Apparatus and method for spinal cord stimulation to treat pain

• US 9,907,960 B2
• Filed: 07/22/2016
• Issued: 03/06/2018
• Est. Priority Date: 06/14/2013
• Status: Active Grant

• Current Assignee: Biotronik SE & Company KG
• Original Assignee: Biotronik SE & Company KG
• Inventors: Lian, Jie, Muessig, Dirk
• Primary Examiner(s): Bertram, Eric D.
• Application Number:
  US15/217,258
• Publication Number:
  US 20160325100A1
• Time in Patent Office: 592 Days
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36139 with automatic adjustment
• CPC Class Codes: A61N 1/3614 based on impedance measurement

Abstract

A spinal cord stimulation device having a stimulation unit for generation and delivery of stimulation pulses, a control unit for controlling the stimulation unit with respect to stimulation intensity and an autonomic nervous system (“ANS”) sensing unit that is configured to generate ANS indicating signals that represent an increased sympathetic tone or an increased parasympathetic tone, respectively. The control unit is configured to control the intensity of respective stimulation pulses depending on a respective ANS indicating signal as generated by said ANS sensing unit.

Claims

1. A method for controlling a spinal cord stimulation device, said method comprising the steps of:

acquiring values of a parameter that is indicative for a status of an autonomic nervous system;

evaluating acquired values of said parameter that is indicative for a status of an autonomic nervous system;

generating a control signal based on the evaluation; and

controlling generation of stimulation pulses depending on said control signal,

wherein the parameter that is indicative for a status of an autonomic nervous system is respiration activity,

wherein evaluating acquired values representing respiration activity includes determining respiration phases, and

wherein evaluating acquired values representing respiration activity includes determining respiration phases.

2. The method according to claim 1, wherein the respiration phases include inspiration, expiration, post-inspiration pause, and post-expiration pause.

3. The method according to claim 1, further comprising sensing values of an electric parameter which depends on a respective respiration phase.

4. The method according to claim 3, wherein the electric parameter comprises transthoracic impedance, and wherein the method further comprises generating transthoracic impedance signals that represent values of sensed transthoracic impedance.

5. The method according to claim 4, wherein the electric parameter comprises transthoracic impedance, and wherein the method further comprises generating transthoracic impedance signals that represent values of sensed transthoracic impedance.