Collimator and energy degrader

• US 9,962,560 B2
• Filed: 12/20/2013
• Issued: 05/08/2018
• Est. Priority Date: 12/20/2013
• Status: Active Grant

• Current Assignee: Mevion Medical Systems Incorporated
• Original Assignee: Mevion Medical Systems Incorporated
• Inventors: Zwart, Gerrit Townsend, Jones, Mark R., Cooley, James
• Primary Examiner(s): LOGIE, MICHAEL J
• Application Number:
  US14/137,854
• Publication Number:
  US 20150174429A1
• Time in Patent Office: 1,600 Days
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1095 Elements inserted into the radiation path within the system, e.g. filters or wedges
• CPC Class Codes: A61N 5/1042 with spatial modulation of the radiation beam within the treatment head
• CPC Class Codes: A61N 5/1043 Scanning the radiation beam, e.g. spot scanning or raster scanning
• CPC Class Codes: A61N 5/1045 using a multi-leaf collimator, e.g. for intensity modulated radiation therapy or IMRT
• CPC Class Codes: A61N 5/1048 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: A61N 5/1077 Beam delivery systems
• CPC Class Codes: A61N 5/1081 Rotating beam systems with a specific mechanical construction, e.g. gantries
• CPC Class Codes: A61N 5/1083 Robot arm beam systems
• CPC Class Codes: G21K 1/046 varying the contour of the field, e.g. multileaf collimators
• CPC Class Codes: G21K 1/10 Scattering devices; Absorbing devices; Ionising radiation filters
• CPC Class Codes: H05H 13/02 Synchrocyclotrons, i.e. frequency modulated cyclotrons
• CPC Class Codes: H05H 2007/004 for modifying beam energy, e.g. spread out Bragg peak devices
• CPC Class Codes: H05H 2007/007 for focusing the beam to irradiation target
• CPC Class Codes: H05H 2007/122 by electromagnetic means, e.g. RF cavities

Abstract

A particle therapy system includes a particle accelerator to output a particle beam; and a scanning system for the particle accelerator to scan the particle beam across at least part of an irradiation target. The scanning system is configured to scan the particle beam in two dimensions that are at an angle relative to a direction of the particle beam. A structure defines an edge. The structure is controllable to move in the two dimensions relative to the irradiation target such that at least part of the structure is between at least part of the particle beam and the irradiation target. The structure includes a material that inhibits transmission of the particle beam.

Claims

1. A particle therapy system comprising:

a particle accelerator to output a particle beam;

a scanning system for the particle accelerator to scan the particle beam across at least part of an irradiation target in a patient, the scanning system being configured to scan the particle beam in at least two dimensions across the at least part of the irradiation target; and

a collimator comprising multiple elements that are controllable to move in the at least two dimensions relative to the particle beam during scanning to track motion of the particle beam as the particle beam is scanned across the at least part of the irradiation target, the multiple elements comprising a material that inhibits transmission of the particle beam, each of the multiple elements comprising fingers that are extendible and retractable in one of the two dimensions to define an edge of the collimator that is movable between a first part of the particle beam and the patient to prevent the first part of the particle beam from reaching the patient while allowing a second part of the particle beam to reach the at least part of the irradiation target.

2. The particle therapy system of claim 1, wherein each of the multiple elements is rotatable.

3. The particle therapy system of claim 1, wherein the fingers are adjustable to vary a size of the edge.

4. The particle therapy system of claim 1, wherein the fingers are individually movable relative to the irradiation target.

5. The particle therapy system of claim 1, wherein the multiple elements comprise a first element and a second element, the first element for defining the edge, the edge being a first edge, and the second element for defining a second edge;

and

wherein the first edge and the second edge are controllable to move relative to the irradiation target.

6. The particle therapy system of claim 1, wherein the scanning system comprises at least one magnet to control movement of the particle beam to scan the particle beam, the at least one magnet for generating a magnetic field in response to applied current, the magnetic field affecting the movement.

7. The particle therapy system of claim 1, wherein the scanning system is configured to scan the particle beam more quickly in interior sections of the irradiation target than at a perimeter of the irradiation target.

8. The particle therapy system of claim 1, wherein the particle beam is movable within an area of a plane;

and

wherein the scanning system comprises an energy degrader having an area that is less than the area of the plane.

9. The particle therapy system of claim 8, wherein the energy degrader has an area that is less than half the area of the plane.

10. The particle therapy system of claim 8, wherein the energy degrader has an area that is less than a quarter the area of the plane.

11. The particle therapy system of claim 8, wherein the energy degrader has an area that is less than an eighth the area of the plane.

12. The particle therapy system of claim 8, wherein the energy degrader has an area that is less than ten times a cross-sectional area of the particle beam.

13. The particle therapy system of claim 1, wherein the scanning system is configured to scan the particle beam from different incident angles;

and

wherein the multiple elements are controllable to move based on movement of the particle beam as the particle beam is scanned from different incident angles.

14. The particle therapy system of claim 1, wherein the scanning system comprises:

a magnet to affect a direction of the particle beam to scan the particle beam across the at least part of an irradiation target; and

a degrader to change an energy of the beam prior to application of the particle beam to the irradiation target, the degrader being down-beam of the magnet relative to the particle accelerator;

wherein the particle accelerator is a variable-energy synchrocyclotron.

15. The particle therapy system of claim 1, wherein the particle accelerator is a synchrocyclotron.

16. A particle therapy system comprising:

a particle accelerator to output a particle beam to treat an irradiation target in a patient;

a scanning system for the particle accelerator to scan the particle beam across at least part of the irradiation target, the scanning system being configured to scan the particle beam in at least two dimensions that are at an angle relative to a direction of the particle beam; and

a collimator comprising multiple elements that are controllable to move in the at least two dimensions relative to the particle beam to track movement of the particle beam as the particle beam is scanned across the at least part of the irradiation target, the multiple elements comprising a material that inhibits transmission of the particle beam, and each of the multiple elements comprising fingers that are extendible and retractable in one of the two dimensions to define an edge of the collimator that is movable between a first part of the particle beam and the patient to prevent the first part of the particle beam from reaching the patient while allowing a second part of the particle beam to reach the at least part of the irradiation target;

wherein the particle accelerator comprises;

a voltage source to provide a radio frequency (RF) voltage to a cavity to accelerate particles from a plasma column, the cavity having a magnetic field causing particles accelerated from the plasma column to move orbitally within the cavity;

an extraction channel to receive the particles accelerated from the plasma column and to output the received particles from the cavity; and

a regenerator to provide a magnetic field bump within the cavity to thereby change successive orbits of the particles accelerated from the plasma column so that, eventually, particles output to the extraction channel;

wherein the magnetic field is between 4 Tesla (T) and 20 T and the magnetic field bump is at most 2 Tesla.

17. The particle therapy system of claim 16, wherein the multiple elements are rotatable.

18. The particle therapy system of claim 16, wherein the fingers are adjustable to vary a size of the edge.

19. The particle therapy system of claim 16, wherein the fingers are individually movable relative to the irradiation target.

20. The particle therapy system of claim 16, wherein the multiple elements comprise a first element and a second element, the first element for defining the edge, the edge being a first edge, and the second element for defining a second edge;

and

wherein the first edge and the second edge are controllable to move relative to the irradiation target.

21. The particle therapy system of claim 16, wherein the scanning system comprises at least one magnet to control movement of the particle beam to scan the particle beam, the at least one magnet for generating a magnetic field in response to applied current, the magnetic field affecting the movement.

22. The particle therapy system of claim 16, wherein the scanning system is configured to scan the particle beam more quickly in interior sections of the irradiation target than at a perimeter of the irradiation target.

23. The particle therapy system of claim 16, wherein the particle beam is movable within an area of a plane;

and

wherein the scanning system comprises an energy degrader having an area that is less than the area of the plane.

24. The particle therapy system of claim 23, wherein the energy degrader has an area that is less than half the area of the plane.

25. The particle therapy system of claim 23, wherein the energy degrader has an area that is less than a quarter the area of the plane.

26. The particle therapy system of claim 23, wherein the energy degrader has an area that is less than an eighth the area of the plane.

27. The particle therapy system of claim 23, wherein the energy degrader has an area that is less than ten times a cross-sectional area of the particle beam.

28. The particle therapy system of claim 16, wherein the scanning system is configured to scan the particle beam from different incident angles;

and

wherein the multiple elements are controllable to move based on movement of the particle beam as the particle beam is scanned from different incident angles.

29. The particle therapy system of claim 16, wherein the scanning system comprises:

a magnet to affect a direction of the particle beam to scan the particle beam across the at least part of an irradiation target; and

a degrader to change an energy of the particle beam prior to application of the particle beam to the irradiation target, the degrader being down-beam of the magnet relative to the particle accelerator;

wherein the particle accelerator is a variable-energy synchrocyclotron.

30. The particle therapy system of claim 16, wherein the particle accelerator is a synchrocyclotron.

31. A particle therapy system comprising:

a particle accelerator to output a particle beam to treat an irradiation target in a patient;

a scanning system to perform scanning of at least part of the irradiation target with the particle beam;

a collimator comprised of multiple elements that are controllable to move in at least two dimensions relative to the particle beam during scanning to track motion of the particle beam as the particle beam is scanned across the at least part of the irradiation target, the multiple elements comprising a material that inhibits transmission of the particle beam, and each of the multiple elements comprising fingers that are extendible and retractable in one of the two dimensions to define an edge of the collimator that is movable between a first part of the particle beam and the patient to prevent the first part of the particle beam from reaching the patient while allowing a second part of the particle beam to reach the at least part of irradiation target; and

a gantry on which the particle accelerator is mounted, the gantry being configured to move the particle accelerator relative to the irradiation target.

32. The particle therapy system of claim 31, wherein the multiple elements comprise a first element and a second element, the first element for defining the edge, the edge being a first edge, and the second element for defining a second edge;

and

wherein the first edge and the second edge are controllable to move relative to the irradiation target.

33. The particle therapy system of claim 31, wherein the multiple elements are rotatable.

34. The particle therapy system of claim 31, wherein the scanning system is configured to scan the particle beam more quickly in interior sections of the irradiation target than at a perimeter of the irradiation target.

35. The particle therapy system of claim 31, wherein the scanning system is configured to scan the particle beam from different incident angles;

and

wherein the multiple elements are controllable to move based on movement of the particle beam as the particle beam is scanned from different incident angles.

36. The particle therapy system of claim 31, wherein the particle accelerator is a synchrocyclotron.

37. A particle therapy system comprising:

a particle accelerator to output a particle beam;

a scanning system for the particle accelerator, the scanning system being configured to move the particle beam across an irradiation field, the irradiation field comprising a maximum extent that the particle beam is movable in at least two dimensions; and

a collimator that is down-beam of the scanning system, the collimator comprising multiple elements, at least one of the multiple elements comprising fingers that are extendible and retractable to define an edge of the collimator to block at least part of the particle beam, the multiple elements being controllable to move in the two dimensions relative to the particle beam within the irradiation field to track movement of the particle beam, the fingers of the at least one of the multiple elements being configurable during movement of the particle beam to define the edge based on a position of the particle beam relative to a target of the particle beam, wherein, for all configurations of the fingers, the edge extends across less than an extent of the irradiation field.

38. The particle therapy system of claim 37, wherein the multiple elements comprise a first element and a second element, the first element for defining the edge, the edge being a first edge, and the second element for defining a second edge;

and

wherein the first edge and the second edge are controllable to move relative to the target.

39. The particle therapy system of claim 37, wherein the multiple elements are rotatable.

40. The particle therapy system of claim 37, wherein the scanning system is configured to scan the particle beam more quickly in interior sections of the target than at a perimeter of the target.

41. The particle therapy system of claim 37, wherein the scanning system is configured to scan the particle beam from different incident angles;

and

wherein the multiple elements are controllable to move based on movement of the particle beam as the particle beam is scanned from different incident angles.

42. The particle therapy system of claim 37, wherein the particle accelerator is a synchrocyclotron.