Methods of using high intensity focused ultrasound to form an ablated tissue area containing a plurality of lesions

• US 9,931,134 B2
• Filed: 07/05/2017
• Issued: 04/03/2018
• Est. Priority Date: 05/25/2006
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Hissong, James B., Stewart, Mark T., Francischelli, David E., Keogh, James R., Lee, Hotaik, Smith, Nadine B., Skarda, James R.
• Primary Examiner(s): Brutus, Joel F
• Application Number:
  US15/641,369
• Publication Number:
  US 20170296217A1
• Time in Patent Office: 272 Days
• Field of Search: None
• CPC Class Codes: A61B 2017/320069 for ablating tissue
• CPC Class Codes: A61B 2017/32007 with suction or vacuum means
• CPC Class Codes: A61B 2017/320071 with articulating means for working tip
• CPC Class Codes: A61B 2017/320078 Tissue manipulating surface
• CPC Class Codes: A61B 2018/00291 using suction
• CPC Class Codes: A61B 2034/2051 Electromagnetic tracking systems
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2090/3782 transmitter or receiver in catheter or minimal invasive instrument
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 8/4281 characterised by sound-transmitting media or devices for coupling the transducer to the tissue
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.

Claims

1. An ablation device for ablating tissue within a patient, comprising:

a two-dimensional array of transducer elements including a plurality of transducer elements, the two-dimensional array of transducer elements configured to deliver high intensity focused ultrasound (HIFU) energy, wherein the transducer elements have a taper and further wherein the transducer elements positioned more centrally in the two-dimensional array are larger than the transducer elements positioned more peripherally in the two-dimensional array.

2. The ablation device of claim 1, wherein the taper comprises a gradual reduction in size of the transducer elements from a center of the two-dimensional array to a periphery of the two-dimensional array.

3. The ablation device of claim 1, wherein the taper is configured such that high intensity focused ultrasound (HIFU) energy delivered from the two-dimensional array is at least approximately three decibels greater intensity at a focus zone in comparison to a grating lobe.

4. The ablation device of claim 1, wherein each of the transducer elements has an approximately equal impedance to each other ones of the transducer elements.

5. The ablation device of claim 4, further comprising an impedance match circuit operatively coupled to the transducer elements and providing, at least in part, the approximately equal impedance of each of the transducer elements to each other ones of the transducer elements.

6. The ablation device of claim 5, wherein the impedance is approximately fifty ohms at a temperature of zero degrees centigrade.

7. The ablation device of claim 4, further comprising:

an acoustic membrane having an acoustic impedance and positioned with respect to the two-dimensional array; and

a fluid contained within the ablation device, at least in part, by the acoustic membrane, the fluid having a fluid impedance;

wherein the acoustic impedance of the acoustic membrane is approximately equal to the acoustic impedance of the fluid.

8. The ablation device of claim 7, wherein the acoustic membrane is comprised of a material having a thickness, the thickness of the acoustic membrane being a function of a difference between a speed of sound through the material and a speed of sound through the fluid to reduce a refraction of said high intensity focused ultrasound (HIFU) energy through the material.

9. The ablation device of claim 1:

wherein the two-dimensional array further comprises a number of grid elements and wherein the two-dimensional array has a number of the transducer elements;

wherein the transducer elements of the two-dimensional array are spatially sparse due to the number of grid elements being greater than the number of transducer elements.

10. The ablation device of claim 1, wherein the two-dimensional array of transducer elements is a two-dimensional phased array of transducer elements.

11. A method for ablating tissue of a patient, comprising:

delivering high intensity focused ultrasound (HIFU) energy from a two-dimensional array of transducer elements to tissue of the patient, wherein the two-dimensional array of transducer elements includes a plurality of transducer elements, the two-dimensional array of transducer elements having a taper and further wherein the transducer elements positioned more centrally in the two-dimensional array are larger than the transducer elements positioned more peripherally in the two-dimensional array.

12. The method of claim 11, wherein the high intensity focused ultrasound (HIFU) energy delivered from the two-dimensional array of transducer elements is at least approximately three decibels greater intensity at a focus zone in comparison with a grating lobe.

13. The method of claim 11, wherein each transducer element of the two-dimensional array of transducer elements is independently actuatable, and wherein the focusing step comprises independently actuating each transducer element.

14. The method of claim 11, wherein the delivering high intensity focused ultrasound (HIFU) energy to tissue of the patient includes focusing the high intensity focused ultrasound (HIFU) energy to a focus zone at a predetermined distance from the array of transducer elements.

15. The method of claim 11, wherein each of the transducer elements has an approximately equal impedance to each other ones of the transducer elements.

16. The method of claim 11, wherein each transducer element of the two-dimensional array of transducer elements is selectively actuatable to allow for electronic steering of the high intensity focused ultrasound (HIFU) energy.

17. The method of claim 11, wherein the taper comprises a gradual reduction in size of the transducer elements from a center of the two-dimensional array to a periphery of the two-dimensional array.

18. The method of claim 11, wherein the two-dimensional array of transducer elements is a two-dimensional phased array of transducer elements.

19. The method of claim 11:

wherein the two-dimensional array further comprises a number of grid elements and wherein the two-dimensional array has a number of the transducer elements;

wherein the transducer elements of the two-dimensional array are spatially sparse due to the number of grid elements being greater than the number of transducer elements.