Drug component admixture library for a drug infusion delivery system

• US 9,953,138 B2
• Filed: 06/29/2010
• Issued: 04/24/2018
• Est. Priority Date: 06/29/2010
• Status: Active Grant

• Current Assignee: Medos International Sarl (Johnson & Johnson)
• Original Assignee: Codman Neuro Sciences Sarl
• Inventors: Chossat, Olivier, Flynn, Timothy
• Primary Examiner(s): Seoh, Minnah L
• Application Number:
  US12/803,574
• Publication Number:
  US 20110320049A1
• Time in Patent Office: 2,856 Days
• Field of Search: 705 2- 3
• CPC Class Codes: A61M 5/1407 Infusion of two or more substances
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 70/40 relating to drugs, e.g. their side effects or intended usage

Abstract

Minimizing improper dosage of a drug admixture (including a single primary drug component and at least one second drug component). For each drug component in the drug admixture, receiving a name of the drug component along with its dosage unit, a maximum dose warning level and a maximum concentration warning level. Receiving a concentration for each of the single primary drug component and the at least one secondary drug component; and a dose setting of only the primary drug component. Automatically calculating a dose of each of the at least one secondary drug component. Generating an alert when: (i) the received dose setting of the primary drug component or calculated dose setting of the at least one secondary drug component exceeds the dose warning level; or (ii) the received concentration of the primary drug component or the at least one secondary drug component exceeds the concentration warning level.

Claims

1. A method for minimizing improper dosage of a drug admixture dispensed from a reservoir of a drug infusion delivery system, the drug admixture including a single primary drug component and at least one secondary drug component, comprising the steps of:

for each drug component in the drug admixture, receiving as user input from a surface of a data entry device drug component admixture library data including a name of the drug component along with its dosage unit, a maximum dose warning level and a maximum concentration warning level;

storing in a first memory device the received drug component admixture library data for each drug component in the drug admixture;

receiving as additional user input (i) a concentration for each of the single primary drug component and the at least one secondary drug component; and

(ii) a dose setting of only the primary drug component;

automatically determining using a processor, a calculated dose of each of the at least one secondary drug component based on the received dose setting for only the primary drug component and the concentration for that secondary drug component;

generating an alert when;

(i) the received dose setting of the primary drug component or calculated dose setting of the at least one secondary drug component exceeds the dose warning level for that drug component stored in the first memory device;

or (ii) the received concentration of the primary drug component or the at least one secondary drug component exceeds the concentration warning level for that drug component stored in the first memory device;

if no alert is generated, dispensing the drug admixture from the reservoir of the drug infusion delivery system.

2. The method in accordance with claim 1, wherein the received dose setting for only the primary drug component is a new dose setting or a modified dose setting from that of a previous dose setting for only the primary drug component.

3. The method in accordance with claim 2, wherein the received dose setting for only the primary drug component is the modified dose setting of the primary drug component expressed as a percentage increase/decrease based on the previous dose setting.

4. The method in accordance with claim 3, further comprising the step of displaying the percentage increase/decrease in the dose setting of the primary drug component.

5. The method in accordance with claim 1, wherein the automatic determining step further comprises the step of automatically updating a daily dose of the primary drug component based on a received hourly dose and/or time period block dose of the primary drug component.

6. The method in accordance with claim 5, wherein the automatic determining step further comprises the step of automatically updating hourly and/or daily doses for each of the at least one secondary drug components based on the received concentration of that secondary drug component.

7. The method in accordance with claim 1, wherein the drug infusion delivery system includes an implantable drug infusion delivery device and the external control device, the processor and the first memory device are associated with the external control device, a second memory device associated with the implantable drug infusion delivery device stores patient prescription data including:

(i) the received concentration for each of the primary drug component and the at least one secondary drug component;

(ii) the received dose setting of only the primary drug component; and

(iii) the calculated dose of each of the at least one secondary drug component.

8. The method in accordance with claim 7, further comprising the step of transmitting new and/or updated patient prescription data from the control device to the implantable drug infusion delivery device.

9. A non-transitory computer readable medium having a computer readable program code embodied therein, the computer readable program code adapted to be executed to implement a method for minimizing improper dosage of a drug admixture to be dispensed from a reservoir of a drug infusion delivery system, the drug admixture including a single primary drug component and at least one secondary drug component, the method comprising the steps of:

providing the drug infusion delivery system, wherein the drug infusion delivery system comprises distinct software modules, and wherein the distinct software modules comprise a drug component admixture library data receiving module, a logic processing module, a drug component admixture library module and a patient prescription data transmitting/receiving module;

for each drug component in the drug admixture, receiving as user input from a surface of a data entry device drug component admixture library data via the drug component admixture library data receiving module, wherein the drug component admixture library data includes a name for that drug component along with its dosage unit, a maximum concentration warning level and a maximum dose warning level;

storing in a first memory device as a drug component admixture library the received drug component admixture library data, the drug component admixture library being stored in memory using the drug component admixture library module;

receiving as additional user input using a patient prescription data transmitting/receiving module;

(i) a concentration for each of the single primary drug component and the at least one secondary drug component; and

(ii) a dose setting of only the primary drug component;

automatically determining using the logic processing module, a calculated dose of each of the at least one secondary drug component based on the received dose setting for only the primary drug component and the received concentration for that secondary drug component; and

generating an alert when;

(i) the received dose setting of the primary drug component or calculated dose setting of the at least one secondary drug component exceeds the dose warning level for that drug component stored in the first memory device;

or (ii) the received concentration of the primary drug component or the at least one secondary drug component exceeds the concentration warning level for that drug component stored in the first memory device;

if no alert is generated, dispensing the drug admixture from the reservoir of the drug infusion delivery system.

10. The non-transitory computer readable medium in accordance with claim 9, wherein the dose setting for only the received primary drug component is a new dose setting or a modified dose to a previous dose setting for only the primary drug component.

11. The non-transitory computer readable medium in accordance with claim 10, wherein the received dose setting for only the primary drug component received is the modified dose of a previous dose setting of the primary drug component expressed as a percentage increase/decrease based on the previous dose setting.

12. The non-transitory computer readable medium in accordance with claim 11, wherein the drug infusion delivery system includes a data display module, further comprising the step of displaying using the data display module the percentage increase/decrease in the dose setting of the primary drug component.

13. The non-transitory computer readable medium in accordance with claim 9, wherein the automatic determining step further comprises the step of automatically updating a daily dose of the primary drug component based on a received hourly dose and/or time period block dose of the primary drug component.

14. The non-transitory computer readable medium in accordance with claim 13, wherein the automatic determining step further comprises the step of automatically updating hourly and/or daily doses for each of the at least one secondary drug components based on the received concentration of that secondary drug component.

15. The non-transitory computer readable medium in accordance with claim 9, wherein the drug infusion delivery system includes an implantable drug infusion delivery device and an external control device, the distinct software modules and the first memory device being associated with the external control device;

a second memory device associated with the implantable drug infusion delivery device stores patient prescription data including;

(i) the received concentration for each of the primary drug component and the at least one secondary drug component;

(ii) the received dose setting of only the primary drug component; and

(iii) the calculated dose of each of the at least one secondary drug component.

16. The non-transitory computer readable medium in accordance with claim 9, further comprising the step of transmitting new and/or updated patient prescription data received by the control device to the implantable drug infusion delivery device via the patient prescription data transmitting/receiving module to be stored in a second memory device associated with the implantable drug infusion delivery device.

17. A drug infusion delivery system for minimizing improper dosage of a drug admixture to be dispensed from a reservoir of a drug infusion delivery system, the drug admixture including a single primary drug component and at least one secondary drug component, the system comprising:

a control device comprising;

a data entry device for providing;

(i) for each drug component in the drug admixture, drug component admixture library data received as user input from a surface of a data entry device including;

a name for that drug component along with its dosage unit, a maximum concentration warning level and a maximum dose warning level;

(ii) a concentration for each drug component in the drug admixture and (ii) a dose setting for only the primary drug component;

a first memory device for storing for each drug component in the drug admixture the drug component admixture library data; and

a processor for automatically determining a calculated dose of each of the at least one secondary drug component based on the received dose setting for only the primary drug component and the concentration for that secondary drug component stored in the first memory device; and

circuitry for generating an alert initiated by the processor when;

(i) the received dose setting of the primary drug component or the calculated dose of each of the at least one secondary drug component exceeds the dose warning level for that drug component stored in the first memory device;

or (ii) the concentration of the primary drug component or the at least one secondary drug component exceeds the concentration warning level for that drug component stored in the first memory device;

if no alert is generated, the circuitry dispensing the drug admixture from the reservoir of the drug infusion delivery system.

18. The drug infusion delivery system in accordance with claim 17, wherein the dose setting for only the primary drug component is a new dose setting or a modified dose to a previous dose setting for only the single primary drug component.

19. The drug infusion delivery system in accordance with claim 18, wherein the dose setting for only the primary drug component is the modified dose of the previous dose setting of the primary drug component expressed as a percentage increase/decrease based on the previous dose setting.

20. The drug infusion delivery system in accordance with claim 19, wherein the control device further comprises a display for displaying the percentage increase/decrease in the dose setting of the primary drug component.

21. The drug infusion delivery system in accordance with claim 17, wherein the processor performs the further function of automatically updating a daily dose of the primary drug component based on a specified hourly dose and/or time period block dose of the primary drug component.

22. The drug infusion delivery system in accordance with claim 21, wherein the automatic determining function performed by the processor further comprises the step of automatically updating hourly and/or daily doses for each of the at least one secondary drug components based on the concentration of that secondary drug component stored in a second memory.

23. The drug infusion delivery system in accordance with claim 17, further comprising an implantable drug infusion delivery device;

new and/or updated concentration and dose data being transmitted from the control device to the implantable drug infusion delivery device and stored in a second memory device associated with the implantable drug infusion delivery device.