System and method for independently operating multiple neurostimulation channels

• US 9,974,958 B2
• Filed: 09/15/2016
• Issued: 05/22/2018
• Est. Priority Date: 12/30/2009
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Griffith, Paul James
• Primary Examiner(s): Koharski, Christopher D
• Assistant Examiner(s): Dinga, Roland
• Application Number:
  US15/266,101
• Publication Number:
  US 20170001014A1
• Time in Patent Office: 614 Days
• Field of Search: 607 2, 607 45, 607 46, 607 48, 607 66, 607 72, 607 74, 607117
• CPC Class Codes: A61N 1/0531 Brain cortex electrodes
• CPC Class Codes: A61N 1/0534 Electrodes for deep brain stimulation
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/36125 Details of circuitry or electric components
• CPC Class Codes: A61N 1/36182 Direction of the electrical field, e.g. with sleeve around stimulating electrode
• CPC Class Codes: A61N 1/37223 Circuits for electromagnetic coupling
• CPC Class Codes: A61N 1/37241 providing test stimulations

Abstract

A multi-channel neurostimulation system comprises a plurality of electrical terminals configured for being respectively coupled to a plurality of electrodes, stimulation output circuitry including electrical source circuitry of the same polarity configured for generating a plurality of pulsed electrical waveforms in a plurality of timing channels, and control circuitry configured for instructing the stimulation output circuitry to serially couple the electrical source circuitry to different sets of the electrodes when pulses of the respective pulsed electrical waveforms do not temporally overlap each other, and for instructing the stimulation output circuitry to couple the electrical source circuitry to a union of the different electrode sets when pulses of the respective pulsed electrical waveforms temporally overlap each other.

Claims

1. A system, comprising:

a plurality of electrical terminals configured to be respectively coupled to a plurality of electrodes;

stimulation output circuitry configured to generate a plurality of pulsed electrical waveforms in a respective plurality of timing channels, wherein;

each of the plurality of timing channels corresponds to an electrode combination and a pulsed electrical waveform to be delivered using the electrode combination such that the plurality of timing channels includes a first timing channel and a second timing channel, the plurality of the pulsed electrical waveforms includes a first pulsed electrical waveform and a second pulsed electrical waveform, the plurality of electrodes includes first electrode combination and a second electrode combination, the first pulsed electrical waveform is delivered to the first electrode combination in the first timing channel and the second pulsed electrical waveform is delivered to the second electrode combination in the second timing channel, and

at least two of the plurality of pulsed electrical waveforms have a different pulse frequency relative to each other; and

control circuitry configured to;

sequentially couple the stimulation output circuitry to different sets of the electrodes when the respective pulsed electrical waveforms in the plurality of channels do not occur at the same time, including sequentially couple the stimulation output circuitry only to the first electrode combination when the first pulsed electrical waveform in the first timing channel provides a pulse and the second electrical waveform in the second timing channel does not provide a pulse, and then couple the stimulation output circuitry only to the second electrode combination when the second pulsed waveform in the second timing channel provides a pulse and the first electrical waveform in the first timing channel does not provide a pulse, and

couple the stimulation output circuitry to a union of the different electrode sets when the respective pulsed electrical waveforms in the plurality of channels occur at the same time, including when both the first pulsed electrical waveform in the first timing channel and the second electrical waveform in the second timing channel provide a pulse, wherein the union of the different electrode sets includes all of the electrodes in the first electrode combination and the second electrode combination.

2. The system of claim 1 wherein the stimulation output circuitry includes sink circuitry configured to sink an electrical current received from the plurality of electrodes.

3. The system of claim 1 wherein the stimulation output circuitry includes source circuitry configured to source an electrical current to the plurality of electrodes.

4. The system of claim 1 wherein the stimulation output circuitry includes a voltage source configured to generate the plurality of pulsed electrical waveforms.

5. The system of claim 1 wherein the pulsed electrical waveforms are defined by a respective plurality of stimulation parameter sets;

wherein the control circuitry is configured to obtain a digital representation of an electrode set from each of the stimulation parameter sets, combining the digital representations together to create a union of the digital representations, and output the digital representation union to the stimulation circuitry; and

wherein the stimulation output circuitry is configured to couple the stimulation output circuitry to the union of the different electrode sets in accordance with the digital representation union.

6. The neurostimulation system of claim 5, wherein each of the digital representations comprises a digital representation of current amplitude values for each electrode set, and wherein the control circuitry is configured to instruct the stimulation output circuitry to supply electrical current from the stimulation output circuitry to the different sets of the electrodes or the union of the different electrode sets in accordance with the current amplitude values.

7. The system of claim 1 wherein the stimulation output circuitry includes a current source configured to generate the plurality of pulsed electrical waveforms.

8. The system of claim 7, wherein the current source comprises a plurality of current branches, and wherein the control circuitry is configured to select a current magnitude for each electrode in the union of the different electrode sets by assigning one or more of the current branches to the respective electrode.

9. The system of claim 7 further comprising a current steering register for each timing channel, wherein each current register is configured to specify a set of output electrodes.

10. The system of claim 9 wherein each set of output electrodes is configured to provide treatment to a different region in a patient.

11. A method of delivering electrical stimulation energy from stimulation output circuitry to a plurality of electrodes, the method comprising:

generating a plurality of pulsed electrical waveforms in a respective plurality of timing channels, wherein;

each of the plurality of timing channels corresponds to an electrode combination and a pulsed electrical waveform to be delivered using the electrode combination such that the plurality of timing channels includes a first timing channel and a second timing channel, the plurality of the pulsed electrical waveforms includes a first pulsed electrical waveform and a second pulsed electrical waveform, the plurality of electrodes includes first electrode combination and a second electrode combination, the first pulsed electrical waveform is delivered to the first electrode combination in the first timing channel and the second pulsed electrical waveform is delivered to the second electrode combination in the second timing channel, and

at least two of the plurality of pulsed electrical waveforms have a different pulse frequency relative to each other; and

sequentially coupling the stimulation output circuitry to different sets of the electrodes when the respective pulsed electrical waveforms in the plurality of channels do not occur at the same time, including sequentially coupling the stimulation output circuitry only to the first electrode combination when the first pulsed electrical waveform in the first timing channel provides a pulse and the second electrical waveform in the second timing channel does not provide a pulse, and then couple the stimulation output circuitry only to the second electrode combination when the second pulsed waveform in the second timing channel provides a pulse and the first electrical waveform in the first timing channel does not provide a pulse; and

coupling the stimulation output circuitry to a union of the different electrode sets when the respective pulsed electrical waveforms in the plurality of channels occur at the same time, including when both the first pulsed electrical waveform in the first timing channel and the second electrical waveform in the second timing channel provide a pulse, wherein the union of the different electrode sets includes all of the electrodes in the first electrode combination and the second electrode combination.

12. The method of claim 11 further comprising sinking an electrical current received from the plurality of electrodes.

13. The method of claim 11 further comprising sourcing an electrical current to the plurality of electrodes.

14. The method of claim 11 further comprising generating the pulsed electrical waveforms with a voltage source.

15. The method of claim 11 further comprising:

defining the pulsed electrical waveforms by a respective plurality of stimulation parameter sets;

obtaining a digital representation of an electrode set from each of the stimulation parameter sets, wherein each of the digital representations comprises a current amplitude value;

combining the digital representations together to create a union of the digital representations;

delivering the union of digital representations the stimulation circuitry; and

coupling the stimulation output circuitry to the union of the different electrode sets in accordance with the digital representation union.

16. The method of claim 15, further comprising supplying electrical current to the different sets of the electrodes or the union of the different electrode sets in accordance with the current amplitude values.

17. The method of claim 11 further comprising generating the plurality of pulsed electrical waveforms with a current source.

18. The method of claim 17, further comprising selecting a current magnitude for each electrode in the union of the different electrode sets by assigning one or more current branches to the respective electrode.

19. The method of claim 17 further comprising specifying a set of output electrodes for each timing channel and storing an amplitude and polarity of a current for each set of output electrodes.

20. A non-transitory machine-readable medium including instructions, which when executed by a machine, cause the machine to deliver electrical stimulation energy from stimulation output circuitry to a plurality of electrodes, including:

generate a plurality of pulsed electrical waveforms in a respective plurality of timing channels, wherein;

each of the plurality of timing channels corresponds to an electrode combination and a pulsed electrical waveform to be delivered using the electrode combination such that the plurality of timing channels includes a first timing channel and a second timing channel, the plurality of the pulsed electrical waveforms includes a first pulsed electrical waveform and a second pulsed electrical waveform, the plurality of electrodes includes first electrode combination and a second electrode combination, the first pulsed electrical waveform is delivered to the first electrode combination in the first timing channel and the second pulsed electrical waveform is delivered to the second electrode combination in the second timing channel, and

at least two of the plurality of pulsed electrical waveforms have a different pulse frequency relative to each other; and

sequentially couple stimulation output circuitry to different sets of the electrodes when the respective pulsed electrical waveforms in the plurality of channels do not occur at the same time, including sequentially coupling the stimulation output circuitry only to the first electrode combination when the first pulsed electrical waveform in the first timing channel provides a pulse and the second electrical waveform in the second timing channel does not provide a pulse, and then couple the stimulation output circuitry only to the second electrode combination when the second pulsed waveform in the second timing channel provides a pulse and the first electrical waveform in the first timing channel does not provide a pulse; and

coupling the stimulation output circuitry to a union of the different electrode sets when the respective pulsed electrical waveforms in the plurality of channels occur at the same time, including when both the first pulsed electrical waveform in the first timing channel and the second electrical waveform in the second timing channel provide a pulse, wherein the union of the different electrode sets includes all of the electrodes in the first electrode combination and the second electrode combination.