Medical devices including vial adapter with inline dry drug module

• US 9,943,463 B2
• Filed: 05/05/2014
• Issued: 04/17/2018
• Est. Priority Date: 05/10/2013
• Status: Active Grant

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: Marks, Hugh Zachary, Lev, Nimrod, Lev, Amir
• Primary Examiner(s): Wiest, Philip R
• Application Number:
  US14/888,590
• Publication Number:
  US 20160081878A1
• Time in Patent Office: 1,443 Days
• Field of Search: 604403-416
• CPC Class Codes: A61J 1/201 having one piercing end
• CPC Class Codes: A61J 1/2075 for external venting
• CPC Class Codes: A61J 1/2082 for gas filtration
• CPC Class Codes: A61J 1/2096 Combination of a vial and a syringe for transferring or mixing their contents
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing

Abstract

Medical devices including a vial adapter with an inline dry drug module for use with a vial, a needleless syringe and a carrier liquid for filling the needleless syringe with an injection solution for injection to a patient. The inline dry drug modules include a dry drug storage component for storing a dry drug dosage and a uniform carrier liquid distribution component for promoting uniform contact of the dry drug storage component by the carrier liquid to form an injection solution from the dry drug dosage. The inline dry drug modules can include a discrete dry drug storage component and a discrete uniform carrier liquid distribution component or a dual purpose component for both drug storage and uniform carrier liquid distribution. The vial adapters can be provided in vented or non-vented versions.

Claims

1. A medical device for use with a needleless syringe, a vial and a carrier liquid for filling the needleless syringe with an injection solution for injection to a patient, the needleless syringe having a male connector, the vial having a vial stopper and a vial interior, the medical device having a longitudinal device axis and comprising:

(a) a vial adapter having a skirt with downward depending flex members for telescopic mounting on the vial, a puncturing cannula for puncturing the vial stopper on said telescopic mounting for flow communication with the vial interior and a central upright female connector in flow communication with said puncturing cannula and intended for connection to the male connector;

characterized by

(b) an inline dry drug module disposed inline between said female connector and said puncturing cannula, said inline dry drug module including a dry drug storage component storing a dry drug dosage and a uniform carrier liquid distribution component for promoting uniform contact of said dry drug storage component by said carrier liquid on aspiration of carrier liquid from the vial through the inline dry drug module directly to the needleless syringe to form the injection solution.

2. The device according to claim 1, wherein said inline dry drug module includes a discrete dry drug storage component for storing said dry drug dosage and a discrete uniform carrier liquid distribution component for promoting said uniform contact.

3. The device according to claim 1, wherein said inline dry drug module includes a dual purpose component for both storing said dry drug dosage and promoting said uniform contact.

4. The device according to claim 3, wherein the uniform carrier liquid component includes a uniform carrier liquid component topside facing said female connector, a uniform carrier liquid distribution component underside facing said puncturing cannula and a uniform carrier liquid distribution component peripheral edge,

wherein said uniform carrier liquid distribution component topside has a dry drug dosage coating constituting the dry drug storage component.

5. The device according to claim 4, wherein the uniform carrier liquid distribution component underside is formed with a series of radial grooves each terminating at the cutout in the uniform carrier liquid distribution component peripheral edge for enabling flow communication from the uniform carrier liquid distribution component underside to the uniform carrier liquid distribution component topside on aspiration of the needleless syringe to draw liquid contents from the vial through the inline dry drug module directly to the needleless syringe.

6. The device according to claim 1, wherein said, uniform carrier liquid component includes a uniform carrier liquid component topside facing said female connector, a uniform carrier liquid distribution component underside facing said puncturing cannula and a uniform carrier liquid distribution component peripheral edge,

said uniform carrier liquid distribution component underside having a multitude of radial grooves each terminating in a cutout in said uniform carrier liquid distribution component peripheral edge thereby enabling carrier liquid to flow from said uniform carrier liquid distribution component underside to said uniform carrier liquid distribution component topside on aspiration of the needleless syringe to draw liquid contents from the vial through the inline dry drug module directly to the needleless syringe.