Anti-adherent composition

• US 9,969,885 B2
• Filed: 04/01/2015
• Issued: 05/15/2018
• Est. Priority Date: 07/31/2014
• Status: Active Grant

• Current Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Original Assignee: Kimberly-Clark Worldwide Incorporated (Kimberly-Clark Corporation)
• Inventors: Engelbrecht, Kathleen C., Vanden Heuvel, Amy L., Koenig, David W., Bhatt, Divesh, Chaudhary, Vinod, Wenzel, Scott W., Mundschau, Stacy A.
• Primary Examiner(s): Davis, Brian J
• Application Number:
  US15/329,611
• Publication Number:
  US 20170210900A1
• Time in Patent Office: 1,140 Days
• Field of Search: None
• CPC Class Codes: A61K 8/0208 Tissues; Wipes; Patches
• CPC Class Codes: A61K 8/731 Cellulose; Quaternized cellulose derivatives
• CPC Class Codes: A61K 8/8117 Homopolymers or copolymers of aromatic olefines, e.g. polystyrene; Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/8152 Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/817 Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
• CPC Class Codes: A61K 8/8182 Copolymers of vinyl-pyrrolidones. Compositions of derivatives of such polymers
• CPC Class Codes: A61K 8/84 obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
• CPC Class Codes: A61K 8/891 saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: C08G 77/045 containing less than 25 silicon atoms
• CPC Class Codes: C08G 77/16 to hydroxyl groups
• CPC Class Codes: C08G 77/46 containing polyether sequences
• CPC Class Codes: C08J 3/02 Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
• CPC Class Codes: C08L 101/00 Compositions of unspecified macromolecular compounds
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: C09D 183/04 Polysiloxanes

Abstract

Compositions for inhibiting the attachment of microbes to a biotic or abiotic surface are disclosed. The compositions include a carrier and an effective amount of an anti-adherent agent. The anti-adherent agents include Cyclopentasiloxane (and) Dimethiconol, sodium polystyrene sulfonate, Acrylates/Vinyl Neodecanoate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Polyquaternium-22, Hydroxypropyl methylcellulose, Polyquaternium-7, Acrylates/Aminoacrylates/C10-30 Alkyl PEG-20 Itaconate Copolymer and combinations thereof. Various delivery vehicles, such as wipes, may be used to deliver the composition to surfaces.

Claims

1. A composition for inhibiting the attachment of microbes to a biotic or an abiotic surface, the composition comprising:

a liquid carrier; and

an effective amount of an anti-adherent agent selected from the group consisting of Acrylates/Vinyl Neodecanoate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Hydroxypropyl Methylcellulose, Polyquaternium-22, Polyquaternium-7, Acrylates/Aminoacrylates/C10-30 Alkyl PEG-20 Itaconate Copolymer, and any combination thereof.

2. The composition of claim 1 wherein the liquid carrier is hydrophilic.

3. The composition of claim 1 further comprising a humectant selected from the group consisting of glycerin, glycerin derivatives, hyaluronic acid derivatives, betaine derivatives amino acids, amino acid derivatives, glycosaminoglycans, glycols, polyols, sugars, sugar alcohols, hydrogenated starch hydrolysates, hydroxy acids, hydroxy acid derivatives, salts of PCA, and any combination thereof.

4. The composition of claim 1 further comprising a humectant selected from the group consisting of honey, sorbitol, hyaluronic acid, sodium hyaluronate, betaine, lactic acid, citric acid, sodium citrate, glycolic acid, sodium glycolate ,sodium lactate, urea, propylene glycol, butylene glycol, pentylene glycol, ethoxydiglycol, methyl gluceth-10, methyl gluceth-20, PEG-2, PEG-3, PEG-4, PEG-5, PEG-6, PEG-7, PEG-8, PEG-9, PEG-10, xylitol, maltitol, and any combination thereof.

5. The composition of claim 1 further comprising an ingredient selected from the group consisting of an emollient, an emulsifier, an antimicrobial agent and any combination thereof.

6. The composition of claim 1 wherein the anti-adherent agent reduces the attachment of microbes to a polystyrene surface by at least 0.5 Log of bacteria according to the High Throughput Anti-adherent Test or the Viable Count Anti-Adherence Test Method.

7. The composition of claim 1 wherein the anti-adherent agent reduces the attachment of microbes to a polystyrene surface by at least 1 Log of bacteria according to a High Throughput Anti-adherent Test or the Viable Count Anti-Adherence Test Method.

8. The composition of claim 1 wherein the anti-adherent agent is present in the amount of 0.01% to 20% by weight of the composition.

9. The composition of claim 1 further comprising a foaming agent.

14. The composition of claim 1 wherein the composition is non-antimicrobial.

10. A wipe comprising:

a nonwoven substrate; and

an anti-adherent composition comprising 0.01% to 20% (by total weight of composition) of an anti-adherent agent; and

a liquid carrier;

wherein the composition reduces the adherence of E. coli on a surface by at least 0.5 Log according to a High Throughput Anti-adherence Test Method or the Viable Count Anti-Adherence Test Method, and wherein the anti-adherent agent is selected from the group of Acrylates/Vinyl Neodecanoate Crosspolymer, Ammonium Acryloyldimethyltaurate/VP Copolymer, Hydroxypropyl Methylcellulose, Polyquaternium-22, Polyquaternium-7, Acrylates/Aminoacrylates/C10-30 Alkyl PEG-20 Itaconate Copolymer, and any combination thereof.

11. The wipe of claim 10 wherein the anti-adherent composition further comprises a humectant.

12. The wipe of claim 10 wherein the anti-adherent agent is present in the amount of 0.1% to 10% (by total weight of the composition).

13. The wipe of claim 10 wherein the liquid carrier is an emulsion containing the anti-adherent agent.

15. The wipe of claim 10 wherein the composition is non-antimicrobial.

16. A composition for inhibiting the attachment of microbes to a biotic or an abiotic surface, the composition comprising:

a liquid carrier; and

an effective amount of an anti-adherent agent of sodium polystyrene polysulfate, wherein the sodium polystyrene polysulfate is present in an amount of less than 5% (by total weight of the composition).