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Compounds for inducing anti-tumor immunity and methods thereof

  • US 9,957,506 B2
  • Filed: 09/25/2014
  • Issued: 05/01/2018
  • Est. Priority Date: 09/25/2013
  • Status: Active Grant
First Claim
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1. A method for enhancing or inducing an anti-tumor immune response in a subject, comprising administering to the subject an effective amount of a direct inhibitor of IRE1α

  • for enhancing or inducing an anti-tumor immune response in the subject, wherein the effective amount of the direct inhibitor IRE1α

    increases antigen presentation in antigen presenting cells, wherein the tumor is a solid tumor, and wherein the solid tumor is from an ovarian cancer, epithelial cancer, germ cell cancer, a stromal tumor.

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