Method and system for electrode impedance measurement

• US 9,980,662 B2
• Filed: 05/18/2011
• Issued: 05/29/2018
• Est. Priority Date: 05/25/2010
• Status: Active Grant

• Current Assignee: NeuroWave Systems Inc.
• Original Assignee: NeuroWave Systems Inc.
• Inventors: Bibian, Stphane, Zikov, Tatjana
• Primary Examiner(s): EISEMAN, ADAM JARED
• Application Number:
  US13/110,455
• Publication Number:
  US 20110295096A1
• Time in Patent Office: 2,568 Days
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/291 for electroencephalography [EEG]
• CPC Class Codes: A61B 5/4094 Diagnosing or monitoring seizure diseases, e.g. epilepsy
• CPC Class Codes: A61B 5/4806 Sleep evaluation A61B5/4821 takes precedence; devices for inducing sleep A61M21/02
• CPC Class Codes: A61B 5/4821 Determining level or depth of anaesthesia A61B5/1106 takes precedence
• CPC Class Codes: A61B 5/7203 for noise prevention, reduction or removal
• CPC Class Codes: A61B 5/7221 Determining signal validity, reliability or quality A61B5/7207 and A61B5/7217 take precedence

Abstract

The present invention relates to measuring electrical impedance, and particularly to measuring impedance of electrodes used to acquire physiological signals. The measurement of electrode impedance is typically performed to ensure proper electrode-to-skin contact, and thus verify the quality of the acquired signals. Electrode-to-skin contact impedance has also clinical utility for monitoring, diagnosis, prognosis or treatment, as it can be used to measure skin conductivity, which is function of physiological processes. The present invention relates in particular to a substantially continuous method for performing such measurement. The measurement is performed in such a way that it does not affect the bioband, the range (or ranges) of frequencies that contains components used for diagnostic, prognostic, triage, and/or treatment purposes. The present invention therefore performs this impedance measurement without affecting the physiological signal while allowing for uninterrupted monitoring of said signal.

Claims

1. A device for the simultaneous measurement of electroencephalogram (EEG) signals and electrical impedance of applied (EEG) electrodes comprising:

at least three electrodes adapted to be attached to a subject, at least one electrode being for electrical grounding, at least one electrode providing a reference signal, and at least one EEG measurement electrode for acquisition of a physiological signal;

a processor for collection of the physiological signal and determining the electrical impedance of each electrode individually;

a variable current source capable of progressively increasing and decreasing electrical current for impedance measurement into the individual electrodes steadily over a period of time; and

a monitor to display the EEG physiological signal and calculated electrical impedance for each electrode utilized.

2. The device of claim 1 where the variable current source provides an electrical current at a frequency between 52 Hz and 58 Hz, exclusive.

3. The device of claim 1 wherein the variable current source is adapted to progressively increase and decrease the electrical current in order to eliminate perturbation of the physiological signal from supplying the electrical current.

4. The device of claim 1 where the variable current source provides a current waveform containing a number of frequencies that are outside the bioband of the physiological signal, where the bioband is comprised of all frequencies that carry any information used for diagnostic, prognostic, triage, or treatment purposes, and the maximum level of the impedance measurement current supplied is less than 5 μ

A.

5. The device of claim 1 where the variable current source amplitude can be progressively decreased to an amplitude of essentially zero amperage steadily over a period of time.

13. The device of claim 1 wherein the variable current source is adapted to progressively increase or decrease the impedance measurement current over period of time not less than 1 second.

6. A method for simultaneously measuring electroencephalogram (EEG) signals and electrical impedance of applied EEG electrodes comprising the steps of:

placing at least one grounding electrode on a subject;

placing at least two separate measurement EEG electrodes on a subject at distinct locations, to acquire at least one physiological signal corresponding to the voltage differential between the two measurement electrodes;

supplying and maintaining a first electrical current for impedance measurement to the first measurement electrode;

acquiring a first physiological signal from said subject using an acquisition device connected to the two measurement electrodes;

measuring a first amplitude of at least one frequency component corresponding to at least one of the current source frequency component from the first physiological signal;

calculating a first electrical impedance of the first measurement electrode based at least in part on the measured first amplitude of at least one frequency component corresponding to at least one of the current source frequency component from the first physiological signal;

supplying a progressively increasing second electrical current for impedance measurement to the second measurement electrode steadily over a period of time;

acquiring a second physiological signal from said subject;

measuring a second amplitude of at least one frequency component corresponding to at least one of the second current source frequency from the second physiological signal;

calculating an electrical impedance of the second measurement electrode based at least in part on the measured second amplitude from the second physiological signal;

reducing progressively the amplitude of the second electrical current for impedance measurement supplied to the second measurement electrode steadily over a period of time;

comparing the calculated first and second electrode impedances against predetermined thresholds; and

adjusting electrodes whose calculated electrical impedance exceeds the predetermined threshold by reapplying conductive fluid to the electrode(s), moving or repositioning the electrode(s), or replacing the electrode(s).

7. The method of claim 6 further comprising the step of calculating a second electrode impedance of the second measurement electrode by subtracting the first electrical impedance from combined electrical impedance.

8. The method of claim 6 where the electrical impedance measurement current is provided at a frequency between 52 Hz and 58 HZ, exclusive.

9. The method of claim 6 wherein the variable current source is adapted to progressively increase and decrease the electrical current in order to eliminate perturbation of the physiological signal from supplying the electrical current.

10. The method of claim 8 where the current source frequency is outside the bioband of the physiological signal, where the bioband is comprised of all frequencies that carry any information used for diagnostic, prognostic, triage, or treatment purposes, and the maximum level of the impedance measurement current supplied is less than 5 μ

A.

11. The method of claim 8 wherein the impedance measurement currents are progressively increased or decreased over period of time not less than 1 second.

12. The method of claim 8 where the second current amplitude can be progressively decreased to an essentially zero amperage progressively over a period of time.

14. A method for simultaneously Measuring electroencephalogram (EEG) signals and electrical impedance of applied EEG electrodes comprising the steps of:

placing at least one grounding electrode on a subject;

placing at least two separate measurement EEG electrodes on a subject at distinct locations, to acquire at least one physiological signal corresponding to the voltage differential between the two measurement electrodes;

supplying a progressively increasing first electrical current for impedance measurement to the first measurement electrode steadily over a period of time;

acquiring a first physiological signal from said subject using an acquisition device connected to the two measurement electrodes;

measuring a first amplitude of at least one frequency component corresponding to at least one of the current source frequency component from the first physiological signal;

calculating a first electrical impedance of the first measurement electrode based at least in part on the measured first amplitude of at least one frequency component corresponding to at least one of the current source frequency component from the first physiological signal;

reducing progressively the amplitude of the first electrical current for impedance measurement supplied to the first electrode steadily over a period of time;

supplying a progressively increasing second electrical current for impedance measurement to the second measurement electrode steadily over a period of time;

acquiring a second physiological signal from said subject;

measuring a second amplitude of at least one frequency component corresponding to at east one of the second current source frequency from the second physiological signal;

calculating a second electrical impedance corresponding to the second measurement electrode based at least in part on the measured second amplitude of at least one frequency component corresponding to at least one of the current source frequency component from the first physiological signal;

reducing progressively the amplitude of the second electrical current for impedance measurement supplied to the second measurement electrode steadily over a period of time;

comparing the calculated first and second electrode impedances against a predetermined threshold; and

adjusting electrodes whose calculated electrical impedance exceeds the predetermined threshold by reapplying conductive fluid to the electrode(s), moving or repositioning the electrode(s), or replacing the electrode(s).

15. The method of claim 14 wherein the first electrical current is progressively decreased simultaneously as the second electrical current is progressively increased.

16. The method of claim 14 wherein the variable current source is adapted to progressively increase and decrease the electrical current in order to eliminate perturbation of the physiological signal from supplying the electrical current.

17. The method of claim 14 where the current source frequency is outside the bioband of the physiological signal, where the bioband is comprised of all frequencies that carry any information used for diagnostic, prognostic, triage, or treatment purposes, and the maximum level of the impedance measurement current supplied is less than 5 μ

A.

18. The method of claim 14 wherein the impedance measurement currents are progressively increased or decreased over period of time not less than 1 second.

19. The method of claim 14 where the first and second current amplitudes can be progressively decreased to an essentially zero amperage.