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Size self-limiting compositions and test devices for measuring analytes in biological fluids

  • US 9,982,289 B2
  • Filed: 05/11/2011
  • Issued: 05/29/2018
  • Est. Priority Date: 12/13/2004
  • Status: Active Grant
First Claim
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1. A reactive formulation for measuring the amount of an analyte in a biological fluid comprising:

  • (a) a water-soluble swellable polymer matrix including water-insoluble particles having a nominal size of about 0.05 to 20 μ

    m; and

    (b) an enzyme system for reacting with said analyte,wherein the weight ratio of said water-insoluble particles to said water-soluble swellable polymer matrix is about 1/2 to 2.1/1, wherein the reactive formulation has a thickness of about 6 to 16 μ

    m.

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