Precise accurate measurement of the administration of drugs using the injection method by means of ultrasonic pulse-echo principles

• US 9,907,902 B2
• Filed: 12/02/2014
• Issued: 03/06/2018
• Est. Priority Date: 12/20/2013
• Status: Active Grant

• Current Assignee: Maxim Integrated Products, Inc. (Analog Devices, Inc.)
• Original Assignee: Maxim Integrated Products, Inc. (Analog Devices, Inc.)
• Inventors: Mitrosky, Jim, Amadio, Roberto, Lander, Mike
• Primary Examiner(s): SCHMIDT, EMILY LOUISE
• Application Number:
  US14/557,796
• Publication Number:
  US 20150174342A1
• Time in Patent Office: 1,190 Days
• CPC Class Codes: A61M 2205/0294 Piezoelectric materials
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3375 Acoustical, e.g. ultrasonic, measuring means
• CPC Class Codes: A61M 2205/3379 Masses, volumes, levels of fluids in reservoirs, flow rates
• CPC Class Codes: A61M 2205/3382 Upper level detectors
• CPC Class Codes: A61M 2205/3389 Continuous level detection A61M2205/3393 takes precedence
• CPC Class Codes: A61M 2205/3553 remote, e.g. between patient's home and doctor's office
• CPC Class Codes: A61M 2205/43 making noise when used correctly
• CPC Class Codes: A61M 2205/505 Touch-screens; Virtual keyboard or keypads; Virtual buttons; Soft keys; Mouse touches
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/583 by visual feedback
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 2209/01 Remote controllers for specific apparatus
• CPC Class Codes: A61M 5/1411 Drip chambers A61M5/162, A61M5/1689, A61M5/40 take precedence
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/31525 Dosing burettes, pipettes B01L3/02
• CPC Class Codes: A61M 5/365 Air detectors A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626
• CPC Class Codes: G01F 11/027 of the syringe type

Abstract

A dosage control system includes a syringe and a dosage control module. The syringe includes a barrel and a plunger. The plunger includes a plunger seal located within the barrel and the barrel includes an end configured to connect to a needle. The dosage control module measures a first distance between the plunger seal and the end of the barrel, measures at least one second distance between the plunger seal and the end of the barrel, determines whether a predetermined amount of medication has been administered from the syringe based on a difference between the first distance and the at least one second distance, and selectively activates at least one of a visual indication and an audio indication if the predetermined amount of medication has been administered from the syringe.

Claims

1. A dosage control system comprising:

a syringe including a barrel and a plunger, wherein the plunger includes a plunger seal located within the barrel, and wherein the barrel includes an end configured to connect to a needle, wherein

the plunger seal includes a reflective surface, wherein the reflective surface (i) is located within the barrel opposite the end configured to connect to the needle and (ii) faces the end of the barrel configured to connect to the needle, and

the end of the barrel configured to connect to the needle includes a piezoelectric transducer arranged to transmit a plurality of sound pulses from the end of the barrel configured to connect to the needle, through medication contained within the barrel, and toward the plunger seal, wherein the piezoelectric transducer is attached to an inner surface of the end of the barrel; and

a dosage control module that determines the type of the medication contained within the barrel of the syringe and, based on (i) the determined type of the medication contained within the barrel of the syringe and (ii) the sound pulses transmitted through the medication, measures a first distance between the plunger seal and the end of the barrel configured to connect to the needle, measures at least one second distance between the plunger seal and the end of the barrel configured to connect to the needle, determines whether a predetermined amount of medication has been administered from the syringe based on a difference between the first distance and the at least one second distance, and selectively activates at least one of a visual indication and an audio indication if the predetermined amount of medication has been administered from the syringe.

2. The dosage control system of claim 1, wherein the dosage control module measures the first distance and the at least one second distance based on an amount of time for the plurality of sound pulses to travel between the end of the barrel configured to connect to the needle and the plunger seal.

3. The dosage control system of claim 2, wherein the dosage control module transmits a plurality of voltage pulses to the piezoelectric transducer, the piezoelectric transducer converts the plurality of voltage pulses into the plurality of sound pulses, and the plurality of sound pulses are reflected back to the piezoelectric transducer from the reflective surface.

4. The dosage control system of claim 2, wherein the dosage control module includes a time-to-digital converter that calculates the amount of time.

5. The dosage control system of claim 1, wherein the dosage control module determines the type of the medication contained within the barrel of the syringe using information input via a user interface.

6. The dosage control system of claim 1, wherein the dosage control module:

transmits a series of calibration pulses with the plunger in a known position to determine a duration for the calibration pulses to travel through the medication; and

measures the first distance between the plunger seal and the end of the barrel configured to connect to the needle and measures the at least one second distance between the plunger seal and the end of the barrel configured to connect to the needle based on the determined duration for the calibration pulses to travel through the medication with the plunger in the known position.

7. The dosage control system of claim 6, wherein the known position is a fully withdrawn position of the plunger.

8. The dosage control system of claim 1, wherein (i) the first distance corresponds to an amount the plunger is withdrawn to draw the medication into the barrel and (ii) the second distance corresponds to an amount the plunger is pressed to administer the medication from the barrel.

9. The dosage control system of claim 1, further comprising an air bubble detection module that determines whether air bubbles are present within the medication based on the sound pulses transmitted through the medication.