Devices and systems for accessing cardiac tissue
First Claim
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1. A system for engaging heart tissue, comprising:
- an engagement catheter, comprising;
an elongated tube comprising a proximal end, a distal end, and a single internal lumen extending between the proximal end and the distal end;
a vacuum port in communication with the proximal end of the tube, the vacuum port operatively connected to the single internal lumen and capable of operative connection to a vacuum source; and
a suction port in communication with the single internal lumen at or near the distal end of the tube, the suction port configured to removably engage a targeted tissue on the interior of a wall of a heart, such that the suction port is capable of forming a reversible seal with the wall of the heart when the vacuum source is operatively attached to the vacuum port;
wherein the engagement catheter is configured for percutaneous intravascular insertion into a patient through a blood vessel of the patient and further configured for advancement to the targeted tissue through the blood vessel;
wherein the suction port is configured to removably attach to the targeted tissue under vacuum applied from the vacuum source after introduction of a portion of the engagement catheter into the blood vessel;
wherein the engagement catheter is configured to permit at least a portion of the engagement catheter to be retracted after percutaneous intravascular insertion, while remaining removably attached to the targeted tissue due to vacuum from the vacuum source through the single internal lumen of the engagement catheter and suction engagement from the suction port, so to locally increase a distance between the targeted tissue and a pericardium surrounding the heart; and
a second device, the second device selected from the group consisting of a delivery catheter and a needle; and
wherein the engagement catheter is configured to receive the second device delivered through the vacuum port into the single internal lumen of the engagement catheter and to permit operation of the second device within the single internal lumen while maintaining the reversible seal under vacuum.
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Abstract
Devices, systems, and methods for accessing the internal and external tissues of the heart are disclosed. At least some of the embodiments disclosed herein provide access to the external surface of the heart through the pericardial space for localized delivery of substances to the heart tissue. In addition, various disclosed embodiments provide access to the internal surface of the heart for aspiration and delivery of substances to a targeted region without disturbing or interfering with nearby structures or surfaces.
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Citations
18 Claims
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1. A system for engaging heart tissue, comprising:
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an engagement catheter, comprising; an elongated tube comprising a proximal end, a distal end, and a single internal lumen extending between the proximal end and the distal end; a vacuum port in communication with the proximal end of the tube, the vacuum port operatively connected to the single internal lumen and capable of operative connection to a vacuum source; and a suction port in communication with the single internal lumen at or near the distal end of the tube, the suction port configured to removably engage a targeted tissue on the interior of a wall of a heart, such that the suction port is capable of forming a reversible seal with the wall of the heart when the vacuum source is operatively attached to the vacuum port; wherein the engagement catheter is configured for percutaneous intravascular insertion into a patient through a blood vessel of the patient and further configured for advancement to the targeted tissue through the blood vessel; wherein the suction port is configured to removably attach to the targeted tissue under vacuum applied from the vacuum source after introduction of a portion of the engagement catheter into the blood vessel; wherein the engagement catheter is configured to permit at least a portion of the engagement catheter to be retracted after percutaneous intravascular insertion, while remaining removably attached to the targeted tissue due to vacuum from the vacuum source through the single internal lumen of the engagement catheter and suction engagement from the suction port, so to locally increase a distance between the targeted tissue and a pericardium surrounding the heart; and a second device, the second device selected from the group consisting of a delivery catheter and a needle; and wherein the engagement catheter is configured to receive the second device delivered through the vacuum port into the single internal lumen of the engagement catheter and to permit operation of the second device within the single internal lumen while maintaining the reversible seal under vacuum. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A system for use with a vacuum source for engaging a tissue, the system comprising:
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an engagement catheter comprising; a single lumen extending between a proximal end and a distal end; a suction port located at or near the distal end of the engagement catheter and in communication with the single lumen of the engagement catheter, the suction port configured to allow the distal end to removably engage a surface of a bodily tissue; and a vacuum port located at the proximal end of the engagement catheter, the vacuum port in communication with the single lumen of the engagement catheter and capable of operative connection to a vacuum source; wherein the engagement catheter is configured for percutaneous intravascular insertion into a patient through a blood vessel and advancement to the surface of the bodily tissue; wherein when a vacuum source is operatively attached to the vacuum port, the distal end is capable of forming a reversible seal with the surface of the bodily tissue;
wherein the engagement catheter is configured to locally increase a distance between the bodily tissue and a second tissue behind the first tissue by retracting the bodily tissue away from the second tissue while the reversible seal is formed; anda second device, the second device selected from the group consisting of a delivery catheter and a needle; and wherein the engagement catheter is configured to receive the second device delivered through the vacuum port into the single lumen of the engagement catheter and to permit operation of the second device within the single lumen while maintaining the reversible seal under vacuum. - View Dependent Claims (8, 9, 10, 11)
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12. A system for engaging mammalian tissue, comprising:
an engagement catheter, comprising; an elongated tube comprising a proximal end, a distal end, and a single internal lumen extending between the proximal end and the distal end; a vacuum port in communication with the proximal end of the tube, the vacuum port operatively connected to the single internal lumen and capable of operative connection to a vacuum source; and a suction port in communication with the single internal lumen at or near the distal end of the tube, the suction port configured to removably engage a targeted tissue, such that the suction port is capable of forming a reversible seal with the targeted tissue when the vacuum source is operatively attached to the vacuum port; wherein the engagement catheter is configured for percutaneous intravascular insertion into a patient through a blood vessel and advancement to the targeted tissue; wherein the suction port is configured to removably attach to the targeted tissue under vacuum applied from the vacuum source after introduction of a portion of the engagement catheter into the blood vessel;
wherein the engagement catheter is configured to permit at least a portion of the engagement catheter to be retracted after percutaneous intravascular insertion, while remaining removably attached to the targeted tissue due to vacuum from the vacuum source through the single internal lumen of the engagement catheter and suction engagement from the suction port, so to locally increase a distance between the targeted tissue and a second tissue behind the bodily tissue; anda second device, the second device selected from the group consisting of a delivery catheter and a needle; and wherein the engagement catheter is configured to receive the second device delivered through the vacuum port into the single internal lumen of the engagement catheter and permit operation of the second device within the single internal lumen while maintaining the reversible seal under vacuum. - View Dependent Claims (13, 14, 15, 16, 17, 18)
Specification