Impedance based anatomy generation

• US 9,936,922 B2
• Filed: 08/24/2015
• Issued: 04/10/2018
• Est. Priority Date: 05/08/2009
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Harlev, Doron, Csendes, Alpar, Badics, Zsolt
• Primary Examiner(s): HINDENBURG, MAX F
• Application Number:
  US14/834,211
• Publication Number:
  US 20160051204A1
• Time in Patent Office: 960 Days
• CPC Class Codes: A61B 2562/04 Arrangements of multiple sensors of the same type
• CPC Class Codes: A61B 5/0044 for the heart
• CPC Class Codes: A61B 5/0536 Impedance imaging, e.g. by tomography
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 5/4869 Determining body composition
• CPC Class Codes: A61B 5/6858 with a distal basket, e.g. expandable basket
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 6/503 for diagnosis of the heart
• CPC Class Codes: A61B 8/0883 for diagnosis of the heart

Abstract

Methods and systems for the determination and representation of anatomy anatomical information are disclosed herein.

Claims

1. A method comprising:

inserting a catheter into a heart, the catheter comprising three or more electrodes;

causing the catheter to move to each of multiple, different positions in the heart;

for each of the multiple, different catheter positions, causing current flow between at least some of the electrodes and measuring electrical signals, from the current flow, at each of one or more of the electrodes; and

determining anatomical information about the heart based on positions of the electrodes and based on complex impedance information determined from the electrical signals measured at the different catheter positions.

2. The method of claim 1, wherein the complex impedance information is based on a permittivity contrast between homogenous and non-homogenous media.

3. The method of claim 1, wherein the complex impedance information is based on a first permittivity inside a cardiac chamber boundary and a second permittivity outside the cardiac chamber boundary.

4. The method of claim 1, wherein determining the anatomical information comprises detecting a boundary of the heart by detecting a surface at which the permittivity changes.

5. The method of claim 1, comprising:

displaying at least a portion of the anatomical information.

6. The method of claim 1, comprising;

displaying distances between at least some of the electrodes and a surface at which the permittivity changes.

7. The method of claim 1, wherein determining anatomical information about the heart comprises:

determining closed surfaces around at least one portion of the catheter based on the electrical signals measured at the one or more of the electrodes.

8. The method of claim 7, wherein portions of the closed surfaces represent the boundary of the heart.

9. A method comprising:

inserting a catheter into a heart, the catheter comprising three or more electrodes;

causing the catheter to move to each of multiple, different positions in the heart;

for each of the multiple, different catheter positions, causing current flow between at least some of the electrodes and measuring electrical signals, from the current flow, at each of one or more of the electrodes; and

determining anatomical information about the heart by detecting variations in complex impedance information determined from the electrical signals measured at the different catheter positions, the variations based on an inhomogeneous distribution of material due to anatomical features of the heart.

10. The method of claim 9, wherein determining the anatomical information comprises:

accounting for a first permittivity inside a cardiac chamber boundary and a second permittivity outside the cardiac chamber boundary.

11. The method of claim 9, wherein determining the anatomical information comprises:

detecting a boundary of the heart by detecting a surface at which the permittivity changes.

12. The method of claim 9, comprising;

displaying distances between at least some of the electrodes and a surface at which the permittivity changes.

13. The method of claim 9, wherein determining the anatomical information comprises:

distinguishing electrical signals indicative of cardiac electrical activity from the electrical signals based on the current flow; and

determining the anatomical information based on the electrical signals based on the current flow.

14. A system comprising:

a catheter comprising multiple, spatially distributed electrodes including one or more electrodes configured to inject a current and to measure electrical signals in response to the injected current;

a system configured to determine a position of the electrodes at multiple, different catheter positions; and

a processing unit configured to determine anatomical information about the heart based on positions of the electrodes and based on complex impedance information determined from the electrical signals measured at the different catheter positions.

15. The system of claim 14, wherein the complex impedance information is based on a permittivity contrast between homogenous and non-homogenous media.

16. The system of claim 14, wherein the complex impedance information is based on a first permittivity inside a cardiac chamber boundary and a second permittivity outside the cardiac chamber boundary.

17. The system of claim 14, wherein the processing unit is configured to detect a boundary of the heart by detecting a surface at which the permittivity changes.

18. The system of claim 14, comprising a display, wherein the processing unit is configured to display at least a portion of the anatomical information on the display.

19. The system of claim 14, comprising a display, wherein the processing unit is configured to display distances between at least some of the electrodes and a surface at which the permittivity changes, on the display.

20. The system of claim 14, wherein the processing unit is configured to:

determine physiological information at multiple locations of a boundary of the heart based on the determined positions of the electrodes and the electrical signals measured at the different catheter positions; and

display at least a portion of the anatomical information and at least a portion of the physiological information.