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Systems and methods for stimulating and monitoring biological tissue

  • US 9,913,976 B2
  • Filed: 06/16/2011
  • Issued: 03/13/2018
  • Est. Priority Date: 06/19/2006
  • Status: Active Grant
First Claim
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1. A system for stimulating and monitoring tissue, the system comprising:

  • a first non-invasive energy source that emits an electric field;

    a second non-invasive energy source that emits a mechanical field;

    an imaging device; and

    a controller comprising one or more programs that are configured to tune stimulation by identifying tissue distribution data of a subject from imaging data received from the imaging device, determining tissue boundaries in a stimulation area from the tissue distribution data, constructing a computational mesh that captures tissue segmentation demonstrated in the imaging data and accounts for tissue distribution and tissue boundaries, and calculating altered tissue mechanical properties in the stimulation area relative to the electrical field to be applied in the stimulation area, wherein the controller outputs a dose to be provided by the first and/or second non-invasive energy sources.

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