Devices and methods for vascular recanalization
First Claim
1. A method of treating an embolism comprising:
- delivering an embolectomy device to an embolism that at least, partially restricts blood flow through a blood vessel, wherein the embolectomy device comprises an expandable member having a first expandable portion, a second expandable portion, and a third expandable portion, each of the first expandable portion, the second expandable portion, and the third expandable portion comprising a mesh, the meshes of the first expandable portion and the third expandable portion having a first mesh density, the mesh of the second expandable portion having a second mesh density, the second mesh density being less than the first mesh density when the first expandable portion, the second expandable portion, and the third expandable portion are expanded to the same extent, wherein at least a portion of the expandable member is configured to expand outwardly to engage at least a portion of the embolism or blood vessel wall;
deploying the embolectomy device within the embolism so as to restore blood flow through the embolism and, form a flow channel through the embolism while the expandable member of the embolectomy device is expanded, wherein the embolectomy device in a deployed configuration comprises first and third portions expanded to a greater extent than the second portion, the second expandable portion being disposed between the first and third expandable portions, and wherein the first and third expandable portions project radially outward beyond the second portion;
moving the embolectomy device and at east a portion of the embolism along the blood vessel; and
withdrawing the embolectomy device and at least a portion of the embolism from the blood vessel.
3 Assignments
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Accused Products
Abstract
In some embodiments, a medical device for recanalizing a vessel having a blockage and restoring blood flow through an obstructed blood vessel includes an expandable member coupled to a core wire and a hypotube that are movable relative to each other to manipulate the expandable member between various configurations. The expandable member having a capture structure in an expanded configuration. The expandable member can include multiple interstices formed by woven mesh filaments or braided strands through which the material blocking the vessel can pass. The capture structure can include a shape on its external surface that facilitates dislodgement and capture of the material within capture spaces created by the expandable member. Some embodiments include a capture sack or cap for capturing material and preventing material from migrating down stream of the blockage. Superoxygenated blood can be infused distal to the blockage to minimize loss of function during an ischemic event.
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Citations
17 Claims
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1. A method of treating an embolism comprising:
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delivering an embolectomy device to an embolism that at least, partially restricts blood flow through a blood vessel, wherein the embolectomy device comprises an expandable member having a first expandable portion, a second expandable portion, and a third expandable portion, each of the first expandable portion, the second expandable portion, and the third expandable portion comprising a mesh, the meshes of the first expandable portion and the third expandable portion having a first mesh density, the mesh of the second expandable portion having a second mesh density, the second mesh density being less than the first mesh density when the first expandable portion, the second expandable portion, and the third expandable portion are expanded to the same extent, wherein at least a portion of the expandable member is configured to expand outwardly to engage at least a portion of the embolism or blood vessel wall; deploying the embolectomy device within the embolism so as to restore blood flow through the embolism and, form a flow channel through the embolism while the expandable member of the embolectomy device is expanded, wherein the embolectomy device in a deployed configuration comprises first and third portions expanded to a greater extent than the second portion, the second expandable portion being disposed between the first and third expandable portions, and wherein the first and third expandable portions project radially outward beyond the second portion; moving the embolectomy device and at east a portion of the embolism along the blood vessel; and withdrawing the embolectomy device and at least a portion of the embolism from the blood vessel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method of treating an embolism comprising:
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accessing a vessel of a patient; delivering a clot treatment device to a clot of an embolism that at least partially restricts blood flow through a blood vessel with a delivery catheter, wherein the clot treatment device comprises an expandable member having a first portion with a first outer perimeter, a second portion with a second outer perimeter, and a third portion with a third outer perimeter, each of the first portion, the second portion, and the third portion comprising a mesh, the meshes of the first portion and the third portion having a first mesh density, the mesh of the second portion having a second mesh density, the second mesh density being less than the first mesh density when the first portion, the second portion, and the third portion are expanded to the same extent, wherein the second portion is disposed between the first and third portions, and wherein at least a portion of the expandable member is configured to expand outwardly to engage at least a portion of the embolism or blood vessel wall; positioning the clot treatment device within the embolism; radially expanding the expandable member against the clot so as to restore blood flow through the clot in the blood vessel while the expandable member of the clot treatment device is expanded, wherein the clot treatment device in a deployed configuration comprises first and third portions expanded to a greater extent than the second portion, and wherein the second outer perimeter is smaller than the first and third outer perimeters such that the expandable member defines at least one capture region between the first and third outer perimeters; disrupting at least a portion of the clot with the at least one capture region of expandable member; retrieving at least a portion of the clot with the at least one capture region of the expandable member; and withdrawing the clot treatment device and at least a portion of the clot from the blood vessel. - View Dependent Claims (16, 17)
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Specification