Methods and systems for detecting the hydration of sensors
First Claim
1. A glucose sensor system, comprising:
- a subcutaneous or implantable glucose sensor, the sensor including a plurality of electrodes configured to be inserted into a body of a human subject; and
a sensor electronics device that is coupled to the sensor and includes;
a power source to apply a voltage signal to the sensor after said electrodes are inserted into the human subject'"'"'s body and prior to any measurement of a glucose level of the human subject;
an electrical characteristic measuring device that, prior to any measurement of said glucose level of the human subject, measures a resistance of the sensor and transmits a signal to indicate hydration of the sensor if the resistance is below a set criterion;
a detection circuit that receives the signal transmitted from the electrical characteristic measuring device and generates an interrupt after receipt thereof; and
a microcontroller that receives the interrupt from the detection circuit and transmits a signal representative of a voltage to the sensor to a digital-to-analog converter (DAC) which transmits a sequence of voltages to the sensor, wherein, after receipt of the interrupt from the detection circuit and after completion of the sequence of voltages, the sensor performs a first measurement of said glucose level of said human subject, such that no measurement of the glucose level is performed by the sensor prior to said receipt of said indication of hydration and completion of said sequence of voltages, wherein said sequence of voltages is transmitted to the sensor as a first voltage pulse having a magnitude of 0.535 volts, a second voltage pulse having a magnitude of 1.07 volts, a third voltage pulse having a magnitude of 0.535 volts, a fourth voltage pulse having a magnitude of 1.07 volts, a fifth voltage pulse having a magnitude of 0.535 volts, and a sixth voltage pulse having a magnitude of 1.07 volts, and wherein said first, third, and fifth voltage pulses are applied for 5 minutes, and said second, fourth, and sixth voltage pulses are applied for 2, 5, 10, 15, or 20 minutes.
1 Assignment
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Accused Products
Abstract
A sensor system includes a sensor and a sensor electronics device. The sensor includes a plurality of electrodes. The sensor electronics device includes a connection detection device, a power source, and a delay circuit. The connection detection device determines if the sensor electronics device is connected to the sensor and transmits a connection signal. The delay circuit receives the connection signal, waits a preset hydration time, and couples the regulated voltage from the power source to an electrode in the sensor after the preset hydration time has elapsed. Alternatively, the sensor electronics device may include an electrical detection circuit and a microcontroller. The electrical detection circuit determines if the plurality of electrodes are hydrated and generates an interrupt if the electrodes are hydrated. A microcontroller receives the interrupt and transmits a signal representative of a voltage to an electrode of the plurality of electrodes.
158 Citations
20 Claims
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1. A glucose sensor system, comprising:
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a subcutaneous or implantable glucose sensor, the sensor including a plurality of electrodes configured to be inserted into a body of a human subject; and a sensor electronics device that is coupled to the sensor and includes; a power source to apply a voltage signal to the sensor after said electrodes are inserted into the human subject'"'"'s body and prior to any measurement of a glucose level of the human subject; an electrical characteristic measuring device that, prior to any measurement of said glucose level of the human subject, measures a resistance of the sensor and transmits a signal to indicate hydration of the sensor if the resistance is below a set criterion; a detection circuit that receives the signal transmitted from the electrical characteristic measuring device and generates an interrupt after receipt thereof; and a microcontroller that receives the interrupt from the detection circuit and transmits a signal representative of a voltage to the sensor to a digital-to-analog converter (DAC) which transmits a sequence of voltages to the sensor, wherein, after receipt of the interrupt from the detection circuit and after completion of the sequence of voltages, the sensor performs a first measurement of said glucose level of said human subject, such that no measurement of the glucose level is performed by the sensor prior to said receipt of said indication of hydration and completion of said sequence of voltages, wherein said sequence of voltages is transmitted to the sensor as a first voltage pulse having a magnitude of 0.535 volts, a second voltage pulse having a magnitude of 1.07 volts, a third voltage pulse having a magnitude of 0.535 volts, a fourth voltage pulse having a magnitude of 1.07 volts, a fifth voltage pulse having a magnitude of 0.535 volts, and a sixth voltage pulse having a magnitude of 1.07 volts, and wherein said first, third, and fifth voltage pulses are applied for 5 minutes, and said second, fourth, and sixth voltage pulses are applied for 2, 5, 10, 15, or 20 minutes. - View Dependent Claims (2, 3, 4, 5)
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6. A glucose sensor system, comprising:
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a subcutaneous or implantable glucose sensor, the sensor including a plurality of electrodes configured to be inserted into a body of a human subject; and a sensor electronics device that is coupled to the sensor and includes; a power source to apply a voltage signal to the sensor after said electrodes are inserted into the human subject'"'"'s body and prior to any measurement of a glucose level of the human subject; an electrical characteristic measuring device that, prior to any measurement of said glucose level of the human subject, measures an impedance of the sensor and transmits a signal to indicate hydration of the sensor if the impedance is below a set criterion; a detection circuit that receives the signal transmitted from the electrical characteristic measuring device and generates an interrupt after receipt thereof; and a microcontroller that receives the interrupt from the detection circuit and transmits a signal representative of a voltage to the sensor to a digital-to-analog converter (DAC) which transmits a sequence of voltages to the sensor, wherein, after receipt of the interrupt from the detection circuit and after completion of the sequence of voltages, the sensor performs a first measurement of said glucose level of said human subject, such that no measurement of the glucose level is performed by the sensor prior to said receipt of said indication of hydration and completion of said sequence of voltages, wherein said sequence of voltages is transmitted to the sensor as a first voltage pulse having a magnitude of 0.535 volts, a second voltage pulse having a magnitude of 1.07 volts, a third voltage pulse having a magnitude of 0.535 volts, a fourth voltage pulse having a magnitude of 1.07 volts, a fifth voltage pulse having a magnitude of 0.535 volts, and a sixth voltage pulse having a magnitude of 1.07 volts and wherein said first, third, and fifth voltage pulses are applied for 5 minutes, and said second, fourth, and sixth voltage pulses are applied for 2, 5, 10, 15, or 20 minutes. - View Dependent Claims (7, 8, 9, 10)
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11. A glucose sensor system, comprising:
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a subcutaneous or implantable glucose sensor, the sensor including a plurality of electrodes configured to be inserted into a body of a human subject; and a sensor electronics device that is coupled to the sensor and includes; a power source to apply a voltage signal to the sensor after said electrodes are inserted into the human subject'"'"'s body and prior to any measurement of a glucose level of the human subject; an electrical characteristic measuring device that, prior to any measurement of said glucose level of the human subject, measures a resistance of the sensor and transmits a signal to indicate hydration of the sensor if the resistance is below a set criterion; a detection circuit that receives the signal transmitted from the electrical characteristic measuring device and generates an interrupt after receipt thereof; and a microcontroller that receives the interrupt from the detection circuit and transmits a signal representative of a voltage to the sensor to a digital-to-analog converter (DAC) which transmits a sequence of voltages to the sensor, wherein, after receipt of the interrupt from the detection circuit and after completion of the sequence of voltages, the that no measurement of the glucose level is performed by the sensor prior to said receipt of said indication of hydration and completion of said sequence of voltages, wherein said sequence of voltages is of said hydration and said sequence of voltages, wherein said sequence of voltages is transmitted to the sensor as a first voltage pulse having a magnitude of 0.535 volts, a second voltage pulse having a magnitude of 1.07 volts, a third voltage pulse having a magnitude of 0.535 volts, a fourth voltage pulse having a magnitude of 1.07 volts, a fifth voltage pulse having a magnitude of 0.535 volts, and a sixth voltage pulse having a magnitude of 1.07 volts, and wherein said first, third, and fifth voltage pulses are applied for 2 minutes, and said second, fourth, and sixth voltage pulses are applied for 5 minutes. - View Dependent Claims (12, 13, 14, 15)
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16. A glucose sensor system, comprising:
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a subcutaneous or implantable glucose sensor, the sensor including a plurality of electrodes configured to be inserted into a body of a human subject; and a sensor electronics device that is coupled to the sensor and includes; a power source to apply a voltage signal to the sensor after said electrodes are inserted into the human subject'"'"'s body and prior to any measurement of a glucose level of the human subject; an electrical characteristic measuring device that, prior to any measurement of said glucose level of the human subject, measures an impedance of the sensor and transmits a signal to indicate hydration of the sensor if the impedance is below a set criterion; a detection circuit that receives the signal transmitted from the electrical characteristic measuring device and generates an interrupt after receipt thereof; and a microcontroller that receives the interrupt from the detection circuit and transmits a signal representative of a voltage to the sensor to a digital-to-analog converter (DAC) which transmits a sequence of voltages to the sensor, wherein, after receipt of the interrupt from the detection circuit and after completion of the sequence of voltages, the sensor performs a first measurement of said glucose level of said human subject, such that no measurement of the glucose level is performed by the sensor prior to said receipt of said indication of hydration and completion of said sequence of voltages, wherein said sequence of voltages is transmitted to the sensor as a first voltage pulse having a magnitude of 0.535 volts, a second voltage pulse having a magnitude of 1.07 volts, a third voltage pulse having a magnitude of 0.535 volts, a fourth voltage pulse having a magnitude of 1.07 volts, a fifth voltage pulse having a magnitude of 0.535 volts, and a sixth voltage pulse having a magnitude of 1.07 volts and wherein said first, third, and fifth voltage pulses are applied for 2 minutes, and said second, fourth, and sixth voltage pulses are applied for 5 minutes. - View Dependent Claims (17, 18, 19, 20)
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Specification