Replacement heart valves, delivery devices and methods
First Claim
1. A method of delivering a replacement valve to a native mitral valve and securing the replacement valve relative to the native mitral valve annulus, the native mitral valve annulus supporting native leaflets, the method comprising:
- delivering a replacement valve mounted on a delivery device to the native mitral valve annulus while the replacement valve is in a radially compacted state, the replacement valve comprising;
a radially expandable frame;
a first plurality of anchors extending from the frame; and
a valve body positioned within the frame, the valve body having an inflow end and an outflow end; and
positioning the replacement valve so that tips of the first plurality of anchors are on a ventricular side of the native leaflets beyond a location where chordae tendineae connect to free ends of the native leaflets;
releasing at least a portion of the replacement valve from the delivery device to thereby expand the first plurality of anchors radially outwardly; and
engaging the tips of the first plurality of anchors with tissue on the ventricular side of the native mitral valve annulus with the first plurality of anchors extending between at least some of the chordae tendineae;
wherein, after engaging the tips, the replacement valve is positioned so that;
a portion of the frame, having a larger diameter than an inflow end of the replacement valve, is positioned within the native mitral valve annulus;
an outflow portion of the replacement valve extends distally and bends radially inwardly towards a longitudinal axis of the replacement valve at or proximate an outflow end; and
the portion of the frame within the native mitral valve annulus has a larger cross-sectional dimension than a periphery of the frame adjacent the inflow end of the valve body;
with the tips of the plurality of first anchors engaging tissue on the ventricular side of the native mitral valve annulus, further releasing the replacement valve from the delivery device and expanding the frame to a radially expanded state, wherein further releasing the replacement valve causes a second plurality of anchors extending from the frame to engage tissue on an atrial side of the native mitral valve annulus.
3 Assignments
0 Petitions
Accused Products
Abstract
A replacement heart valve and method of treating valve insufficiency includes an expandable frame configured to engage a native valve annulus. A valve body is coupled to the frame. The valve body can include a leaflet portion and possibly a skirt portion. A portion of the frame has a foreshortening portion configured to longitudinally expand when urged to a radially compacted state and longitudinally contract when urged to a radially expanded state. In one embodiment the valve skirt is attached to the frame so that it can adapt to changes in the length of the frame. A delivery device in some embodiments can use one or more coverings, such as sheaths, to controllably release the replacement heart valve at a native heart valve.
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Citations
17 Claims
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1. A method of delivering a replacement valve to a native mitral valve and securing the replacement valve relative to the native mitral valve annulus, the native mitral valve annulus supporting native leaflets, the method comprising:
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delivering a replacement valve mounted on a delivery device to the native mitral valve annulus while the replacement valve is in a radially compacted state, the replacement valve comprising; a radially expandable frame; a first plurality of anchors extending from the frame; and a valve body positioned within the frame, the valve body having an inflow end and an outflow end; and positioning the replacement valve so that tips of the first plurality of anchors are on a ventricular side of the native leaflets beyond a location where chordae tendineae connect to free ends of the native leaflets; releasing at least a portion of the replacement valve from the delivery device to thereby expand the first plurality of anchors radially outwardly; and engaging the tips of the first plurality of anchors with tissue on the ventricular side of the native mitral valve annulus with the first plurality of anchors extending between at least some of the chordae tendineae; wherein, after engaging the tips, the replacement valve is positioned so that; a portion of the frame, having a larger diameter than an inflow end of the replacement valve, is positioned within the native mitral valve annulus; an outflow portion of the replacement valve extends distally and bends radially inwardly towards a longitudinal axis of the replacement valve at or proximate an outflow end; and the portion of the frame within the native mitral valve annulus has a larger cross-sectional dimension than a periphery of the frame adjacent the inflow end of the valve body; with the tips of the plurality of first anchors engaging tissue on the ventricular side of the native mitral valve annulus, further releasing the replacement valve from the delivery device and expanding the frame to a radially expanded state, wherein further releasing the replacement valve causes a second plurality of anchors extending from the frame to engage tissue on an atrial side of the native mitral valve annulus. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of delivering a replacement valve to a native mitral valve and securing the replacement valve relative to the native mitral valve annulus, the native mitral valve annulus supporting native leaflets, the method comprising:
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delivering a replacement valve mounted on a delivery device to the native mitral valve annulus while the replacement valve is in a radially compacted state, the replacement valve comprising a radially expandable frame and a first plurality of anchors extending from the frame; and positioning the replacement valve so that tips of the first plurality of anchors are on a ventricular side of the native leaflets beyond a location where chordae tendineae connect to free ends of the native leaflets; releasing at least a portion of the replacement valve from the delivery device to thereby expand the first plurality of anchors radially outwardly; and engaging the tips of the first plurality of anchors with tissue on the ventricular side of the native mitral valve annulus with the first plurality of anchors extending between at least some of the chordae tendineae, wherein, after engaging the tips, the replacement valve is positioned so that an outflow end of the replacement valve has a larger diameter than an inflow end of the replacement valve; with the tips of the plurality of first anchors engaging tissue on the ventricular side of the native mitral valve annulus, further releasing the replacement valve from the delivery device and expanding the frame to a radially expanded state, wherein further releasing the replacement valve causes a second plurality of anchors extending from the frame to engage tissue on an atrial side of the native mitral valve annulus; wherein the tips of the first plurality of anchors and tips of the second plurality of anchors are located downstream of replacement valve leaflets located in the inflow end of the replacement heart valve. - View Dependent Claims (11, 12)
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13. A method of delivering a replacement valve to a native mitral valve and securing the replacement valve relative to the native mitral valve annulus, the native mitral valve annulus supporting native leaflets, the method comprising:
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delivering a replacement valve mounted on a delivery device to the native mitral valve annulus while the replacement valve is in a radially compacted state, the replacement valve comprising a radially expandable frame and a first plurality of anchors extending from the frame; and releasing the first plurality of anchors and at least a downstream portion of the frame from the delivery device such that the first plurality of anchors expand radially outwardly and the downstream portion expands to at least a substantially full extent; and after the first plurality of anchors expand radially outwardly and the downstream portion expands to at least the substantially full extent, engaging tips of the first plurality of anchors with tissue on a ventricular side of the native mitral valve annulus with the first plurality of anchors extending between at least some of the chordae tendineae; wherein, after engaging the tips, the replacement valve is positioned so that a portion of the frame, having a larger diameter than an inflow end of the replacement valve, is positioned within the native mitral valve annulus. - View Dependent Claims (14, 15, 16, 17)
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Specification