Multipotent adult stem cells and methods for isolation
First Claim
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1. A cell culture comprising isolated expanded human non-embryonic, non-germ cells, the cells having undergone at least 10-40 cell doublings in culture, wherein the cells express oct4 and have a normal karyotype.
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Abstract
The invention provides isolated stem cells of non-embryonic origin that can be maintained in culture in the undifferentiated state or differentiated to form cells of multiple tissue types. Also provided are methods of isolation and culture, as well as therapeutic uses for the isolated cells.
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7 Claims
- 1. A cell culture comprising isolated expanded human non-embryonic, non-germ cells, the cells having undergone at least 10-40 cell doublings in culture, wherein the cells express oct4 and have a normal karyotype.
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