Delivering ocular implants into the eye

• US 9,931,243 B2
• Filed: 01/08/2015
• Issued: 04/03/2018
• Est. Priority Date: 12/19/2011
• Status: Active Grant

• Current Assignee: Alcon Incorporated
• Original Assignee: Ivantis Inc. (Alcon Incorporated)
• Inventors: Wardle, John, Schieber, Andrew T.
• Primary Examiner(s): Zalukaeva, Tatyana
• Assistant Examiner(s): Zimbouski, Ariana
• Application Number:
  US14/592,703
• Publication Number:
  US 20150119787A1
• Time in Patent Office: 1,181 Days
• CPC Class Codes: A61B 17/3421 Cannulas
• CPC Class Codes: A61B 17/3468 for implanting or removing devices, e.g. prostheses, implants, seeds, wires devices for implanting seeds A61M37/0069
• CPC Class Codes: A61B 2017/3454 Details of tips
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/0026 Ophthalmic product dispenser attachments to facilitate positioning near the eye
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

A method of deploying an ocular implant into Schlemm'"'"'s canal of an eye. The method includes the steps of inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula having a distal opening extending from the distal end and through a side wall; placing the distal opening of the cannula into fluid communication with Schlemm'"'"'s canal; advancing the ocular implant distally through the cannula with a delivery tool engaged with the ocular implant, a proximal portion of the ocular implant engaging the delivery tool proximal to a distal portion of the delivery tool; and disengaging the ocular implant and the delivery tool when the proximal portion of the ocular implant reaches the cannula distal opening. The invention also includes a system for practicing the method.

Claims

1. A method of deploying an ocular implant into Schlemm'"'"'s canal of an eye, the method comprising:

inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula comprising a side wall defining a passageway, an opening in fluid communication with the passageway and extending through the side wall and a distal end of the cannula to define a trough having a depth dimension deeper than a width of the ocular implant, and a distal opening surface surrounding the opening;

inserting a distal end of the trough through trabecular meshwork into Schlemm'"'"'s canal to place the opening of the cannula in fluid communication with Schlemm'"'"'s canal;

advancing the ocular implant distally through the cannula into Schlemm'"'"'s canal without the ocular implant intersecting the trabecular meshwork; and

a disengaging step comprising disengaging interlocking portions of the ocular implant and the delivery tool when a portion of the ocular implant is in Schlemm'"'"'s canal and when the interlocking portions are in the trough.

2. The method of claim 1 wherein the cannula comprises a bevel at the distal end of the trough, the method further comprising inserting the bevel into Schlemm'"'"'s canal.

3. The method of claim 1 wherein the advancing step further comprises placing a distal end of the ocular implant in Schlemm'"'"'s canal while a proximal end of the ocular implant is within the cannula proximal to the trough.

4. The method of claim 1 wherein the disengaging step comprises a moving step comprising moving the delivery tool away from the ocular implant.

5. The method of claim 4 wherein the moving step comprises permitting the delivery tool to move toward a curved at-rest position.

6. The method of claim 1 further comprising:

a reengaging step comprising reengaging the ocular implant and the delivery tool after the disengaging step.

7. The method of claim 6 further comprising moving the ocular implant proximally after the reengaging step.

8. A method of deploying an ocular implant into Schlemm'"'"'s canal of an eye, the method comprising:

inserting a distal end of a cannula through a cornea of the eye and into an anterior chamber of the eye, the cannula comprising a side wall defining a passageway, an opening in fluid communication with the passageway and extending through the side wall and a distal end of the cannula to define a trough, and a distal opening surface surrounding the opening;

inserting a distal end of the trough through trabecular meshwork into Schlemm'"'"'s canal to place a distal portion of the opening of the cannula in fluid communication with Schlemm'"'"'s canal;

an advancing step comprising advancing the ocular implant distally through the cannula into Schlemm'"'"'s canal with a delivery tool while a proximal portion of the opening remains open to the anterior chamber; and

a disengaging step comprising disengaging interlocking portions of the ocular implant and the delivery tool when a portion of the ocular implant is in Schlemm'"'"'s canal and when the interlocking portions are in the proximal portion of the opening.

9. The method of claim 8 wherein the advancing step comprises advancing the ocular implant distally through the cannula into Schlemm'"'"'s canal while a proximal portion of the opening remains open to the anterior chamber.

10. The method of claim 8 wherein the cannula comprises a bevel at the distal end of the trough, the method further comprising inserting the bevel into Schlemm'"'"'s canal.

11. The method of claim 8 wherein the advancing step further comprises placing a distal end of the ocular implant in Schlemm'"'"'s canal while a proximal end of the ocular implant is within the cannula proximal to the trough.

12. The method of claim 8 further comprising a reengaging step comprising reengaging the ocular implant and the delivery tool after the disengaging step.

13. The method of claim 12 further comprising moving the ocular implant proximally after the reengaging step.