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Methods comprising desmopressin

  • US 9,974,826 B2
  • Filed: 05/21/2009
  • Issued: 05/22/2018
  • Est. Priority Date: 05/21/2008
  • Status: Active Grant
First Claim
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1. A method for reducing nocturnal urine volume in a male patient in need thereof comprising:

  • measuring the patient'"'"'s serum sodium level;

    administering to the patient, with a serum sodium level of at least 135 mmol/L, prior to bedtime an orodispersible dose of desmopressin of 50 μ

    g or 100 μ

    g, wherein the dose is measured as the free base of desmopressin;

    measuring the patient'"'"'s serum sodium level at a time interval after administration;

    continuing the administration of the dose of desmopressin over a treatment period if the male patient has a serum sodium level of at least 130 mmol/L;

    wherein the dose administered over the treatment period reduces the patient'"'"'s nocturnal urine volume.

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