is disposed on an outer surface of the catheter pump. The inflatable balloon brace is spaced proximally of the impeller and has a low profile configuration for delivery through the vasculature and an expanded configuration for disposing (e.g., position and/or orienting) the impeller within the source of blood.

Claims

1. A catheter pump assembly, comprising:

an elongate body assembly having a proximal end, a distal end and at least one lumen extending therebetween;

a shaft disposed at least partially within the elongate body and journaled for rotation;

an impeller coupled with a distal portion of the shaft, the impeller configured to be rotated to induce flow of blood when the impeller is placed in fluid communication with a source of blood; and

an anchor disposed along an outer surface of the catheter pump assembly at an intermediate location and configured to be deployed therefrom to engage a vascular segment to hold in place a portion of the catheter pump assembly disposed in the patient.

2. The catheter pump assembly of claim 1, wherein the anchor comprises an inflatable balloon brace disposed on an outer surface of the catheter pump assembly, the inflatable balloon brace being spaced proximally from the impeller and having a low profile configuration for delivery through the vasculature and an expanded configuration for disposing the impeller within the source of blood.

3. The catheter pump assembly of claim 2, wherein the inflatable balloon brace comprises the at least one flow-through channel disposed therein.

4. The catheter pump assembly of claim 3, wherein the at least one channel is bounded by the inflatable balloon brace or by the elongate body.

5. The catheter pump assembly of claim 2, wherein the elongate body assembly comprises a catheter body and a sheath disposed over the catheter body, the inflatable balloon brace being disposed on the catheter body.

6. The catheter pump assembly of claim 5, wherein the sheath comprises a cylindrical distal portion surrounding the catheter body, the sheath comprising a first position in which the cylindrical distal portion is disposed over the inflatable balloon brace and a second position which the inflatable balloon brace is exposed.

7. The catheter pump assembly of claim 1, wherein the elongate body assembly has a length sufficient to extend from a peripheral vascular location to a ventricle of the heart.

8. The catheter pump assembly of claim 2, wherein the inflatable brace is positioned on the elongate body assembly such that when the elongate body assembly extends between the left ventricle and a peripheral arterial location, the inflatable brace is disposed in the descending aorta.

9. The catheter pump assembly of claim 2, wherein the inflatable brace is configured to bias a portion of the elongate body assembly against a superior aspect of the aortic arch when the elongate body assembly extends between the left ventricle and a peripheral vascular location.

10. The catheter pump assembly of claim 2, wherein the inflatable brace comprises a torus portion, wherein the elongate body assembly is disposed between the torus and the axis of revolution of the torus portion.

11. The catheter pump assembly of claim 10, wherein the torus portion is disposed about a portion of the elongate body assembly and further comprises an inflation channel extending between an inflation lumen in the elongate body assembly and an interior space of the torus.

12. The catheter pump assembly of claim 11, further comprising one or more blood flow channels defined at least in part by a surface of the torus.

13. The catheter pump assembly of claim 1, wherein the anchor comprises a plurality of lobes having a compressed configuration and an expanded configuration, the lobes extending outwardly from the elongate body assembly in the expanded configuration such that distal ends of the lobes contact the vascular segment during operation of the catheter pump assembly.

14. A method of positioning a catheter pump, comprising:

inserting a catheter pump into a peripheral vascular location, the catheter pump having an elongate body, a flow generating device disposed at a distal portion of the elongate body, and an anchor disposed proximally of the flow generating device;

advancing the distal portion of the elongate body to a source of blood;

expanding the brace from a side surface of the elongate body into contact with a target location within the patient; and

operating the flow generating device within the source of blood to induce a blood flow.

15. The method of claim 14, wherein the brace comprises an inflation chamber in fluid communication with an inflation lumen disposed in the elongate body and wherein expanding the brace comprises flowing an inflation medium into the inflation chamber.

16. The method of claim 14, wherein advancing comprises positioning the flow generating device in fluid communication with a left ventricle.

17. The method of claim 16, wherein advancing comprises positioning the flow generating device at least partially within the left ventricle.

18. The method of claim 14, wherein the target location includes the descending aorta between the left subclavian artery and the peripheral vascular location.

19. The method of claim 14, wherein the target location includes the ascending aorta between the heart and the brachiocephalic artery.

20. The method of claim 14, wherein the target location includes the ascending aorta between the coronary arteries and brachiocephalic artery.

21. The method of claim 14, wherein the brace is configured to position the distal portion asymmetrically in the vasculature when inflated, and further comprising orienting the elongate body such that the distal portion of the elongate body extends between a central region of and an outer wall of the ascending aorta.