Seeping flow anti-clotting blood catheter

• US 9,962,519 B2
• Filed: 01/13/2015
• Issued: 05/08/2018
• Est. Priority Date: 01/14/2014
• Status: Active Grant

• Current Assignee: Charles Stark Draper Laboratory Incorporated
• Original Assignee: Charles Stark Draper Laboratory Incorporated
• Inventors: Charest, Joseph L., Hsiao, James, DiBiasio, Christopher, Hufford, Kevin A.
• Primary Examiner(s): Price, Nathan R
• Assistant Examiner(s): DOUBRAVA, JOHN A
• Application Number:
  US14/595,938
• Publication Number:
  US 20170100564A1
• Time in Patent Office: 1,211 Days
• Field of Search: 604266
• CPC Class Codes: A61M 2025/0057 Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
• CPC Class Codes: A61M 2025/006 having a special surface topography or special surface properties, e.g. roughened or knurled surface
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 25/0029 characterized by features relating to least one lumen located at the middle part of the catheter, e.g. slots, flaps, valves, cuffs, apertures, notches, grooves or rapid exchange ports catheter shaft surface irregularities A61M2025/006
• CPC Class Codes: A61M 25/0043 characterised by structural features

Abstract

The device and methods described herein relate to a seeping flow catheter. The seeping flow catheter includes a porous material. The inner face of the porous material defines the lumen of the catheter. The porous material is configured such that fluid can flow along the length of the catheter, between the inner face and outer face of the porous material. As the fluid flows through the porous material, the fluid can seep into the lumen of the catheter through the inner face or out of the catheter through the outer face of the porous material. Portions of the inner or outer face can include a lining that substantial reduces the perfusion of the fluid through the lined areas.

Claims

1. A catheter comprising:

an elongated tube having a distal end and a proximal end, the elongated tube comprising a porous material having an interior face and an exterior face, the interior face defining a lumen along a central axis of the elongated tube, the porous material being configured to flow a fluid substantially parallel to the central axis between the interior face and the exterior face of the porous material and to seep the fluid out of the porous material through the exterior face and interior face, a first section including a first outer lining covering the exterior face of the first section and configured to substantially limit perfusion of fluid through the exterior face of the first section, and an unlined section extending from a distal end of the first section, the interior and exterior faces of the unlined section including unlined porous material; and

a fitting coupled to the proximal end of the elongated tube, the fitting configured to flow a first fluid into the porous material and a second fluid into the lumen.

2. The catheter of claim 1, wherein the first fluid is different than the second fluid.

3. The catheter of claim 1, wherein the resistance to flow through the inner face or exterior face of the porous material is between about 10 and about 100 times higher than the resistance to flow through the porous material along an axis parallel to the central axis of the elongated tube.

4. The catheter of claim 1, wherein the thickness of the porous material is between about 20 μ

m and about 1 mm.

5. The catheter of claim 1, wherein the porous material comprises phase inversion polyethersulfone.

6. The catheter of claim 1, where in the interior face has a first porosity at a first distance from the proximal end of the elongated tube and a second porosity at a second distance from the proximal end of the elongated tube.

7. The catheter of claim 1, wherein the elongated tube further comprises:

a second section extending from a distal end of the unlined section and including a second outer lining covering the exterior face of the second section, the second outer lining configured to substantially limit perfusion of fluid through the exterior face of the second section; and

an unlined tip portion extending from a distal end of the second section, the interior and exterior faces of the unlined tip section including unlined porous material.

8. The catheter of claim 7, wherein the second outer lining has a porosity greater than the first outer lining.

9. The catheter of claim 7, wherein the unlined tip portion of the elongated tube includes an open distal end providing for fluid flow out from the lumen of the elongated tube in a direction parallel to the central axis and for fluid to flow out from the porous material in a direction parallel to the central axis.

10. The catheter of claim 7, wherein the interior face of the second section of the elongated tube includes unlined porous material.

11. The catheter of claim 1, further comprising an inner lining covering the interior face of the first section of the elongated tube and configured to substantially limit perfusion of fluid through the interior face of the first section of the elongated tube.

12. The catheter of claim 11, wherein one or more of the first outer lining, the second outer lining, and the inner lining includes an adhesive coating.

13. The catheter of claim 11, wherein one or more of the first outer lining, the second outer lining, and the inner lining includes a surface of the porous material that has been melted to seal the pores of the surface of the porous material.

14. A catheter comprising:

an elongated tube having a distal end and a proximal end, the elongated tube comprising a porous material having an interior face and an exterior face, the interior face defining a lumen along a central axis of the elongated tube, the porous material being configured to flow a fluid substantially parallel to the central axis between the interior face and the exterior face of the porous material and to seep the fluid out of the porous material through the exterior face and interior face; and

a fitting coupled to the proximal end of the elongated tube, the fitting configured to flow a first fluid into the porous material and a second fluid into the lumen, the fitting including a collar disposed about a circumference of the catheter and configured to inject the first fluid into the porous material through the exterior face of the porous material.