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Ocular insert apparatus and methods

  • US 9,937,073 B2
  • Filed: 01/20/2015
  • Issued: 04/10/2018
  • Est. Priority Date: 06/01/2010
  • Status: Active Grant
First Claim
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1. An ocular insert for delivering at least one therapeutic agent to an eye for an extended period of time, the insert comprising:

  • a supporting skeletal structure forming at least an arc of an annulus, the skeletal structure configured to be positioned on the eye outside the cornea of the eye and at least partially underneath at least one of the upper and lower eyelids;

    an outer structure encapsulating at least a first portion of the skeletal structure along the arc, the outer structure supported by the skeletal structure, wherein the outer structure is of a durometer that is lower than a durometer of the skeletal structure; and

    at least one therapeutic agent provided by the ocular insert;

    wherein the ocular insert has a first shape prior to being positioned onto the eye, and the ocular insert conforms in situ after being positioned onto the eye for a period of time, and wherein, upon being removed from the eye, the ocular insert maintains a second shape that is different from the first shape, wherein the skeletal structure determines the first shape and the second shape of the ocular insert.

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