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Systems, devices, components and methods for triggering or inducing resonance or high amplitude oscillations in a cardiovascular system of a patient

  • US 9,943,461 B1
  • Filed: 02/27/2013
  • Issued: 04/17/2018
  • Est. Priority Date: 02/29/2012
  • Status: Active Grant
First Claim
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1. A system configured to provide vibration stimulation therapy to a patient, comprising:

  • a plurality of sensors that are adapted to be attached to the patient, wherein the plurality of sensors continuously monitor a plurality of physiological parameters of the patient, wherein the plurality of physiological parameters include power spectral density consecutive R-wave to R-wave interval data of a cardiovascular system of the patient;

    a vibration signal generator that is adapted to be attached to a region of the patient and that is configured to deliver one or more vibration signals to the region of the patient, wherein the vibration signal generator includes a vibration motor;

    a hardware processor operably connected to the vibration signal generator and the plurality of sensors, wherein the hardware processor is configured to;

    determine a resonance frequency from a plurality of resonance frequencies including one or more of heart rate, blood pressure, vascular tone, and stroke volume of the cardiovascular system of the patient;

    determine vibration signal parameters for a baseline vibration signal to deliver to the region of the patient based on the determined resonance frequency of the cardiovascular system of the patient from the plurality of physiological parameters obtained from the plurality of sensors adapted to be attached to the patient at a first time, wherein the baseline vibration signal parameters includes a baseline waveform shape, a baseline amplitude, and a baseline frequency that includes a first time period associated with a first type of baseline vibration signal and a second time period associated with a second type of baseline vibration signal, wherein a combination of the first time period and the second time period is equivalent to a third time period and wherein the third time period is set to approximate the determined resonance frequency of the cardiovascular system of the patient;

    cause the power spectral density consecutive R-wave to R-wave interval data of the patient to be modified by transmitting the determined vibration signal parameters to the vibration motor in the vibration signal generator and delivering the baseline vibration signal having the baseline waveform shape, the baseline amplitude, and the baseline frequency to the region of the patient;

    determine whether the power spectral density consecutive R-wave to R-wave interval data of the patient at a second time is deemed as inducing resonance or high amplitude oscillations in the cardiovascular system of the patient by (i) determining a frequency range based on a single-cycle duration of time corresponding to the sum of a first duration of time associated with the first time periods and a second duration of time associated with the second time period and (ii) determining whether a peak is present within the determined frequency range of the power spectral density consecutive R-wave to R-wave interval data of the patient;

    in response to determining that the power spectral density consecutive R-wave to R-wave interval data of the patient at the second time is not deemed as inducing resonance or high amplitude oscillations in the cardiovascular system of the patient, determine adjusted vibration signal parameters based on the plurality of physiological parameters obtained from the plurality of sensors adapted to be attached to the patient at the second time, wherein the adjusted vibration signal parameters includes at least one of an adjusted waveform shape, an adjusted amplitude, and an adjusted frequency that includes a fourth time period associated with a first type of adjusted vibration signal and a fifth time period associated with a second type of adjusted vibration signal, wherein a combination of the fourth time period and the fifth time period is equivalent to the third time period that approximates the determined resonance frequency of the cardiovascular system of the patient; and

    transmit the adjusted vibration signal parameters to the vibration motor in the vibration signal generator, thereby delivering an adjusted vibration signal having the adjusted vibration signal parameters to the region of the patient.

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