Low profile transcatheter heart valve

• US 9,974,652 B2
• Filed: 05/19/2017
• Issued: 05/22/2018
• Est. Priority Date: 06/06/2008
• Status: Active Grant

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: Hariton, Ilia, Benichou, Netanel, Nitzan, Yaacov, Felsen, Bella, Nguyen-Thien-Nhon, Diana, Khanna, Rajesh A., Nguyen, Son V., Levi, Tamir S., Pelled, Itai
• Primary Examiner(s): Gherbi, Suzette J
• Application Number:
  US15/599,802
• Publication Number:
  US 20170252157A1
• Time in Patent Office: 368 Days
• Field of Search: 623 124, 623 21- 219
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2/2433 using balloon catheter
• CPC Class Codes: A61F 2/2475 Venous valves
• CPC Class Codes: A61F 2/95 Instruments specially adapted for placement or removal of stents or stent-grafts
• CPC Class Codes: A61F 2/9522 Means for mounting a stent or stent-graft onto or into a placement instrument
• CPC Class Codes: A61F 2220/0033 made by longitudinally pushing a protrusion into a complementary-shaped recess, e.g. held by friction fit
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/0054 V-shaped
• CPC Class Codes: B05B 1/185 characterised by their outlet element; Mounting arrangements therefor
• CPC Class Codes: E03C 1/025 Water supply lines as such, e.g. shower hoses
• CPC Class Codes: E03C 1/066 allowing height adjustment of shower head
• CPC Class Codes: Y10T 29/49863 with prestressing of part

Abstract

A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve. The method can also include crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve, and removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.

Claims

1. A method of crimping an implantable prosthetic valve, comprising:

positioning at least a portion of the implantable prosthetic valve within an annular deformable sleeve;

inserting the implantable prosthetic valve and the deformable sleeve into a crimping apparatus;

operating the crimping apparatus to crimp the implantable prosthetic valve, which causes crimping jaws of the crimping apparatus to press the deformable sleeve against a frame of the implantable prosthetic valve, thereby causing portions of the deformable sleeve to protrude into openings in the frame; and

removing the implantable prosthetic valve from the crimping apparatus and from the deformable sleeve.

2. The method of claim 1, further comprising positioning a portion of a balloon catheter within the implantable prosthetic valve, and wherein the act of operating the crimping apparatus comprises crimping the prosthetic valve onto the balloon catheter.

3. The method of claim 1, wherein positioning the at least a portion of the implantable prosthetic valve within the deformable sleeve comprises positioning the entire implantable prosthetic valve within the deformable sleeve.

4. The method of claim 1, wherein:

the implantable prosthetic valve further comprises a plurality of leaflets; and

the deformable sleeve prevents the leaflets from protruding into open cells of the frame during the act of operating the crimping apparatus to crimp the implantable prosthetic valve.

5. A method of crimping an implantable prosthetic valve, comprising:

placing protective material over at least a portion of the implantable prosthetic valve, wherein the protective material is configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve;

crimping the implantable prosthetic valve with the protective material on the implantable prosthetic valve; and

removing the protective material from between the frame and the leaflet structure of the implantable prosthetic valve.

6. The method of claim 5, wherein the protective material is a deformed during the act of the crimping.

7. The method of claim 5, wherein the protective material is an annular sleeve configured to be placed around the implantable prosthetic valve, and wherein a portion of the sleeve protrudes into the open cells of the frame.

8. The method of claim 6, wherein the annular sleeve comprises fabric material.

9. The method of claim 5, wherein the act of crimping includes inserting the implantable prosthetic valve and the protective material into a crimping apparatus and advancing the implantable prosthetic valve and the protective material into an aperture defined by a plurality of crimping jaws of the crimping apparatus.

10. The method of claim 9, wherein the act of crimping further includes moving the crimping jaws radially inward against the frame of the implantable prosthetic valve and the protective material.

11. The method of claim 5, wherein at least a portion of the protective material extends radially inwardly beyond an inner diameter of the frame during the act of crimping.

12. A method of crimping an implantable prosthetic valve, comprising:

placing protective material at least partially over a leaflet structure of the implantable prosthetic valve;

inserting the implantable prosthetic valve and the protective material into a crimping apparatus;

crimping the implantable prosthetic valve with the crimping apparatus from a first, expanded state to a second, radially compressed state, wherein at least a portion of the protective material is disposed radially between the leaflet structure and an inner diameter of a frame of the implantable prosthetic valve to prevent damage to the leaflet structure; and

removing the protective material from the implantable prosthetic valve.

13. The method of claim 12, wherein the crimping apparatus comprises a plurality of crimping jaws, and crimping the implantable prosthetic valve includes moving the crimping jaws radially inwardly against the frame of the implantable prosthetic valve and the protective material.

14. The method of claim 12, wherein act of placing the protective material includes sliding the protective material relative to the frame and the leaflet structure of the implantable prosthetic valve.

15. The method of claim 12, wherein the protective material is disposed radially between the leaflet structure and the crimping apparatus during the act of crimping and prevents the crimping apparatus from directly contacting the leaflet structure.

16. The method of claim 12, wherein the protective material is an annular sleeve.

17. The method of claim 16, the act of removing the protective material includes peeling the sleeve away from the frame of the implantable prosthetic valve.

18. The method of claim 12, wherein the protective material is placed at least partially over the leaflet structure and the frame when the implantable prosthetic valve is in the expanded state.

19. The method of claim 12, wherein crimping the implantable prosthetic valve includes deforming the protective material.