Nutritional compositions containing structured fat globules and uses thereof

• US 9,980,506 B2
• Filed: 03/11/2013
• Issued: 05/29/2018
• Est. Priority Date: 03/11/2013
• Status: Active Grant

• Current Assignee: Mead Johnson Nutrition Company (Reckitt Benckiser Group PLC)
• Original Assignee: Mead Johnson Nutrition Company (Reckitt Benckiser Group PLC)
• Inventors: Banavara, Dattatreya, Alvey, John, Gonzalez, Juan
• Primary Examiner(s): GWARTNEY, ELIZABETH A
• Application Number:
  US13/794,270
• Publication Number:
  US 20140255538A1
• Time in Patent Office: 1,905 Days
• Field of Search: 426 2
• CPC Class Codes: A23C 9/14 in which the chemical composition of the milk is modified by non-chemical treatment
• CPC Class Codes: A23L 33/115 Fatty acids or derivatives thereof; Fats or oils
• CPC Class Codes: A23L 33/12 Fatty acids or derivatives thereof
• CPC Class Codes: A23L 33/135 Bacteria or derivatives thereof, e.g. probiotics
• CPC Class Codes: A23L 33/19 Dairy proteins
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2250/1578 Calcium
• CPC Class Codes: A23V 2250/1588 Copper
• CPC Class Codes: A23V 2250/1592 Iron
• CPC Class Codes: A23V 2250/1598 Iodine
• CPC Class Codes: A23V 2250/16 Potassium
• CPC Class Codes: A23V 2250/161 Magnesium
• CPC Class Codes: A23V 2250/1612 Manganese
• CPC Class Codes: A23V 2250/1614 Sodium
• CPC Class Codes: A23V 2250/1618 Phosphorus
• CPC Class Codes: A23V 2250/1642 Zinc
• CPC Class Codes: A23V 2250/1842 Lecithin
• CPC Class Codes: A23V 2250/1866 Conjugated Linoleic acid
• CPC Class Codes: A23V 2250/1868 Docosahexaenoic acid
• CPC Class Codes: A23V 2250/1876 : Long-chain fatty acids
• CPC Class Codes: A23V 2250/1882 : Polyunsaturated fatty acids
• CPC Class Codes: A23V 2250/194 : Triglycerides
• CPC Class Codes: A23V 2250/28 : Oligosaccharides
• CPC Class Codes: A23V 2250/304 : Choline
• CPC Class Codes: A23V 2250/54252 : Whey protein
• CPC Class Codes: A23V 2250/612 : Lactose
• CPC Class Codes: A23V 2250/702 : Vitamin A
• CPC Class Codes: A23V 2250/7042 : Vitamin B1
• CPC Class Codes: A23V 2250/7044 : Vitamin B2
• CPC Class Codes: A23V 2250/7046 : Vitamin B3 niacin
• CPC Class Codes: A23V 2250/7052 : Vitamin B6
• CPC Class Codes: A23V 2250/7056 : Vitamin B8 Folic acid
• CPC Class Codes: A23V 2250/706 : Vitamin B12
• CPC Class Codes: A23V 2250/708 : Vitamin C
• CPC Class Codes: A23V 2250/71 : Vitamin D
• CPC Class Codes: A23V 2250/712 : Vitamin E
• CPC Class Codes: A23V 2250/714 : Vitamin K
• CPC Class Codes: A23V 2250/72 : Biotin

Abstract

The present disclosure relates to a lipid source for nutritional compositions, comprising an enriched lipid fraction which comprises structured fat globules. The enriched lipid fraction provides fat globules having a desired size and fatty acid composition and may be stabilized by components such as phospholipids, cholesterol, milk-fat globule membrane protein and combinations thereof. Additionally, the disclosure relates to methods of supporting lipid digestion in a pediatric subject by providing a nutritional composition comprising an enriched lipid fraction having structured fat globules that are more accessible to lipases. The chemical composition, size and structure of the fat globules may improve digestion. The disclosed nutritional compositions may provide additive and or/synergistic beneficial health effects.

Claims

1. A nutritional composition comprising:

from about 6 g/100 kcal to about 22 g/100 kcal of a carbohydrate source,

from about 1 g/100 kcal to about 7 g/100 kcal of a protein source,

a lipid source comprising milk fat globules formed from an enriched lipid fraction derived from bovine milk, further wherein the milk fat globules comprise the following weight percentages of fatty adds based on the total weight of the fatty acids present in the milk fat globules;

50.7% saturated fatty acids, 35.4% mono-unsaturated fatty adds, 4.4% poly-unsaturated fatty adds, and 4.3% trans fatty acids, and

from about 0.2 mg/100 kcal to about 1.5 mg/100 kcal of a prebiotic, wherein the prebiotic is selected from the group consisting of polydextrose, galactooligosaccharide, and combinations thereof.

2. The nutritional composition of claim 1, wherein the average diameter of the milk fat globules range is at least about 2 μ

m.

3. The nutritional composition of claim 2, wherein the average diameter of the milk fat globules range is in the range of about 2 μ

m to about 13 μ

m.

4. The nutritional composition of claim 3, wherein the average diameter of the milk fat globules range is in the range of about 3 μ

m to about 6 μ

m.

5. The nutritional composition of claim 1, wherein the specific surface area of the milk fat globules range is in the range of about 0.9 m²/g to about 3 m²/g.

6. The nutritional composition of claim 1, wherein the milk fat globules comprise at least one phospholipid.

7. The nutritional composition of claim 1, further comprising docosahexaenoic acid.

8. The nutritional composition of claim 1, further comprising at least one probiotic.

9. The nutritional composition of claim 1, wherein the nutritional composition is an infant formula.

10. The nutritional composition of claim 7, wherein the docosahexaenoic acid is present in an amount of from about 5 mg/100 kcal to about 75 mg/100 kcal.