Method and system for providing data communication in continuous glucose monitoring and management system

• US 9,949,639 B2
• Filed: 06/27/2017
• Issued: 04/24/2018
• Est. Priority Date: 04/29/2009
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Sicurello, Jeffery Mario, Dinh, Hung, Sloan, Mark Kent
• Primary Examiner(s): NWUGO, OJIAKO K
• Application Number:
  US15/634,909
• Publication Number:
  US 20170290511A1
• Time in Patent Office: 301 Days
• Field of Search: 3408707, 600365
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: G06F 15/00 Digital computers in general details G06F1/00 – G06F13/00; Data processing equipment in general
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: H04L 65/00 Network arrangements, protocols or services for supporting real-time applications in data packet communication real-time or near real-time messaging, e.g. instant messaging [IM] H04L51/04; selective video distribution H04N21/00
• CPC Class Codes: H04L 69/324 in the data link layer [OSI layer 2], e.g. HDLC
• CPC Class Codes: H04Q 2209/40 using a wireless architecture
• CPC Class Codes: H04Q 2209/823 where the data is sent when the measured values exceed a threshold, e.g. sending an alarm
• CPC Class Codes: H04Q 2209/86 Performing a diagnostic of the sensing device
• CPC Class Codes: H04Q 9/00 Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom

Abstract

Method and apparatus for providing a data stream generator that generates a data stream associated with a monitored analyte level, and a radio frequency logic portion operatively coupled to the data stream generator, the radio frequency logic portion configured to generate a radio frequency data stream based on the data stream generated from the data stream generator, the radio frequency logic portion further including one or more finite state machines and a plurality of discrete digital logic circuits, the one or more finite state machines configured to control the plurality of digital logic circuits to generate the radio frequency data stream for wireless communication are provided. Systems and kits incorporating the same are also provided.

Claims

1. A glucose monitoring device, comprising:

an in vivo glucose sensor; and

sensor electronics coupleable to the in vivo glucose sensor to receive signals generated by the in vivo glucose sensor, the sensor electronics including;

a data communication unit;

a transmit component to issue a build packet command and a send packet command; and

a data stream generator to build a data packet based on the signals generated by the in vivo sensor in response to the build packet command, and to send the built data packet to the data communication unit in response to the send packet command, the data stream generator further including a serializer component to transition between a first state and a second state, and to serially output data with the transition.

2. The device of claim 1, wherein the transmit component is a transmit state machine, and the data stream generator includes a finite state machine to build the data packet.

3. The device of claim 1, wherein the data stream generator is configured to send a data sent signal to the transmit component indicating that the data packet was transmitted via the data communication unit.

4. The device of claim 1, wherein the data stream generator is the only component of the sensor electronics to store packet data.

5. The device of claim 1, wherein one or more components of the data stream generator are idle when not building data packets.

6. The device of claim 1, wherein the data stream generator includes a multiplexer configured to operate in a first clock domain, and a RF data register configured to operate in a second clock domain, and wherein the transmit component is configured to operate in the first clock domain.

7. The device of claim 1, wherein the data communication unit is a radio frequency (RF) communication unit configured to generate a radio frequency data stream for wireless communication to a receiving device over a RF communication link.

8. The device of claim 7, wherein the data communication unit is configured to generate the radio frequency data stream after the data packets are built.

9. The device of claim 1, wherein the in vivo glucose sensor includes a plurality of electrodes including a working electrode comprising an analyte-responsive enzyme bonded to a polymer disposed on the working electrode.

10. The device of claim 9, wherein the analyte-responsive enzyme is chemically bonded to the polymer disposed on the working electrode.

11. The device of claim 9, wherein the working electrode comprises a mediator bonded to the polymer disposed on the working electrode.

12. The device of claim 11, wherein the mediator is crosslinked with the polymer disposed on the working electrode.

13. A method, comprising:

operating an in vivo glucose sensor and a sensor electronics coupled to the in vivo glucose sensor to receive signals generated by the in vivo glucose sensor, the sensor electronics including a transmit component, a data stream generator, and a serializer component;

generating, using the transmit component of the sensor electronics, a build packet command and a send packet command;

building a data packet, using the data stream generator of the sensor electronics, based on the signals generated by the in vivo sensor in response to the build packet command;

sending, using the data stream generator, the built packet to a data communication unit of the sensor electronics in response to the send packet command;

transitioning, using the serializer component of the data stream generator, between a first state and a second state; and

serially outputting data, using the serializer component, with the transition between the first state and the second state.

14. The method of claim 13, wherein the transmit component is a transmit state machine, the data stream generator includes a finite state machine, and further comprising building the data packet with the finite state machine.

15. The method of claim 13, wherein the data stream generator includes a multiplexer and a RF data register, and further comprising operating the multiplexer and the transmit component in a first clock domain and the RF data register in a second clock domain.

16. The method of claim 13, wherein the data communication unit is a radio frequency (RF) communication unit, and further comprising generating a radio frequency data stream using the RF communication unit;

and wirelessly communicating the radio frequency data stream to a receiving device over a RF communication link after the data packets are built.

17. The method of claim 13, wherein the in vivo glucose sensor includes a plurality of electrodes including a working electrode comprising an analyte-responsive enzyme bonded to a polymer disposed on the working electrode.

18. The method of claim 17, wherein the analyte-responsive enzyme is chemically bonded to the polymer disposed on the working electrode.

19. The method of claim 17, wherein the working electrode comprises a mediator bonded to the polymer disposed on the working electrode.

20. The method of claim 19, wherein the mediator is crosslinked with the polymer disposed on the working electrode.