Analyte sensors and methods of using same
First Claim
Patent Images
1. A biosensor, comprising:
- a first substrate;
a second substrate disposed over the first substrate;
an electrode disposed between the first substrate and second substrate;
a spacer disposed between the first and second substrates and defining a sample chamber; and
a dry composition disposed on an area of the electrode, the composition comprising an analyte detection reagent and electrically conductive particles in an amount of about 102 to about 1010 conductive particles/mm2,wherein the analyte detection reagent comprises an analyte-responsive enzyme and a redox mediator and the electrically conductive particles provide for uniform distribution of the analyte-responsive enzyme and the redox mediator on the area of the electrode.
1 Assignment
0 Petitions
Accused Products
Abstract
Provided are sensors for determining the concentration of an analyte in a sample fluid. In certain embodiments, the sensors include conductive particles and exhibit improved uniformity of distribution of one or more sensing chemistry components, increased effective working electrode surface area, and/or reduced entry of interfering components into a sample chamber of the sensor. Methods of using and manufacturing the sensors are also provided.
40 Citations
26 Claims
-
1. A biosensor, comprising:
-
a first substrate; a second substrate disposed over the first substrate; an electrode disposed between the first substrate and second substrate; a spacer disposed between the first and second substrates and defining a sample chamber; and a dry composition disposed on an area of the electrode, the composition comprising an analyte detection reagent and electrically conductive particles in an amount of about 102 to about 1010 conductive particles/mm2, wherein the analyte detection reagent comprises an analyte-responsive enzyme and a redox mediator and the electrically conductive particles provide for uniform distribution of the analyte-responsive enzyme and the redox mediator on the area of the electrode. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
-
Specification