System and method to automatically maintain electrical stimulation intensity

• US 9,943,694 B2
• Filed: 05/11/2016
• Issued: 04/17/2018
• Est. Priority Date: 10/26/2006
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Thacker, James R., Haut, Harold, Nathan, Robert, Peterson, David K. L., Bradley, Kerry
• Primary Examiner(s): LEVICKY, WILLIAM J
• Application Number:
  US15/152,336
• Publication Number:
  US 20160250489A1
• Time in Patent Office: 706 Days
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36146 specified by the stimulation parameters
• CPC Class Codes: A61N 1/36171 Frequency
• CPC Class Codes: A61N 1/36175 Pulse width or duty cycle
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

Tissue stimulation systems generally include a pulse generating device for generating electrical stimulation pulses, at least one implanted electrode for delivering the electrical stimulation pulses generated by the pulse generating device, and a programmer capable of communicating with the pulse generating device. Stimulation pulses may be defined by several parameters, such as pulse width and amplitude. In methods of stimulating the tissue with the stimulation system, a user may adjust one of the parameters such as pulse width. The programmer may automatically adjust the pulse amplitude in response to the change in pulse width in order to maintain a substantially constant effect of the stimulation pulses.

Claims

1. A system, comprising:

a programmer configured to instruct a stimulator to deliver electrical current to at least one electrode that is in contact with tissue of a patient to provide an effect, wherein;

the electrical current is representable using a current-time curve; and

adjustable stimulation parameters are used to define the electrical current including an area under the current-time curve that reflects a total charge transfer over a time period which causes the effect of the electrical current;

wherein the programmer is configured to automatically respond to a manual adjustment of at least a first one of the stimulation parameters by automatically adjusting at least a second of the stimulation parameters to maintain the total charge transfer by maintaining the area under the current-time curve over the time period.

2. The system of claim 1, wherein the controller is configured to automatically respond to a manual adjustment of an amplitude by automatically adjusting a pulse width to maintain the total charge transfer by maintaining the area under the current-time curve over the time period.

3. The system of claim 1, wherein the controller is configured to automatically respond to a manual adjustment of a pulse width by automatically adjusting an amplitude to maintain the total charge transfer by maintaining the area under the current-time curve over the time period.

4. The system of claim 1, wherein:

the stimulator is configured to deliver pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude; and

the controller is configured to automatically respond to a manual adjustment of a pulse frequency by automatically adjusting both the amplitude and the pulse width.

5. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to:

instruct a stimulator to deliver electrical current to at least one electrode that is in contact with tissue of a patient to provide an effect, wherein;

the electrical current is representable using a current-time curve; and

adjustable stimulation parameters are used to define the electrical current including an area under the current-time curve that reflects a total charge transfer over a time period which causes the effect of the electrical current; and

automatically respond to a manual adjustment of at least a first one of the stimulation parameters by automatically adjusting at least a second of the stimulation parameters to maintain the total charge transfer by maintaining the area under the current-time curve over the time period.

6. The non-transitory machine-readable medium of claim 5, wherein the automatically respond includes automatically respond to an adjustment of an amplitude by automatically adjusting a pulse width to maintain the total charge transfer by maintaining the area under the current-time curve over the time period.

7. The non-transitory machine-readable medium of claim 5, wherein the automatically respond includes automatically respond to an adjustment of a pulse width by automatically adjusting an amplitude to maintain the total charge transfer by maintaining the area under the current-time curve over the time period.

8. The non-transitory machine-readable medium of claim 5, wherein:

the deliver electrical current includes deliver pulsed electrical current that has pulses and that has a pulse frequency and an amplitude; and

the automatically respond includes automatically respond to an adjustment of a pulse frequency by automatically adjusting the amplitude.

9. The non-transitory machine-readable medium of claim 5, wherein:

the deliver electrical current includes deliver pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency; and

the automatically respond includes automatically respond to an adjustment of a pulse frequency by automatically adjusting the pulse width.

10. The non-transitory machine-readable medium of claim 5, wherein:

the deliver electrical current includes deliver pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude; and

the automatically respond includes automatically respond to an adjustment of a pulse frequency by automatically adjusting both the amplitude and the pulse width.

11. The non-transitory machine-readable medium of claim 5, wherein the at least the first of the stimulation parameters or the at least the second of the stimulation parameters includes a pulse rise time, or a pulse fall time, or both the pulse rise time and the pulse fall time.

12. A method, comprising:

delivering electrical current to at least one electrode that is in contact with tissue of a patient to provide an effect, wherein;

the delivered electrical current is representable using a current-time curve; and

adjustable stimulation parameters are used to define the delivered electrical current including an area under the current-time curve that reflects a total charge transfer over a time period which causes the effect of the delivered electrical current; and

adjusting at least a first one of the stimulation parameters, and then automatically adjusting at least a second of the stimulation parameters in response to adjusting the at least the first of the stimulation parameters, wherein the at least the second of the stimulation parameters is automatically adjusted to maintain the total charge transfer by maintaining the area under the current-time curve over the time period.

13. The method of claim 12, wherein adjusting the at least the first one of the stimulation parameters includes adjusting an amplitude.

14. The method of claim 13, wherein delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width, and automatically adjusting the at least the second of the stimulation parameters includes automatically adjusting the pulse width.

15. The method of claim 12, wherein delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width, and adjusting the at least the first one of the stimulation parameters includes adjusting the pulse width.

16. The method of claim 15, wherein automatically adjusting the at least the second of the stimulation parameters includes automatically adjusting an amplitude of the pulses.

17. The method of claim 12, wherein:

delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

adjusting the at least the first one of the stimulation parameters includes adjusting a pulse frequency of the pulsed electrical current; and

automatically adjusting the at least the second of the stimulation parameters includes automatically adjusting the amplitude, or automatically adjusting the pulse width, or automatically adjusting both the amplitude and the pulse width.

18. The method of claim 12, wherein delivering electrical current includes delivering pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

adjusting the at least the first one of the stimulation parameters includes adjusting the amplitude; and

automatically adjusting the at least the second of the stimulation parameters includes automatically adjusting the pulse frequency.

19. The method of claim 12, wherein the delivered electrical current includes delivering pulsed electrical current that has pulses that have a pulse width and that has a pulse frequency and an amplitude;

adjusting the at least the first one of the stimulation parameters includes adjusting the pulse width; and

automatically adjusting the at least the second of the stimulation parameters includes automatically adjusting the pulse frequency.

20. The method of claim 12, wherein the at least the first of the stimulation parameters or the at least the second of the stimulation parameters includes a pulse rise time, or a pulse fall time, or both the pulse rise time and the pulse fall time.