Obstructive sleep apnea treatment devices, systems and methods
First Claim
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1. A method of delivering a nerve stimulation therapy to a subject via an implanted neurostimulator connected to a stimulation delivery lead, the method comprising:
- delivering the nerve stimulation therapy at a first intensity during a first therapy period of the nerve stimulation therapy, wherein the first intensity is within a range having a lower bound and an upper bound, wherein the subject is awake during at least an initial portion of the first therapy period, and wherein the upper bound is a discomfort threshold; and
delivering the nerve stimulation therapy at a second intensity during a second therapy period of the nerve stimulation therapy subsequent to the first therapy period, wherein the second intensity is different from the first intensity, wherein the subject is asleep during at least an initial portion of the second therapy period,wherein the nerve stimulation therapy is delivered to a nerve for treating a respiratory condition of the subject.
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Abstract
Devices, systems and methods of neurostimulation for treating obstructive sleep apnea. The system is adapted to send an electrical signal from an implanted neurostimulator through a stimulation lead to a patient'"'"'s nerve at an appropriate phase of the respiratory cycle based on input from a respiration sensing lead. External components are adapted for wireless communication with the neurostimulator. The neurostimulator is adapted to deliver therapeutic stimulation based on inputs.
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Citations
31 Claims
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1. A method of delivering a nerve stimulation therapy to a subject via an implanted neurostimulator connected to a stimulation delivery lead, the method comprising:
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delivering the nerve stimulation therapy at a first intensity during a first therapy period of the nerve stimulation therapy, wherein the first intensity is within a range having a lower bound and an upper bound, wherein the subject is awake during at least an initial portion of the first therapy period, and wherein the upper bound is a discomfort threshold; and delivering the nerve stimulation therapy at a second intensity during a second therapy period of the nerve stimulation therapy subsequent to the first therapy period, wherein the second intensity is different from the first intensity, wherein the subject is asleep during at least an initial portion of the second therapy period, wherein the nerve stimulation therapy is delivered to a nerve for treating a respiratory condition of the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A method of delivering a nerve stimulation therapy to a subject via an implanted neurostimulator connected to a stimulation delivery lead, the method comprising:
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delivering the nerve stimulation therapy at a first intensity during a first therapy period of the therapy, wherein the first intensity is within a range having a lower bound and an upper bound wherein the subject is awake during at least an initial portion of the first therapy period, and wherein the upper bound is a discomfort threshold; transitioning from the first therapy period to a second therapy period of the nerve stimulation therapy subsequent to the first therapy period, the transitioning comprising a cessation of stimulation; and delivering the nerve stimulation therapy at a second intensity during the second therapy period, wherein the second intensity is greater than the first intensity and the discomfort threshold wherein the subject is asleep during at least an initial portion of the second therapy period, wherein the nerve stimulation therapy is delivered to a nerve for treating a respiratory condition of the subject. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30)
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31. A method of delivering a nerve stimulation therapy to a subject via an implanted neurostimulator connected to a stimulation delivery lead, the method comprising:
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delivering the nerve stimulation therapy at a first intensity during a first therapy period of the nerve stimulation therapy, wherein the first intensity is within a range having a lower bound and an upper bound, wherein the subject is awake during at least an initial portion of the first therapy period, and wherein the upper bound is a threshold determined based on feedback from the subject; and delivering the nerve stimulation therapy at a second intensity during a second therapy period of the nerve stimulation therapy subsequent to the first therapy period, wherein the second intensity is different from the first intensity, and wherein the subject is asleep during at least an initial portion of the second therapy period, wherein the nerve stimulation therapy is delivered to a nerve for treating a respiratory condition of the subject.
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Specification