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Functional near-infrared spectroscopy as a monitor for depth of anesthesia

  • US 9,955,901 B2
  • Filed: 06/17/2014
  • Issued: 05/01/2018
  • Est. Priority Date: 09/30/2008
  • Status: Active Grant
First Claim
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1. A method of removing the effect of an artifact on a functional near-infrared signal of a cortical anesthesia monitoring system to improve the system accuracy, the method comprising:

  • capturing a functional near-infrared signal of a patient, the functional near-infrared signal including a non-cortical signal, wherein the non-cortical signal is indicative of a signal-causing artifact;

    processing the functional near-infrared signal with a principal component analysis (PCA) noise removal algorithm and an independent component analysis (ICA) noise removal algorithm,analyzing outputs from the principal component analysis and the independent component analysis algorithms to select an artifact signal; and

    removing the effect of the artifact from the functional near-infrared signal by subtracting a portion of the non-cortical signal from the functional near-infrared signal based on the selected artifact signal.

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