Device configured for real-time pressure sensing

• US 9,913,959 B2
• Filed: 04/15/2015
• Issued: 03/13/2018
• Est. Priority Date: 10/07/2009
• Status: Active Grant

• Current Assignee: Endophys Holdings, LLC
• Original Assignee: Endophys Holdings, LLC
• Inventors: Purdy, Phillip D., Ferry, Steven J.
• Primary Examiner(s): Gilbert, Andrew
• Assistant Examiner(s): Shah, Nilay
• Application Number:
  US14/687,761
• Publication Number:
  US 20150289816A1
• Time in Patent Office: 1,063 Days
• Field of Search: 604 65
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2090/064 for measuring force, pressure or mechanical tension
• CPC Class Codes: A61B 2562/12 Manufacturing methods specially adapted for producing sensors for in-vivo measurements
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/02154 by optical transmission
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/0261 using optical means, e.g. infrared light
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61M 2025/0001 for pressure measurement
• CPC Class Codes: A61M 2025/0002 with a pressure sensor at the distal end
• CPC Class Codes: A61M 2025/0003 having an additional lumen transmitting fluid pressure to the outside for measurement
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 25/0012 with embedded structures, e.g. coils, braids, meshes, strands or radiopaque coils
• CPC Class Codes: A61M 25/005 with embedded materials for reinforcement, e.g. wires, coils, braids
• CPC Class Codes: A61M 25/0097 characterised by the hub connectors A61M39/10
• CPC Class Codes: Y10T 29/49002 Electrical device making

Abstract

Medical devices, perfusion systems, and methods for detecting a pressure within a space in a subject and for perfusion of fluid into a space in a subject. The space may be a fluid-filled space, or a space that is depleted of fluid due to an obstruction to fluid flow into the space. Methods for forming the medical devices.

Claims

1. A medical device comprising:

an elongated body having a wall that defines a first lumen and a sensor lumen positioned in the wall;

a stiffener embedded in the wall, the stiffener surrounding the first lumen and positioned between the first lumen and the sensor lumen;

a sensor positioned in the sensor lumen;

wherein the sensor lumen is separate from the first lumen and not in fluid communication with the first lumen, and wherein the sensor lumen does not impinge on the first lumen, the elongated body comprising a first end and a second end;

wherein the first lumen extends from the first end to the second end such that both the first and second ends are open; and

wherein the sensor lumen comprises an opening along a distal end of the elongated body to provide access to an anatomical space within a subject in which the elongated body is positioned; and

a hub secured to a proximal end of the elongated body, the hub comprising a hub primary lumen, a hub sensor lumen and a flushing lumen in fluid communication with the hub primary lumen, the hub primary lumen being in fluid communication with the first lumen of the elongated body, and the hub sensor lumen being in fluid communication with the sensor lumen of the elongated body;

wherein the hub primary lumen is separate from the hub sensor lumen, such that the hub primary lumen is not in direct fluid communication with the hub sensor lumen.

2. The device of claim 1, wherein the stiffener comprises at least one of a metal, a metal alloy and a polymeric material.

3. The device of claim 2, wherein the stiffener comprises at least one of stainless steel, nitinol, tantalum, platinum, cobalt, titanium, gold, iridium, silver, tungsten and another biocompatible metal or metal alloy.

4. The device of claim 1, wherein the sensor is connected to a transmission line, a portion of the transmission line being positioned in the sensor lumen.

5. The device of claim 1, further comprising:

an embedding medium that secures the sensor to the elongated body.

6. The device of claim 1, wherein the sensor is positioned such that it can detect a parameter through the opening along the distal end of the elongated body.

7. The device of claim 1, wherein the opening is proximal to the distal end, and the sensor is positioned such that it can detect a parameter through the opening.

8. The device of claim 1, wherein the sensor comprises a fiber optic sensor.

9. The medical device of claim 4, wherein the sensor comprises a fiber optic sensor and the transmission line comprises an optic fiber.

10. The device of claim 1, wherein the sensor lumen is bounded, at least in part, by a liner.

11. The device of claim 10, wherein the liner comprises a metal.

12. A medical device comprising:

an elongated body having a wall that defines a first lumen and a second lumen positioned in the wall;

a stiffener embedded in the wall, the stiffener surrounding the first lumen and positioned between the first lumen and the second lumen; and

a sensor positioned at least partially in the second lumen;

wherein the second lumen is separate from the first lumen and not in fluid communication with the first lumen; and

wherein the second lumen terminates at an opening along a distal end of the second lumen to provide access to an anatomical space within a subject in which the elongated body is positioned; and

a hub positioned along a proximal end of the elongated body, the hub comprising a hub primary lumen, a hub sensor lumen and a flushing lumen in fluid communication with the hub primary lumen, the hub primary lumen being in fluid communication with the first lumen of the elongated body, and the hub sensor lumen being in fluid communication with the second lumen of the elongated body;

wherein the hub primary lumen is separate from the hub sensor lumen, such that the hub primary lumen is not in direct fluid communication with the hub sensor lumen.

13. The device of claim 12, wherein the sensor is connected to a transmission line, a portion of the transmission line being positioned in the second lumen.

14. The device of claim 12, further comprising:

an embedding medium that secures the sensor to the elongated body.

15. The device of claim 12, wherein the sensor is positioned such that it can detect a parameter through the opening.

16. The device of claim 12, wherein the opening is proximal to the distal end, and the sensor is positioned such that it can detect a parameter through the opening.

17. The device of claim 12, wherein the sensor comprises a fiber optic sensor.

18. The medical device of claim 12, wherein the sensor comprises a fiber optic sensor and the transmission line comprises an optical fiber.

19. The device of claim 12, wherein the second lumen is bounded, at least in part, by a liner.