Low profile non-symmetrical stent

• US 9,980,834 B2
• Filed: 11/25/2015
• Issued: 05/29/2018
• Est. Priority Date: 12/26/2007
• Status: Active Grant

• Current Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Original Assignee: Cook Medical Incorporated (Cook Group Incorporated)
• Inventors: Brocker, David, Dierking, William K., Leewood, Alan R., Roeder, Blayne A., Kratzberg, Jarin A., Rasmussen, Erik E.
• Primary Examiner(s): Woznicki, Jacqueline
• Application Number:
  US14/952,498
• Publication Number:
  US 20160074183A1
• Time in Patent Office: 916 Days
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/852 Two or more distinct overlapping stents
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/89 the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/061 provided with means for allowing access to secondary lumens
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/075 the stent being loosely attached to the graft material, e.g. by stitching
• CPC Class Codes: A61F 2002/826 more than one stent being applied sequentially
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2002/8486 provided on at least one of the ends
• CPC Class Codes: A61F 2002/91508 the meander having a difference in amplitude along the band
• CPC Class Codes: A61F 2002/91516 the meander having a change in frequency along the band
• CPC Class Codes: A61F 2002/91533 characterised by the phase between adjacent bands
• CPC Class Codes: A61F 2002/91541 Adjacent bands are arranged out of phase
• CPC Class Codes: A61F 2210/0014 using shape memory or superelastic materials, e.g. nitinol
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0054 : V-shaped
• CPC Class Codes: A61F 2230/0067 : conical
• CPC Class Codes: A61F 2250/0014 : having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
• CPC Class Codes: A61F 2250/006 : modular

Abstract

Various stents and stent-graft systems for treatment of medical conditions are disclosed. In one embodiment, an exemplary stent-graft system may be used for endovascular treatment of a thoracic aortic aneurysm. The stent-graft system may comprise proximal and distal components, each comprising a graft having proximal and distal ends, where upon deployment the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween. The proximal component may comprise a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where a radius of curvature of at least one of the proximal apices may be greater than the radius of curvature of at least one of the distal apices. The distal component may comprise a proximal z-stent coupled to the graft, where the proximal end of the graft comprises at least scallop formed therein that generally follows the shape of the proximal z-stent. Further, the distal component may comprise at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal component.

Claims

1. A stent-graft system for treatment of a medical condition, the stent-graft system comprising:

a proximal component comprising a graft having proximal and distal ends, and further comprising a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where at least one of the distal apices of the proximal stent is attached to the graft using one or more sutures,

where each proximal apex comprises a first curved portion and each distal apex comprises a second curved portion, where the first curved portion and the second curved portion each comprises at least one radius of curvature, and the radius of curvature of at least one of the proximal apices is greater than the radius of curvature of at least one of the distal apices; and

a distal component comprising a graft having proximal and distal ends, where, upon deployment, the proximal and distal components at least partially overlap with one another to permit continuous fluid flow therebetween,

where the distal component further comprises a proximal z-stent coupled to the graft, and where the proximal end of the graft comprises at least one scallop formed therein that generally follows the shape of the proximal z-stent,

where a first radius of curvature of one of the distal apices is from about 0.5 mm to about 1.5 mm,

where a second radius of curvature of one of the proximal apices is from about 4 mm to about 9 mm,

where a ratio of the first radius of curvature to the second radius of curvature is about 1;

2.6 to about 1;

18.

2. The stent-graft system of claim 1 where the distal component further comprises at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal end of the distal component.

3. The stent-graft system of claim 2 wherein the at least one z-stent stent coupled to the distal end of the graft comprises at least one barb oriented in a proximal direction.

4. The stent-graft system of claim 1 where each of the proximal apices of the proximal stent are circumferentially offset from the distal apices.

5. The stent-graft system of claim 1 where the first radius of curvature is about 1 mm, and the second radius of curvature is about 6 mm.

6. The stent-graft system of claim 1 where the proximal component comprises at least five additional z-stents coupled to the graft at locations distal to the proximal stent.

7. The stent-graft system of claim 6 where, of the at least five additional z-stents, proximal and distal z-stents are coupled to an inner surface of the graft and at least three intermediate z-stents are coupled to an outer surface of the graft.

8. A stent-graft system for treatment of a medical condition, the stent-graft system comprising:

a proximal component comprising a graft having proximal and distal ends, and further comprising a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where at least one of the distal apices of the proximal stent is attached to the graft using one or more sutures,

where each proximal apex comprises a first curved portion and each distal apex comprises a second curved portion, where the first curved portion and the second curved portion each comprises at least one radius of curvature, and the radius of curvature of at least one of the proximal apices is greater than the radius of curvature of at least one of the distal apices; and

a distal component comprising a graft having proximal and distal ends, where, upon deployment, the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween,

where the distal component further comprises a proximal z-stent coupled to the graft, and where the proximal end of the graft comprises at least one scallop formed therein that generally follows the shape of the proximal z-stent, and

where the distal component further comprises at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal end of the distal component,

where a first radius of curvature of one of the distal apices is from about 0.5 mm to about 1.5 mm,

where a second radius of curvature of one of the proximal apices is from about 4 mm to about 9 mm,

where a ratio of the first radius of curvature to the second radius of curvature is about 1;

2.6 to about 1;

18.

9. The stent-graft system of claim 8 where each of the proximal apices of the proximal stent are circumferentially offset from the distal apices.

10. The stent-graft system of claim 8 where the proximal component comprises at least five additional z-stents coupled to the graft at locations distal to the proximal stent.

11. The stent-graft system of claim 8 where the first radius of curvature is about 1 mm, and the second radius of curvature is about 6 mm.

12. A stent-graft system for treatment of a medical condition, the stent-graft system comprising:

a proximal component comprising a graft having proximal and distal ends, and further comprising a proximal stent having a plurality of proximal and distal apices connected by a plurality of generally straight portions, where at least one of the distal apices of the proximal stent is attached to the graft using one or more sutures,

where each proximal apex comprises a first curved portion and each distal apex comprises a second curved portion, where the first curved portion and the second curved portion each comprises at least one radius of curvature, and the radius of curvature of at least one of the proximal apices is greater than the radius of curvature of at least one of the distal apices; and

a distal component comprising a graft having proximal and distal ends, where, upon deployment, the proximal and distal components at least partially overlap with one another to provide a fluid passageway therebetween,

where the distal component further comprises at least one z-stent stent coupled to the distal end of the graft and extending distally therefrom that reduces proximal migration of the distal end of the distal component,

where a first radius of curvature of one of the distal apices is from about 0.5 mm to about 1.5 mm,

where a second radius of curvature of one of the proximal apices is from about 4 mm to about 9 mm ,

where a ratio of the first radius of curvature to the second radius of curvature is about 1;

2.6 to about 1;

18.

13. The stent-graft system of claim 12 where the distal component further comprises a proximal z-stent coupled to the graft, and where the proximal end of the graft comprises at least one scallop formed therein that generally follows the shape of the proximal z-stent.

14. The stent-graft system of claim 12 where the at least one z-stent stent coupled to the distal end of the graft comprises at least one barb oriented in a proximal direction.

15. The stent-graft system of claim 12 where each of the proximal apices of the proximal stent are circumferentially offset from the distal apices.

16. The stent-graft system of claim 12 where the first radius of curvature is about 1 mm, and the second radius of curvature is about 6 mm.

17. The stent-graft system of claim 12 where the proximal component comprises at least five additional z-stents coupled to the graft at locations distal to the proximal stent.