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Compositions and methods for modulating angiopoietin-like 3 expression

  • US 9,957,292 B2
  • Filed: 12/04/2015
  • Issued: 05/01/2018
  • Est. Priority Date: 05/01/2014
  • Status: Active Grant
First Claim
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1. A compound comprising a modified oligonucleotide and a conjugate group, wherein the modified oligonucleotide consists of 12 to 30 linked nucleosides having a nucleobase sequence comprising at least 12 contiguous nucleobases complementary to an equal length portion of any of SEQ ID NOs:

  • 1-2, and wherein the conjugate group comprises;

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