Use of antisecretory factors (AF) for optimizing cellular uptake
First Claim
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1. A composition comprising the amino acid sequence consisting of SEQ ID NO:
- 4 or a pharmaceutically acceptable salt thereof in combination with a non-peptidic low molecular weight drug which is cytotoxic or cytostatic.
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Abstract
The present invention relates to the use of an antisecretory factor (AF) protein, peptide, derivative, homologue, and/or fragment thereof, having equivalent functional activity, and/or a pharmaceutically active salt thereof, for optimizing delivery and cellular uptake of a pharmaceutical substance and/or formulation, or a gene delivery. Typically, said pharmaceutical substance and/or formulation comprises an anticancer drug, radiation therapy, an antibiotic substance, an antiviral substance or a drug targeting posttraumatic injury, neurodegeneration, a parasite, or an inflammatory condition.
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Citations
10 Claims
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1. A composition comprising the amino acid sequence consisting of SEQ ID NO:
- 4 or a pharmaceutically acceptable salt thereof in combination with a non-peptidic low molecular weight drug which is cytotoxic or cytostatic.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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