Systems and methods for VOA model generation and use
First Claim
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1. A system for estimating a volume of activation using a set of electrical stimulation settings, the system comprising:
- a processor configured to;
receive electric field data and the set of electrical stimulation settings for use with a non-cylindrically symmetrical implanted leadwire;
apply the electric field data and the set of electrical stimulation settings to a volume of activation estimation model to determine a value for each of one of more locations for each of a plurality of neural elements, wherein the volume of activation estimation model either
1) does not use as input a plurality of sets of values of an electrical field at different points in time,
2) includes only linear equations generated based on observed functioning of a model that uses differential equations, or
3) does not use more than one differential equation;
output an indication of an estimated volume of activation based on the values for each of the one or more locations for each of the neural elements; and
initiate a signal to convey the set of electrical stimulation settings to an implanted pulse generator to transmit signals via a leadwire for stimulation of patient tissue according to the set of electrical stimulation settings.
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Abstract
A computer implemented system and method provides a volume of activation (VOA) estimation model that receives as input two or more electric field values of a same or different data type at respective two or more positions of a neural element and determines based on such input an activation status of the neural element. A computer implemented system and method provides a machine learning system that automatically generates a computationally inexpensive VOA estimation model based on output of a computationally expensive system.
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Citations
20 Claims
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1. A system for estimating a volume of activation using a set of electrical stimulation settings, the system comprising:
a processor configured to; receive electric field data and the set of electrical stimulation settings for use with a non-cylindrically symmetrical implanted leadwire; apply the electric field data and the set of electrical stimulation settings to a volume of activation estimation model to determine a value for each of one of more locations for each of a plurality of neural elements, wherein the volume of activation estimation model either
1) does not use as input a plurality of sets of values of an electrical field at different points in time,
2) includes only linear equations generated based on observed functioning of a model that uses differential equations, or
3) does not use more than one differential equation;output an indication of an estimated volume of activation based on the values for each of the one or more locations for each of the neural elements; and initiate a signal to convey the set of electrical stimulation settings to an implanted pulse generator to transmit signals via a leadwire for stimulation of patient tissue according to the set of electrical stimulation settings. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A non-transitory computer-readable medium having instructions stored thereon and executable by a processor, the instructions comprising:
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receiving electric field data and the set of electrical stimulation settings for use with a non-cylindrically symmetrical implanted leadwire; applying the electric field data and the set of electrical stimulation settings to a volume of activation estimation model to determine a value for each of one of more locations for each of a plurality of neural elements, wherein the volume of activation estimation model either
1) does not use as input a plurality of sets of values of an electrical field at different points in time,
2) includes only linear equations generated based on observed functioning of a model that uses differential equations, or
3) does not use more than one differential equation;outputting an indication of an estimated volume of activation based on the values for each of the one or more locations for each of the neural elements; and initiating a signal to convey the set of electrical stimulation settings to an implanted pulse generator to transmit signals via a leadwire for stimulation of patient tissue according to the set of electrical stimulation settings. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20)
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Specification