Method for treating cerebral amyloid angiopathy using pharmacological chaperones to increase the activity of gangliosidases
First Claim
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1. A method for the treatment of Cerebral Amyloid Angiopathy in an individual, comprising administering to the individual an effective amount of a pharmacological chaperone, wherein the pharmacological chaperone is selected from 2-acetamido-1,2-dideoxynojirimycin and N-acetyl-glucosamine-thiazoline.
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Abstract
The present invention relates to a method for treating an individual having Cerebral Amyloid Angiopathy by using pharmacological chaperones to increase the activity of gangliosidase and/or sialidase enzymes involved in ganglioside catabolism.
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6 Claims
- 1. A method for the treatment of Cerebral Amyloid Angiopathy in an individual, comprising administering to the individual an effective amount of a pharmacological chaperone, wherein the pharmacological chaperone is selected from 2-acetamido-1,2-dideoxynojirimycin and N-acetyl-glucosamine-thiazoline.
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