Shaped occluding devices and methods of using the same

• US 9,943,427 B2
• Filed: 11/06/2012
• Issued: 04/17/2018
• Est. Priority Date: 11/06/2012
• Status: Active Grant

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Covidien LP (Medtronic Plc)
• Inventors: Losordo, Michael Louis, Molaei, Masoud
• Primary Examiner(s): Lopez, Leslie
• Application Number:
  US13/669,944
• Publication Number:
  US 20140128957A1
• Time in Patent Office: 1,988 Days
• Field of Search: 623 12, 623 13- 131, 623 134, 623 153
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2002/068 Modifying the blood flow model, e.g. by diffuser or deflector
• CPC Class Codes: A61F 2002/823 Stents, different from stent-grafts, adapted to cover an aneurysm
• CPC Class Codes: A61F 2230/008 paraboloidal

Abstract

A self-expanding stent includes a proximal portion having a first cross-sectional area in an expanded state, a distal portion having a second cross-sectional area in an expanded state, a narrowed portion between the proximal portion and the distal portion, the narrowed portion comprising a cross-sectional area when in an expanded state that is less than the first cross-sectional area and the second cross-sectional area, wherein the narrowed portion is configured to increases flow velocity in the narrowed portion while reducing reduce pressure against a distal wall of the aneurysm by being axially disposed substantially between a proximal edge and a distal edge of an aneurysm neck or ostium, the flow traversing through the lumen of the self-expanding stent. In use, the self-expanding stent is positioned at the site of an aneurysm and expanded via release from a stent delivery device.

Claims

1. A self-expanding braided stent comprising:

a proximal portion formed by a plurality of helically braided filaments, wherein when the stent is in an expanded, pre-shaped state the proximal portion has a first central longitudinal axis and a first cross-sectional area;

a distal portion formed by the plurality of helically braided filaments, wherein when the stent is in the expanded, pre-shaped state the distal portion has a second central longitudinal axis and a second cross-sectional area; and

a narrowed portion between the proximal portion and the distal portion, the narrowed portion formed by the plurality of helically braided filaments, wherein when the stent is in the expanded, pre-shaped state the narrowed portions has a third central longitudinal axis and a third cross-sectional area that is less than the first cross-sectional area and the second cross-sectional area,

wherein when the stent is in the expanded, pre-shaped state;

the narrowed portion comprises a porosity defined by the plurality of helically braided filaments that is lower than a porosity of the proximal portion and a porosity of the distal portion,

the first and the second central longitudinal axes are axially aligned and the third central longitudinal axis is axially offset from the first and the second central longitudinal axes,

the proximal portion has a uniform diameter along a first length extending from a first end of the stent to the narrowed portion, and

the distal portion has a uniform diameter along a second length extending from a second end of the stent to the narrowed portion.

2. The self-expanding stent of claim 1, wherein the narrowed portion of the stent is configured to reduce flow against a distal wall of an aneurysm of a body vessel.

3. The self-expanding stent of claim 1, wherein the first cross-sectional area is larger than the second cross-sectional area.

4. The self-expanding stent of claim 3, wherein the first cross-sectional area is selected to allow the stent to protrude into an aneurysm of a body vessel when the stent is expanded in the body vessel.

5. The self-expanding stent of claim 1, wherein the first cross-sectional area and the second cross-sectional area are equal.

6. The self-expanding stent of claim 1, wherein the proximal portion comprises an intermediate portion formed by the plurality of helically braided filaments, and wherein when the stent is expanded within a body vessel across an ostium of an aneurysm:

(1) the intermediate portion comprises a fourth cross-sectional area greater than any other cross-sectional area of the stent outside the intermediate portion and (2) at least some of the intermediate portion does not contact the body vessel.

7. The self-expanding stent of claim 1, wherein the narrowed portion further comprises a coating.

8. The self-expanding stent of claim 1, further comprising a radio opaque marker disposed at a proximal end of the distal portion where the self-expanding stent transitions to the narrowed portion.

9. The self-expanding stent of claim 1, wherein the first cross-sectional area and the second cross-sectional area are circular, and wherein the first cross-sectional area has a first diameter and the second cross-sectional area has a second diameter.

10. The self-expanding stent of claim 9, wherein the narrowed portion has a greatest cross-sectional dimension less than the first diameter and the second diameter.

11. The self-expanding stent of claim 1, wherein the narrowed portion is configured such that when the stent is expanded within a body vessel across an ostium of an aneurysm, at least some of the narrowed portion does not contact the body vessel.

12. A system comprising:

a self-expanding stent comprising;

a proximal portion, wherein when the stent is in an expanded, pre-shaped state the proximal portion has a first central longitudinal axis and a first cross-sectional area;

a distal portion, wherein when the stent is in the expanded, pre-shaped state the distal portion has a second central longitudinal axis and a second cross-sectional area; and

a narrowed portion between the proximal portion and the distal portion, wherein when the stent is in the expanded, pre-shaped state the narrowed portion has a third central longitudinal axis and a third cross-sectional area that is less than the first cross-sectional area and the second cross-sectional area,

wherein the stent is formed of a plurality of braided filaments extending along an entire length of the stent,

wherein when the stent is in the expanded, pre-shaped state;

the narrowed portion comprises a porosity defined by the braided filaments that is lower than a porosity of the proximal portion and a porosity of the distal portion,

the first and the second central longitudinal axes are axially aligned and the third central longitudinal axis is axially offset from the first and the second central longitudinal axes,

the proximal portion has a uniform diameter along a first length extending from a first end of the stent to the narrowed portion, and

the distal portion has a uniform diameter along a second length extending from a second end of the stent to the narrowed portion; and

a stent delivery device configured to position and release the self-expanding stent.

13. The system of claim 12, wherein the first cross-sectional area is larger than the second cross-sectional area.

14. The system of claim 13, wherein the first cross-sectional area is selected to allow the stent to protrude into an aneurysm of a body vessel when the stent is expanded in the body vessel.

15. The system of claim 12, wherein the first cross-sectional area and the second cross-sectional area are equal.

16. The system of claim 12, wherein the proximal portion comprises an intermediate portion, and wherein when the stent is expanded within a body vessel across an ostium of an aneurysm:

(1) the intermediate portion comprises a fourth cross-sectional area greater than any other cross-sectional area of the stent outside the intermediate portion and (2) at least some of the intermediate portion does not contact the body vessel.

17. The system of claim 12, wherein the narrowed portion further comprises a coating.

18. The system of claim 12, wherein the self-expanding stent further comprises a radio opaque marker disposed at a proximal end of the distal portion where the self-expanding stent transitions to the narrowed portion.

19. The system of claim 12, wherein the first cross-sectional area and the second cross-sectional area are circular, and wherein the first cross-sectional area has a first diameter and the second cross-sectional area has a second diameter.

20. The system of claim 19, wherein the narrowed portion has a greatest cross-sectional dimension less than the first diameter and the second diameter.

21. The system of claim 12, wherein the narrowed portion is configured such that when the stent is expanded within a body vessel across an ostium of an aneurysm, at least some of the narrowed portion does not contact the body vessel.