Method of treating pain with an antibody against netrin-4, Unc5B or neogenin
First Claim
1. A method for the treatment of pain, comprising a step of administering, to a mammal, a therapeutically effective amount of an antibody against netrin-4, Unc5B or neogenin to treat pain in the mammal.
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Abstract
The present invention provides a screening method for pain suppressors, which method is characterized by using netrin-4 and/or a netrin-4 receptor to select a substance capable of inhibiting downstream signaling from netrin-4. According to the screening method of the present invention, pain suppressors useful as a preventive or therapeutic medicine for pain can be identified. The present invention also provides a pharmaceutical composition for prevention or treatment of pain, which composition comprises, as an active ingredient, a substance capable of inhibiting downstream signaling from netrin-4.
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1 Claim
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1. A method for the treatment of pain, comprising a step of administering, to a mammal, a therapeutically effective amount of an antibody against netrin-4, Unc5B or neogenin to treat pain in the mammal.
Specification