Ion beam extraction apparatus and method of use thereof

• US 9,981,147 B2
• Filed: 08/04/2016
• Issued: 05/29/2018
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: ProTom International Holding Corporation
• Original Assignee: James Patrick Bennett, Lee W. Davis, Mark R. Amato
• Inventors: Lee, W. Davis, Amato, Mark R., Bennett, James P.
• Primary Examiner(s): Maskell, Michael
• Application Number:
  US15/228,626
• Publication Number:
  US 20160339272A1
• Time in Patent Office: 663 Days
• Field of Search: 250396 R, 2504921, 2504923
• CPC Class Codes: A61B 6/032 Transmission computed tomography [CT]
• CPC Class Codes: A61B 6/4216 using storage phosphor screens
• CPC Class Codes: A61B 6/4258 for detecting non x-ray radiation, e.g. gamma radiation A61B6/037 takes precedence
• CPC Class Codes: A61B 6/5205 involving processing of raw data to produce diagnostic data
• CPC Class Codes: A61N 2005/1054 using a portal imaging system
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1095 Elements inserted into the radiation path within the system, e.g. filters or wedges
• CPC Class Codes: A61N 2005/1097 Means for immobilizing the patient
• CPC Class Codes: A61N 5/1039 using functional images, e.g. PET or MRI
• CPC Class Codes: A61N 5/1067 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/107 in real time, i.e. during treatment
• CPC Class Codes: A61N 5/1077 Beam delivery systems
• CPC Class Codes: A61N 5/1081 Rotating beam systems with a specific mechanical construction, e.g. gantries
• CPC Class Codes: A61N 5/1082 having multiple beam rotation axes
• CPC Class Codes: G21K 1/08 Deviation, concentration or focusing of the beam by electric or magnetic means electron-optical arrangements in electric discharge tubes H01J29/46; details, e.g. electric or magnetic deviating means for direct voltage accelerators or in accelerators using single pulses H05H5/02; arrangements for injecting particles into orbits H05H7/08; arrangements for ejecting particles from orbits H05H7/10
• CPC Class Codes: G21K 5/04 with beam-forming means

Abstract

The invention comprises an apparatus and method of use thereof for extracting ions from an ion source, such as for use in cancer treatment or tomographic imaging. The extraction apparatus uses a triode extraction system, with the ion source and/or first electrode held at a first potential; an extraction electrode held at a second potential; and a gating electrode, positioned between the ion source and the extraction electrode, oscillating and/or alternating between a first suppression potential proximate that of the ion source potential and a second extraction potential between the ion source potential and the extraction electrode potential. Optionally, the ion source comprises an electron cyclotron resonance ion source.

Claims

1. A method for extracting ions, comprising the steps of:

providing ions with an ion source, said ion source comprising;

an electron resonance cyclotron ion source, said electron resonance cyclotron generating the ions, the ions comprising at least one of;

cations; and

anions;

providing a triode extraction system, comprising;

said ion source maintained at a first potential;

an extraction electrode maintained at a third potential differing from said first potential; and

a gating electrode positioned between said ion source and said extraction electrode;

alternatingly (1) suppressing extraction of the ions from said ion source and (2) extracting a set of ions from said ion source through changing a second potential of said gating electrode from proximate the first potential to a value between the first potential and the third potential, said step of alternatingly (1) suppressing extraction of the ions from said ion source and (2) extracting a set of ions from said ion source further comprising the step of;

intermittently oscillating the second potential from +30±

10 kV to 0±

5 kV.

2. The method of claim 1, further comprising the steps of:

maintaining the first potential at a first absolute value greater than 20 kV;

maintaining the third potential at 0±

10 kV; and

maintaining the second potential at a second absolute value at least 0.1 kV larger than the first potential, said step of maintaining the second potential functioning to suppress extraction of the ions from said ion source.

3. The method of claim 1, said cations comprising at least one of:

protons;

C⁴⁺; and

C⁶⁺.

4. The method of claim 3, further comprising the sequential steps of:

focusing the cations with a radio-frequency quadrupole;

accelerating the cations with a synchrotron; and

treating a tumor of a patient with the cations.

5. The method of claim 3, further comprising the step of:

imaging a tumor of a patient with the cations, said step of imaging comprising a step of forming a three-dimensional tomographic image of the tumor.

7. The method of claim 1, said ion source comprising at least one of:

an electron resonance cyclotron ion source;

a dual plasmatron ion source;

an indirectly heated cathode ion source;

a Freeman type ion source; and

a Bernas type ion source.

6. A method for extracting ions, comprising the steps of:

providing ions with an ion source, said ion source comprising;

an electron resonance cyclotron ion source, said electron resonance cyclotron generating the ions, the ions comprising at least one of;

cations; and

anions;

providing a triode extraction system, comprising;

said ion source maintained at a first potential;

an extraction electrode maintained at a third potential differing from said first potential; and

a gating electrode positioned between said ion source and said extraction electrode;

alternatingly (1) suppressing extraction of the ions from said ion source and (2) extracting a set of ions from said ion source through changing a second potential of said gating electrode from proximate the first potential to a value between the first potential and the third potential;

imaging a tumor with a first two-dimensional imaging system using the ions extracted from said ion source; and

imaging the tumor with a second two-dimensional imaging system using X-rays, said steps of imaging the tumor with said first two-dimensional imaging system and imaging the tumor with said second two-dimensional imaging system overlapping in time,

said cations comprising at least one of;

protons;

C⁴⁺; and

C⁶⁺.

8. An apparatus for extracting ions, comprising:

an ion source configured to provide the ions,

a triode extraction system, comprising;

said ion source maintained at a first potential during use;

an extraction electrode maintained at a third potential, during use, differing from said first potential; and

a gating electrode positioned between said ion source and said extraction electrode;

an electrical ground connection to said extraction electrode;

a first power supply configured to maintain the first potential of said ion source at 30±

20 kV; and

second power supply configured to cycle the second potential between the first potential and the third potential,

wherein a second potential of said gating electrode during use is alternatingly (1) suppressing extraction of the ions from said ion source and (2) extracting a set of ions from said ion source through changing the second potential of said gating electrode from proximate the first potential to a value between the first potential and the third potential.

9. The apparatus of claim 8, said ion source comprising at least one of:

an electron resonance cyclotron ion source;

a dual plasmatron ion source;

an indirectly heated cathode ion source;

a Freeman type ion source; and

a Bernas type ion source.

10. The apparatus of claim 9, further comprising an ion beam path, comprising:

a path from said electron resonance cyclotron ion source, through a synchrotron and into a position above a patient positioning support.

11. The apparatus of claim 10, the ion beam path further comprising,

a section from the position above said patient positioning support into a scintillation plate of a tomographic imaging system.

12. A system of extracting ions, comprising the step of:

providing ions with an ion source;

providing a triode extraction system, comprising;

said ion source maintained at a first potential;

an extraction electrode maintained at a third potential differing from said first potential; and

a gating electrode positioned between said ion source and said extraction electrode; and

at alternating times;

suppressing extraction of the ions from said ion source using a first state of an electric field between said ion source and said gating electrode at a second potential of +30±

10 kV; and

extracting a set of ions from said ion source through using a second state of the electric field by changing the second potential of said gating electrode from proximate the first potential to a value of;

(1) 0±

5 kV and (2) between the first potential and the third potential.