Noninvasive blood measurement platform
First Claim
1. An apparatus for noninvasive measurement of blood constituents, the apparatus comprising:
- a broad-spectrum light source configured to emit first light having a broad spectrum at a subject;
a broad-spectrum light detector configured to acquire absorption measurements, comprising;
a first measurement of a bulk absorption by the subject of the first light emitted by the broad-spectrum light source at a maximum blood volume, anda second measurement of a bulk absorption by the subject of the first light emitted by the broad-spectrum light source at a minimum blood volume;
a narrow-spectrum light source configured to emit a second light having a narrow spectrum at the subject;
a narrow-spectrum light detector configured to acquire absorption measurements, comprising;
a third measurement of a bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the maximum blood volume, anda fourth measurement of a bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the minimum blood volume;
a processor configured to;
receive the first measurement and the second measurement from the broad-spectrum light detector,receiving the third measurement and the fourth measurement from the narrow-spectrum light detector,determine a first value representing an orthogonality between the first measurement of the bulk absorption by the subject of the first light emitted by the broad-spectrum light source at the maximum blood volume and the third measurement of the bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the maximum blood volume,determine a second value representing an orthogonality between the second measurement of the bulk absorption by the subject of the first light emitted by the broad-spectrum light source at the minimum blood volume and the fourth measurement of the bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the minimum blood volume,determine an amount of at least one blood constituent using the first value and the second value.
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Accused Products
Abstract
A noninvasive blood measurement platform may be used to determine the amounts of various constituents of the blood based on the bulk absorption characteristics of the blood. The platform may measure bulk absorption of energy such as, a broad-spectrum light, to determine maximum and minimum blood volumes. The platform may measure bulk absorption of energy at the maximum and minimum blood volumes. The bulk absorption measurements may be transformed using a transformation operation to determine bulk absorption characteristics in terms of frequency and/or wavelength. A time-varying component of the bulk absorption characteristics may be derived by comparing the bulk absorption characteristics at the maximum blood volume to the bulk absorption characteristics at the minimum blood volume. Multivariate analysis may be performed on the time-varying component to determine the amount of the one or more constituents of the blood.
20 Citations
7 Claims
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1. An apparatus for noninvasive measurement of blood constituents, the apparatus comprising:
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a broad-spectrum light source configured to emit first light having a broad spectrum at a subject; a broad-spectrum light detector configured to acquire absorption measurements, comprising; a first measurement of a bulk absorption by the subject of the first light emitted by the broad-spectrum light source at a maximum blood volume, and a second measurement of a bulk absorption by the subject of the first light emitted by the broad-spectrum light source at a minimum blood volume; a narrow-spectrum light source configured to emit a second light having a narrow spectrum at the subject; a narrow-spectrum light detector configured to acquire absorption measurements, comprising; a third measurement of a bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the maximum blood volume, and a fourth measurement of a bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the minimum blood volume; a processor configured to; receive the first measurement and the second measurement from the broad-spectrum light detector, receiving the third measurement and the fourth measurement from the narrow-spectrum light detector, determine a first value representing an orthogonality between the first measurement of the bulk absorption by the subject of the first light emitted by the broad-spectrum light source at the maximum blood volume and the third measurement of the bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the maximum blood volume, determine a second value representing an orthogonality between the second measurement of the bulk absorption by the subject of the first light emitted by the broad-spectrum light source at the minimum blood volume and the fourth measurement of the bulk absorption by the subject of the second light emitted by the narrow-spectrum light source at the minimum blood volume, determine an amount of at least one blood constituent using the first value and the second value. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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Specification