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Labeled enzyme compositions, methods and systems

  • US 9,932,573 B2
  • Filed: 01/09/2017
  • Issued: 04/03/2018
  • Est. Priority Date: 03/27/2009
  • Status: Active Grant
First Claim
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1. A method for creating a labeled polymerase conjugate, comprising:

  • linking a polymerase to at least three optically-detectable dye labels to form a labeled polymerase conjugate having polymerase activity and the at least three dye labels linked to the polymerase,wherein the polymerase includes a biotin ligase modification site, and the linking comprises linking a biotin moiety to the polymerase to produce a biotinylated polymerase.

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