Analyte monitoring device and methods

• US 9,980,669 B2
• Filed: 11/07/2012
• Issued: 05/29/2018
• Est. Priority Date: 11/07/2011
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Cole, Jean-Pierre, Fennell, Martin J.
• Primary Examiner(s): Mallari, Patricia
• Assistant Examiner(s): TOTH, KAREN E
• Application Number:
  US13/671,489
• Publication Number:
  US 20130116524A1
• Time in Patent Office: 2,029 Days
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/0026 characterised by the transmission medium
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/72 Signal processing specially adapted for physiological signals or for diagnostic purposes character recognition, recognising digital ink, document-oriented image-based pattern recognition G06V30/00; recognition or understanding of postal images G06V30/424
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F

Abstract

Methods and devices for providing application specific integrated circuit architecture for a two electrode analyte sensor or a three electrode analyte sensor are provided. Systems and kits employing the same are also provided.

Claims

1. An analyte monitoring device, comprising:

an analyte sensor having a plurality of sensor electrodes including a working electrode, a reference electrode and a counter electrode, the analyte sensor having at least a portion configured to be in contact with fluid under a skin surface, wherein the plurality of sensor electrodes generate at least one signal corresponding to a monitored analyte level in the fluid; and

sensor electronics coupled to the plurality of sensor electrodes of the analyte sensor, the sensor electronics including analog front end circuitry that includes an analog-to-digital converter configured to convert an analog voltage signal from the counter electrode to digital form,

wherein the analog front end circuitry comprises a first amplifier coupled to the reference electrode and to a first guard trace around the reference electrode,

wherein the analog front end circuitry comprises a second amplifier coupled to the counter electrode and to a second guard trace around the counter electrode, the first amplifier being different than the second amplifier,

wherein the analog front end circuitry is referenced to a reference potential; and

wherein the analyte monitoring device further comprises a charge pump coupled with a power supply, wherein the charge pump is adapted to boost power supply voltage, wherein the first amplifier is coupled to the charge pump to receive a boosted voltage from the charge pump, and wherein the analog-to-digital converter is configured to receive a voltage from the power supply that is different from the boosted voltage received by the first amplifier.

2. The device of claim 1, wherein the analog front end circuitry is provided with a fixed voltage between the working electrode and the reference electrode of the sensor to reference the analog front end circuitry of the sensor electronics to the reference potential.

3. The device of claim 2, wherein the fixed voltage includes a poise voltage associated with the analyte sensor.

4. The device of claim 1, wherein the analyte sensor and the sensor electronics are included within an integrated housing.

5. The device of claim 4, wherein the integrated housing is configured to be worn on a skin surface of a patient.

6. The device of claim 1, wherein the analyte sensor is configured to operate for a period of at least 14 days.

7. The device of claim 1, wherein the sensor electronics includes a data communication component to communicate information representative of the monitored analyte level to a remote device.

8. The device of claim 7, wherein the data communication component includes a radio frequency (RF) data communication component.

9. The device of claim 7, further comprising an antenna coupled to the data communication component.

10. The device of claim 9, wherein the antenna includes a loop antenna.

11. The device of claim 1, wherein the first amplifier and the second amplifier are each either a unity gain amplifier or a voltage follower.

12. A method, comprising:

positioning at least a portion of an analyte sensor in contact with fluid under a skin surface, the analyte sensor having a plurality of sensor electrodes including a working electrode, a reference electrode and a counter electrode, wherein the plurality of sensor electrodes of the analyte sensor generate at least one signal corresponding to a monitored analyte level in the fluid and are coupled to sensor electronics, wherein the sensor electronics include analog front end circuitry comprising an analog-to-digital converter; and

converting, by the analog-to-digital converter, an analog voltage signal from the counter electrode to digital form;

wherein the analog front end circuitry of the sensor electronics is referenced to a reference potential,

wherein a first guard trace is around the reference electrode and a second guard trace is around the counter electrode,

wherein a first amplifier is coupled to the reference electrode and the first guard trace,

wherein a second amplifier is coupled to the counter electrode and the second guard trace, the first amplifier being different than the second amplifier, and

wherein the first amplifier receives a boosted voltage from a charge pump adapted to boost power supply voltage, and wherein the analog-to-digital converter receives a voltage from the power supply that is different from the boosted voltage received by the first amplifier.

13. The method of claim 12, further including providing a fixed voltage between the working electrode and the reference electrode of the analyte sensor to reference the analog front end circuitry of the sensor electronics to the reference potential.

14. The method of claim 13, wherein the fixed voltage includes a poise voltage associated with the analyte sensor.

15. The method of claim 13, wherein the fixed voltage includes 40 mV.

16. The method of claim 12, wherein the analyte sensor is configured to operate for a period of at least 14 days.